Zobrazeno 1 - 7
of 7
pro vyhledávání: '"George R. Abraham"'
Publikováno v:
American Heart Journal Plus, Vol 41, Iss , Pp 100388- (2024)
Externí odkaz:
https://doaj.org/article/23a6076e2b594446b78f600c835f9880
Autor:
George R. Abraham, Andrew J. Morrow, Joana Oliveira, Jonathan R. Weir-McCall, Emma E. Davenport, Colin Berry, Anthony P. Davenport, Stephen P. Hoole
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 39, Iss , Pp 100980- (2022)
Introduction: Microvascular angina is a common cause of ischemia with non-obstructive coronary arteries (INOCA) and limited therapeutic options are available to those affected. Endothelin-1 (ET-1) is a potent vasoconstrictor implicated in the pathoph
Externí odkaz:
https://doaj.org/article/a2b66f21b03b40d1a68bbecbda27f947
Autor:
George R. Abraham, Duuamene Nyimanu, Rhoda E. Kuc, Janet J. Maguire, Anthony P. Davenport, Stephen P. Hoole
Publikováno v:
Journal of Interventional Cardiology, Vol 2022 (2022)
Objective. Coronary microvascular dysfunction (CMD) can complicate successful percutaneous coronary intervention (PCI). The potent endogenous vasoconstrictor peptide Endothelin-1 (ET-1) may be an important mediator. To investigate the mechanism, we s
Externí odkaz:
https://doaj.org/article/c6aa952e63c74751af16c0fd94c49375
Autor:
Thomas L. Williams, Robert R. Ruffolo, Eliot H. Ohlstein, Janet J. Maguire, Théophile Godfraind, Anthony P. Davenport, Pedro D'Orléans-Juste, George R. Abraham
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Endothelin receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Endothelin Receptors [24]) are activated by the endogenous 21 amino-acid peptides endothelins 1-3 (endothelin-1, endothelin-2 and endothelin-3).
Autor:
Jonathan JH Bray, Mazhar Warraich, Michael G Whitfield, Christina Udani Peter, Ranu Baral, Mahmood Ahmad, Shazaib Ahmad, George R Abraham, Ali Kirresh, Muhammad Salman Sahibzada, Adnan Muzaffar, Joseph Tomson, Pier D Lambiase, Gabriella Captur, Amitava Banerjee, Rui Providencia
Publikováno v:
Cochrane Database of Systematic Reviews. 2023
Publikováno v:
Cell.
The potent vasoconstrictor peptide endothelin-1 has long been recognized as a physiological regulator of vascular tone. However, pharmacological blockade of the endothelin-1 pathway has few proven indications thus far. A recent clinical trial for res
Autor:
George R. Abraham, Rhoda E. Kuc, Magnus Althage, Peter J. Greasley, Philip Ambery, Janet J. Maguire, Ian B. Wilkinson, Stephen P. Hoole, Joseph Cheriyan, Anthony P. Davenport
Publikováno v:
Journal of molecular and cellular cardiology. 167
Virus induced endothelial dysregulation is a well-recognised feature of severe Covid-19 infection. Endothelin-1 (ET-1) is the most highly expressed peptide in endothelial cells and a potent vasoconstrictor, thus representing a potential therapeutic t