Zobrazeno 1 - 10
of 54
pro vyhledávání: '"George T Eisenhoffer"'
Autor:
Lorena Maili, Bhavna Tandon, Qiuping Yuan, Simone Menezes, Frankie Chiu, S. Shahrukh Hashmi, Ariadne Letra, George T. Eisenhoffer, Jacqueline T. Hecht
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Craniofacial development is a complex and tightly regulated process and disruptions can lead to structural birth defects, the most common being nonsyndromic cleft lip and palate (NSCLP). Previously, we identified FOS as a candidate regulator of NSCLP
Externí odkaz:
https://doaj.org/article/b8947a3aa9854a0798e4c7d5d1bfb66c
Autor:
Lorena Maili, Oscar E. Ruiz, Philip H. Kahan, Frankie Chiu, Stephen T. Larson, S. Shahrukh Hashmi, Jacqueline T. Hecht, George T. Eisenhoffer
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/a3ff8240280d45c0b8a8a920f3710f7b
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101073- (2022)
Summary: Epithelial tissues sustain barrier function by removing and replacing aberrant or unfit cells. Here, we describe approaches to evaluate epithelial restorative capacity after inducing cell loss in zebrafish larvae. We provide details to quant
Externí odkaz:
https://doaj.org/article/1213ff88a5084842b1bf32807eb5f8b4
Autor:
Sebastian Wurster, Oscar E. Ruiz, Alexander M. Tatara, Dimitrios P. Kontoyiannis, George T. Eisenhoffer
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100963- (2021)
Summary: Epithelia provide the first line of defense against foreign pathogens, and disruption of tissue homeostasis frequently allows for opportunistic infections. Here we provide a protocol for induction of epithelial cell loss in zebrafish larvae,
Externí odkaz:
https://doaj.org/article/8c3176e5094d431eac1fff5bd8545e84
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100600- (2021)
Summary: Cell elimination by extrusion is important for epithelial homeostasis, but knowing when and where cells will extrude has made in vivo studies difficult. Here, we describe a step-by-step protocol for inducing cell extrusion from the larval ze
Externí odkaz:
https://doaj.org/article/7725aa9553634b1d9ec3b860db4381e2
Autor:
Courtney K. Brock, Stephen T. Wallin, Oscar E. Ruiz, Krystin M. Samms, Amrita Mandal, Elizabeth A. Sumner, George T. Eisenhoffer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Damaged epithelial tissues are known to compensate for cell death through compensatory cell divisions to maintain epithelial integrity. Here, the authors show in living epithelia that dying cells stimulate adjacent stem cells to divide through caspas
Externí odkaz:
https://doaj.org/article/36038ed7967345729d64f073b9d12a1c
Autor:
Sebastian Wurster, Oscar E. Ruiz, Krystin M. Samms, Alexander M. Tatara, Nathaniel D. Albert, Philip H. Kahan, Anh Trinh Nguyen, Antonios G. Mikos, Dimitrios P. Kontoyiannis, George T. Eisenhoffer
Publikováno v:
Cell Reports, Vol 34, Iss 12, Pp 108896- (2021)
Summary: Severe and often fatal opportunistic fungal infections arise frequently following mucosal damage caused by trauma or cytotoxic chemotherapy. Interaction of fungal pathogens with epithelial cells that comprise mucosae is a key early event ass
Externí odkaz:
https://doaj.org/article/090b8750f4e64706818b17aa866b5303
Autor:
Abiud Cantu Gutierrez, Manuel Cantu Gutierrez, Alexander M Rhyner, Oscar E Ruiz, George T Eisenhoffer, Joshua D Wythe
Publikováno v:
PLoS Biology, Vol 17, Iss 6, p e3000343 (2019)
The zebrafish Danio rerio is a powerful model system to study the genetics of development and disease. However, maintenance of zebrafish husbandry records is both time intensive and laborious, and a standardized way to manage and track the large amou
Externí odkaz:
https://doaj.org/article/81f17d17588c431fac22098eb2455dc4
Autor:
Lorena Maili, Oscar E. Ruiz, Philip Kahan, Frankie Chiu, Stephen T. Larson, S. Shahrukh Hashmi, Jacqueline T. Hecht, George T. Eisenhoffer
Publikováno v:
Disease Models & Mechanisms.
Facial development requires a complex and coordinated series of cellular events, that when perturbed, can lead to structural birth defects. A quantitative approach to quickly assess morphological changes could address how genetic or environmental inp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97c8ba98fe17308461afbbdd09365e50
https://doi.org/10.1242/dmm.049868
https://doi.org/10.1242/dmm.049868
Autor:
Yao Yu, Rolando Alvarado, Lauren E Petty, Ryan J Bohlender, Douglas M Shaw, Jennifer E Below, Nada Bejar, Oscar E Ruiz, Bhavna Tandon, George T Eisenhoffer, Daniel L Kiss, Chad D Huff, Ariadne Letra, Jacqueline T Hecht
Publikováno v:
Hum Mol Genet
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is a common, severe craniofacial malformation that imposes significant medical, psychosocial and financial burdens. NSCL/P is a multifactorial disorder with genetic and environmental facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ea418e0c8dd33434bb4e30a4442976
https://doi.org/10.1093/hmg/ddac037
https://doi.org/10.1093/hmg/ddac037