Zobrazeno 1 - 10
of 105
pro vyhledávání: '"George R. Hoffmann"'
Publikováno v:
Dose-Response, Vol 7 (2009)
Quantitative features of dose responses were analyzed for 2,189 candidate anticancer agents in 13 strains of yeast ( Saccharomyces cerevisiae ). The agents represent a diverse class of chemical compounds including mustards, other alkylating agents, a
Externí odkaz:
https://doaj.org/article/519891db761344228d148a00ba300cec
Autor:
George R. Hoffmann
Publikováno v:
Dose-Response, Vol 7 (2009)
The hormesis concept has broad implications for biology and the biomedical sciences. This perspective on hormesis concentrates on toxicology and toxicological risk assessment and secondarily explores observations from other fields. It considers the v
Externí odkaz:
https://doaj.org/article/af72d66dadb34da38a4c3e7923fd7cbd
Autor:
Jan Beyea, George R. Hoffmann
Publikováno v:
Radiation Research. 199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8a24280c35db0a97dceb26d7a8e4233
https://doi.org/10.1667/rade-21-00217.1
https://doi.org/10.1667/rade-21-00217.1
Autor:
George R. Hoffmann
Publikováno v:
Mutation Research/Reviews in Mutation Research. 780:106-120
Reflections is a component of Mutation Research Reviews devoted to historical and philosophical themes pertaining to the subject of mutation. Reflections was initiated in 1999 and has included a broad array of topics centered on mutation research, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c74b2116a95a1670f80984022fcc9ae
https://doi.org/10.1016/j.mrrev.2019.05.004
https://doi.org/10.1016/j.mrrev.2019.05.004
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 819:38-46
Hormesis is defined as a biphasic dose-response where biological effects of low doses of a stressor demonstrate the opposite effect to high-dose effects of the same stressor. Hormetic, or J-shaped, dose-response relationships are relatively rarely ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82bae8485ca15adb11f33e0f5854fdab
https://doi.org/10.1016/j.mrgentox.2017.05.002
https://doi.org/10.1016/j.mrgentox.2017.05.002
Autor:
George R. Hoffmann
Publikováno v:
Mutation Research/Reviews in Mutation Research. :108383
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e1299a4aa98fe88985cc5af64c6aa02
https://doi.org/10.1016/j.mrrev.2021.108383
https://doi.org/10.1016/j.mrrev.2021.108383
Publikováno v:
Environmental and Molecular Mutagenesis. 57:575-578
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c5e5cc4c476ca5e100124897165d866
https://doi.org/10.1002/em.22056
https://doi.org/10.1002/em.22056
Publikováno v:
Mutation Research/Reviews in Mutation Research. 769:63-66
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e47709ad7cb05ff76c74346f4f7b640
https://doi.org/10.1016/j.mrrev.2016.07.005
https://doi.org/10.1016/j.mrrev.2016.07.005
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. :23-30
The lacZ reversion assay in Escherichia coli measures point mutations that occur by specific base substitutions and frameshift mutations. The tester strains cannot use lactose as a carbon source (Lac(-)), and revertants are easily detected by growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60359acc96f47fc706ca9e7d5f302ed0
https://doi.org/10.1016/j.mrgentox.2015.04.008
https://doi.org/10.1016/j.mrgentox.2015.04.008
Autor:
Jason P. Tartaglione, Amanda M. Laterza, Lindsey K. MacNeil, Andrew V. Moczula, George R. Hoffmann
Publikováno v:
Environmental and Molecular Mutagenesis. 54:384-396
The assay for trp5 gene conversion and ilv1-92 reversion in Saccharomyces cerevisiae strain D7 was used to characterize the induction of an adaptive response by hydrogen peroxide (H2O2). Effects of a small priming dose on the genotoxic effects of a l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ca502dd836969ac83112324b4f8e2b4
https://doi.org/10.1002/em.21785
https://doi.org/10.1002/em.21785