Zobrazeno 1 - 10
of 32
pro vyhledávání: '"George T Kannarkat"'
Critical role of regulator G-protein signaling 10 (RGS10) in modulating macrophage M1/M2 activation.
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81785 (2013)
Regulator of G protein signaling 10 (RGS10), a GTPase accelerating protein (GAP) for G alpha subunits, is a negative regulator of NF-κB in microglia. Here, we investigated the role of RGS10 in macrophages, a closely related myeloid-derived cell type
Externí odkaz:
https://doaj.org/article/ea99784166514d88945257448f8114bf
Autor:
Madelyn C. Houser, Oihane Uriarte Huarte, Rebecca L. Wallings, Cody E. Keating, Kathryn P. MacPherson, Mary K. Herrick, George T. Kannarkat, Sean D. Kelly, Jianjun Chang, Nicholas H. Varvel, Jessica E. Rexach, Malú Gámez Tansey
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionProgranulin (PGRN) is a secreted glycoprotein, the expression of which is linked to several neurodegenerative diseases. Although its specific function is still unclear, several studies have linked it with lysosomal functions and immune sy
Externí odkaz:
https://doaj.org/article/4d8a321115ff4a7a8acb3699a6026cab
Autor:
Madelyn C. Houser, W. Michael Caudle, Jianjun Chang, George T. Kannarkat, Yuan Yang, Sean D. Kelly, Danielle Oliver, Valerie Joers, Kathleen M. Shannon, Ali Keshavarzian, Malú Gámez Tansey
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-23 (2021)
Abstract Background The etiology of sporadic Parkinson’s disease (PD) remains uncertain, but genetic, epidemiological, and physiological overlap between PD and inflammatory bowel disease suggests that gut inflammation could promote dysfunction of d
Externí odkaz:
https://doaj.org/article/8e618e46d41448b989d12a0fc10bd262
Autor:
Lori N. Eidson, George T. Kannarkat, Christopher J. Barnum, Jianjun Chang, Jaegwon Chung, Chelsea Caspell-Garcia, Peggy Taylor, Brit Mollenhauer, Michael G. Schlossmacher, Larry Ereshefsky, Mark Yen, Catherine Kopil, Mark Frasier, Kenneth Marek, Vicki S. Hertzberg, Malú G. Tansey
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-16 (2017)
Abstract Background Efforts to identify fluid biomarkers of Parkinson’s disease (PD) have intensified in the last decade. As the role of inflammation in PD pathophysiology becomes increasingly recognized, investigators aim to define inflammatory si
Externí odkaz:
https://doaj.org/article/4759130fbf4b43dfb829cdfe656a57b3
Autor:
Kathryn P. MacPherson, Pradoldej Sompol, George T. Kannarkat, Jianjun Chang, Lindsey Sniffen, Mary E. Wildner, Christopher M. Norris, Malú G. Tansey
Publikováno v:
Neurobiology of Disease, Vol 102, Iss , Pp 81-95 (2017)
Clinical and animal model studies have implicated inflammation and peripheral immune cell responses in the pathophysiology of Alzheimer's disease (AD). Peripheral immune cells including T cells circulate in the cerebrospinal fluid (CSF) of healthy ad
Externí odkaz:
https://doaj.org/article/1010916aeda24b02a7611cb0b33b23a5
Publikováno v:
Mov Disord Clin Pract
BACKGROUND: Exercise and physical therapy (PT) can improve motor function and quality of life in individuals with Parkinson's disease (PD), but their role in hospitalization avoidance is not well‐studied. OBJECTIVES: To determine the longitudinal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03212bc27352987acaf771c886bb8ac6
https://doi.org/10.1002/mdc3.13456
https://doi.org/10.1002/mdc3.13456
Autor:
George T. Kannarkat
Publikováno v:
Neurological Sciences. 43:5125-5127
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e72c9ff56a8ee6017fe677b44f43283
https://doi.org/10.1007/s10072-022-06098-5
https://doi.org/10.1007/s10072-022-06098-5
Publikováno v:
Tremor and Other Hyperkinetic Movements. 12
The last decade has seen development of numerous novel antipsychotic drugs with unique mechanisms including long-acting formulations for clinical use. A comparative assessment of these new drugs with each other and previous antipsychotics have not be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e711c0b85d260812782e1b2ffeae66
https://doi.org/10.5334/tohm.695
https://doi.org/10.5334/tohm.695
Publikováno v:
Journal of the neurological sciences. 432
This study assessed the utility of correction formulas for procedural peripheral blood admixture with cerebrospinal fluid (CSF) in adult patients using in vitro addition of peripheral blood.Participants from the Johns Hopkins CSF Disorders Center wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24e06a7d61dd13bc5632053d40fca0f
https://pubmed.ncbi.nlm.nih.gov/34929498
https://pubmed.ncbi.nlm.nih.gov/34929498
Autor:
Danielle Oliver, Madelyn C. Houser, Kathleen M. Shannon, Valerie Joers, Jianjun Chang, Malú G. Tansey, Ali Keshavarzian, W. Michael Caudle, Sean D. Kelly, George T. Kannarkat, Yuan Yang
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-23 (2021)
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-23 (2021)
Background The etiology of sporadic Parkinson’s disease (PD) remains uncertain, but genetic, epidemiological, and physiological overlap between PD and inflammatory bowel disease suggests that gut inflammation could promote dysfunction of dopamine-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0368eb67a1b442601ec822aba89ab3a3
https://doi.org/10.1186/s40478-021-01240-4
https://doi.org/10.1186/s40478-021-01240-4