WASP integrates substrate topology and cell polarity to guide neutrophil migration

Autor: Rachel M. Brunetti, Gabriele Kockelkoren, Preethi Raghavan, George R.R. Bell, Derek Britain, Natasha Puri, Sean R. Collins, Manuel D. Leonetti, Dimitrios Stamou, Orion D. Weiner

Publikováno v: Brunetti, R M, Kockelkoren, G, Raghavan, P, Bell, G R R, Britain, D, Puri, N, Collins, S R, Leonetti, M D, Stamou, D & Weiner, O D 2022, ' WASP integrates substrate topology and cell polarity to guide neutrophil migration ', Journal of Cell Biology, vol. 221, no. 2, e202104046 . https://doi.org/10.1083/jcb.202104046
The Journal of cell biology, vol 221, iss 2

To control their movement, cells need to coordinate actin assembly with the geometric features of their substrate. Here, we uncover a role for the actin regulator WASP in the 3D migration of neutrophils. We show that WASP responds to substrate topolo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737b4acf3174f8324ab190368a42c1fc
https://curis.ku.dk/ws/files/309279317/jcb_202104046.pdf