Zobrazeno 1 - 10
of 46
pro vyhledávání: '"George S. Charames"'
Autor:
Mariusz Shrestha, Sasha Blay, Sydney Liang, David Swanson, Jordan Lerner-Ellis, Brendan Dickson, Andrew Wong, George S. Charames
Publikováno v:
The Journal of Molecular Diagnostics. 25:320-330
Supplementary Figure Legends 1-2 and Table 1 from Activation of Tumor-Specific Splice Variant Rac1b by Dishevelled Promotes Canonical Wnt Signaling and Decreased Adhesion of Colorectal Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06818f051f68541b4d57484166fb1d66
https://doi.org/10.1158/0008-5472.22366275
https://doi.org/10.1158/0008-5472.22366275
Rac1b is a tumor-specific splice variant of the Rac1 GTPase that displays limited functional similarities to Rac1. We have shown previously a novel cross-talk between Rac1 and β-catenin, which induces canonical Wnt pathway activation in colorectal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e129ecc71413da29ce831566e0cf72
https://doi.org/10.1158/0008-5472.c.6495072.v1
https://doi.org/10.1158/0008-5472.c.6495072.v1
Supplementary Table 1 from Activation of Tumor-Specific Splice Variant Rac1b by Dishevelled Promotes Canonical Wnt Signaling and Decreased Adhesion of Colorectal Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee51eadb840af1f00e802855c80e94b
https://doi.org/10.1158/0008-5472.22366272
https://doi.org/10.1158/0008-5472.22366272
Supplementary Figure 1 from Activation of Tumor-Specific Splice Variant Rac1b by Dishevelled Promotes Canonical Wnt Signaling and Decreased Adhesion of Colorectal Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b658abd9c40f42726298f1b2c6830c
https://doi.org/10.1158/0008-5472.22366281
https://doi.org/10.1158/0008-5472.22366281
Supplementary Figure 2 from Activation of Tumor-Specific Splice Variant Rac1b by Dishevelled Promotes Canonical Wnt Signaling and Decreased Adhesion of Colorectal Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dbd4760d2649867d238df954d53c85a
https://doi.org/10.1158/0008-5472.22366278.v1
https://doi.org/10.1158/0008-5472.22366278.v1
Autor:
Nimish Mittal, Lianne McLean, Dmitry Rozenberg, Laura McGillis, Robert Bleakney, Juan C. Guzman, Aliza Weinrib, Sandra Tavares, Laura Hussey, Camille Laflamme, Colleen H. Parker, Hanna Faghfoury, Stephanie Buryk-Iggers, Stephanie Varriano, Yvonne Tse, P. Maxwell Slepian, Daniel Santa Mina, Hance Clarke, Louis W. C. Liu, Christopher J. Nielson, Christian Veillette, Arnon Adler, Maxim Rachinsky, Laura Lopez-Hernandez, George S. Charames, Joel T. Katz
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-9 (2021)
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases
Ehlers-Danlos Syndrome (EDS) are a heterogeneous group of genetic connective tissue disorders, and typically manifests as weak joints that subluxate/dislocate, stretchy and/or fragile skin, organ/systems dysfunction, and significant widespread pain.
Autor:
Michelle M. Axford, Ron Agatep, Marcos Clavier, Stacey Hume, Elizabeth Spriggs, Andrea K Vaags, George S. Charames, Harriet Feilotter, Nicholas A. Watkins, Amanda C. Smith, Tracy Tucker, Matthew S. Lebo, Vanessa Di Gioacchino, Jordan Lerner-Ellis, Ian Bosdet, Mohammad R. Akbari, William D. Foulkes, Chloe Mighton, Sean S. Young, Lorena Lazo de la Vega, Talia Silver, Ryan E. Lamont, Laura Semenuk, Robert Tomaszewski, Christian R. Marshall, Nancy Hamel, Justin Mayers, Henry K. Wong, Jillian S. Parboosingh, Marsha Speevak, Aly Karsan, George Chong, Sherryl Taylor
Publikováno v:
J Med Genet
BackgroundThis study aimed to identify and resolve discordant variant interpretations across clinical molecular genetic laboratories through the Canadian Open Genetics Repository (COGR), an online collaborative effort for variant sharing and interpre
Autor:
Jordan Lerner-Ellis, Nicholas A. Watkins, Andrew Wong, Chloe Mighton, Martin C. Chang, Conxi Lazaro, George S. Charames, Vanessa Di Gioacchino
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 147:871-879
The aim of this study was to determine the diagnostic yield of multigene panel testing among patients referred with hereditary breast and ovarian cancer (HBOC). Patients who met provincial eligibility criteria were tested at the Advanced Molecular Di
Autor:
Olga Gajic‐Veljanoski, Chunmei Li, Alexis K. Schaink, Jennifer Guo, Nadine Shehata, George S. Charames, Barbra Vrijer, Gwen Clarke, Petros Pechlivanoglou, Nanette Okun, Rita Kandel, Joseph Dooley, Caroline Higgins, Vivian Ng, Nancy Sikich
Publikováno v:
TransfusionREFERENCES. 62(5)
We sought to determine the cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies in Canada.We developed two probabilistic state-transition (Markov) microsimulation models to compare fetal