Zobrazeno 1 - 10
of 39
pro vyhledávání: '"George R. Flentke"'
Autor:
Yanping Huang, George R. Flentke, Olivia C. Rivera, Nipun Saini, Sandra M. Mooney, Susan M. Smith
Publikováno v:
Cells, Vol 13, Iss 5, p 440 (2024)
Prenatal alcohol exposure (PAE) is a leading cause of neurodevelopmental disability through its induction of neuronal growth dysfunction through incompletely understood mechanisms. Ribosome biogenesis regulates cell cycle progression through p53 and
Externí odkaz:
https://doaj.org/article/417bc7ba4fdc44fea223c6e62aa833be
Autor:
Kelly E. Brannan, Kaylee K. Helfrich, George R. Flentke, Susan M. Smith, Kimberly A. Livingston, Christine Jansen van Rensburg
Publikováno v:
Poultry Science, Vol 101, Iss 5, Pp 101748- (2022)
ABSTRACT: Genetic selection for rapid growth in broilers has inadvertently resulted in increased susceptibility to heat stress, particularly in male birds. Increased oxidative stress associated with hyperthermia may be reduced by avian uncoupling pro
Externí odkaz:
https://doaj.org/article/acda6c96b86b4bce8c832c02ca015407
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
Prenatal alcohol exposure (PAE) causes distinctive facial characteristics in some pregnancies and not others; genetic factors may contribute to this differential vulnerability. Ethanol disrupts multiple events of neural crest development including in
Externí odkaz:
https://doaj.org/article/1324e8d7f0794296a61bcd2d73ed1689
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169351 (2017)
Fetal alcohol spectrum disorder (FASD) is a leading cause of neurodevelopmental disability. Individuals with FASD may exhibit a characteristic facial appearance that has diagnostic utility. The mechanism by which alcohol disrupts craniofacial develop
Externí odkaz:
https://doaj.org/article/2f5e642aa8a840eba6a479c54d0a3b7a
Autor:
George R. Flentke, Pamela J. Kling, Camille A. Kezer, Shane M. Huebner, Sze Ting Cecilia Kwan, Nipun Saini, Kaylee K. Helfrich, Susan M. Smith
Publikováno v:
Alcohol
Prenatal alcohol exposure (PAE) causes developmental abnormalities known as fetal alcohol spectrum disorder (FASD). Maternal iron status modulates the severity of these defects in the offspring. Because the placenta is central in supporting fetal dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::493720edb7369ff5b36074f1dc738b53
https://doi.org/10.1016/j.alcohol.2019.11.003
https://doi.org/10.1016/j.alcohol.2019.11.003
Autor:
Kelly E. Brannan, Kaylee K. Helfrich, George R. Flentke, Susan M. Smith, Kimberly A. Livingston, Christine Jansen van Rensburg
Publikováno v:
Poultry science. 101(5)
Genetic selection for rapid growth in broilers has inadvertently resulted in increased susceptibility to heat stress, particularly in male birds. Increased oxidative stress associated with hyperthermia may be reduced by avian uncoupling protein (avUC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6cb8376b9c739aee8ded59e9dc36a03
https://pubmed.ncbi.nlm.nih.gov/35278756
https://pubmed.ncbi.nlm.nih.gov/35278756
Autor:
Echoleah S Rufer, Tuan D Tran, Megan M Attridge, Matthew E Andrzejewski, George R Flentke, Susan M Smith
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47499 (2012)
Fetal alcohol spectrum disorders (FASD) are the leading non-genetic cause of neurodevelopmental disability in children. Although alcohol is clearly teratogenic, environmental factors such as gravidity and socioeconomic status significantly modify ind
Externí odkaz:
https://doaj.org/article/7a0365a6c02c41ed9080a250268a68f3
Autor:
Kaylee K. Helfrich, Sharon E. Blohowiak, Susan M. Smith, Nipun Saini, George R. Flentke, Pamela J. Kling, Sze Ting Cecilia Kwan, Juna Abazi, Shane M. Huebner
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND Prenatal alcohol exposure (PAE) causes long-term growth and neurodevelopmental deficits that are worsened by maternal iron deficiency (ID). In our preclinical rat model, PAE causes fetal anemia, brain ID, and elevated hepatic iron via incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df42b31c6142a6d9361405f02207685f
https://pubmed.ncbi.nlm.nih.gov/31524964
https://pubmed.ncbi.nlm.nih.gov/31524964
BACKGROUND: Prenatal alcohol exposure (PAE) causes distinctive craniofacial anomalies that arise, in part, from the apoptotic elimination of neural crest (NC) progenitors that form the face. This vulnerability of NC to alcohol is puzzling as they nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9ad775e2ba74542ed9b77ed36305dce
https://europepmc.org/articles/PMC7017393/
https://europepmc.org/articles/PMC7017393/
Publikováno v:
Birth Defects Research Part C: Embryo Today: Reviews. 102:210-220
Fetal alcohol spectrum disorder (FASD) is a leading cause of neurodevelopmental disability. Some affected individuals possess distinctive craniofacial deficits, but many more lack overt facial changes. An understanding of the mechanisms underlying th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::441735e7c4667a3ca888f031705453a6
https://doi.org/10.1002/bdrc.21078
https://doi.org/10.1002/bdrc.21078