Zobrazeno 1 - 10
of 23
pro vyhledávání: '"George R. King"'
Autor:
Stephen Winchester, Alex Castellarnau, Kashif Jabbar, Meera Nadir, Kapila Ranasinghe, Xavier Masramon, George R. Kinghorn, Isaac John, Jeremy R. A. Paull
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1173 (2024)
Background/Objectives: Dendrimer-based astodrimer sodium nasal spray was assessed for its ability to reduce SARS-CoV-2 load in outpatients with COVID-19, which remains a severe illness for vulnerable groups. Methods: This was a randomised, double-bli
Externí odkaz:
https://doaj.org/article/8328b88d31f24c06a1dcb7cc099e0bf0
Publikováno v:
Neuropsychologia. 85:278-286
Anthrozoological neuroscience, which we propose as the use of neuroscience techniques to study human-animal interaction, may help to elucidate mechanisms underlying the associated psychological, physiological, and other purported health effects. This
Autor:
Thomas Ernst, Helenna Nakama, Andrew V. Stenger, Rachael M. K. Gonzales, Linda Chang, Weiran Deng, George R. King
Publikováno v:
The Journal of Neuroscience. 31:17923-17931
Cannabis is the most abused illegal substance in the United States. Alterations in brain function and motor behavior have been reported in chronic cannabis users, but the results have been variable. The current study aimed to determine whether chroni
Autor:
Alex Castellarnau, Graham P. Heery, Aynaz Seta, Carolyn A. Luscombe, George R. Kinghorn, Peter Button, Philip McCloud, Jeremy R. A. Paull
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Astodrimer sodium is a dendrimer molecule with antiviral and virucidal activity against SARS-CoV-2 and other respiratory viruses in vitro, and has previously been shown to be safe and well tolerated, and not systemically absorbed, when appli
Externí odkaz:
https://doaj.org/article/025250ececcc40b783bcdea2a8a0134f
Publikováno v:
Psychopharmacology. 212:243-249
Methamphetamine (METH) is a widely abused psychostimulant that is associated with neurotoxicity and neurocognitive impairments in adults. However, the effects of METH use on neurocognitive performance of adolescents are unclear.Fifty-four adolescent
Publikováno v:
Journal of Neuroimmune Pharmacology. 5:582-591
Methamphetamine (METH) is a widely abused drug. However, little is known about the effects of chronic METH consumption on HPA axis function and psychiatric symptomatology in adolescent METH users. The current study evaluated psychiatric symptoms and
Publikováno v:
Behavioral Neuroscience. 118:150-156
The roles that psychostimulant sensitization and tolerance play in temporal perception in the seconds-to-minutes range were assessed in rats. Cocaine (20 mg/kg/day) was administered for 2 weeks either intermittently via daily injections (induces sens
Publikováno v:
European Journal of Pharmacology. 449:253-259
A functional down-regulation of central serotonin3 (5-HT3) receptors represents a partial mechanism of the tolerance to cocaine induced by the continuous administration of cocaine. Blocking this down-regulation by co-administering continuous cocaine
Publikováno v:
Experimental and Clinical Psychopharmacology. 1:80-91
Publikováno v:
Pharmacology Biochemistry and Behavior. 43:45-51
Rats were exposed to daily schedule-induced polydipsia sessions in which solutions of cocaine HCl were available. Both cocaine solution concentration (0.08–0.32 mg/ml) and session duration (0.25–3 h) were varied to determine their effects on loco