Zobrazeno 1 - 10
of 308
pro vyhledávání: '"George R, Clark"'
Autor:
David P. Kelly, Melanie Spotheim-Maurizot, Denise Sy, Chris Clark, Jonathan M. White, Pavel N. Lobachevsky, George R. Clark, Christopher J. Squire, Monica E. Reum, Sam Broadhurst, Roger F. Martin
12 pages of supplementary material (Materials and Methods, 3 tables, 3 figures, references)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c41de755fa09d10e49491e3658d37c3
https://doi.org/10.1158/0008-5472.22363523
https://doi.org/10.1158/0008-5472.22363523
Autor:
David P. Kelly, Melanie Spotheim-Maurizot, Denise Sy, Chris Clark, Jonathan M. White, Pavel N. Lobachevsky, George R. Clark, Christopher J. Squire, Monica E. Reum, Sam Broadhurst, Roger F. Martin
New analogues of the minor groove binding ligand Hoechst 33342 have been investigated in an attempt to improve radioprotective activity. The synthesis, DNA binding, and in vitro radioprotective properties of methylproamine, the most potent derivative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a751037758badc16f0de0f758d41369f
https://doi.org/10.1158/0008-5472.c.6493754.v1
https://doi.org/10.1158/0008-5472.c.6493754.v1
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 7, Pp m804-m805 (2009)
The crystal structure of a racemic mixture of the title ruthenium(II) complex, [RuCl(C30H30O2P2)2]CF3SO3·2CH2Cl2, reveals that the coordination geometry about the coordinatively unsaturated metal centre is approximately trigonal-pyramidal, with the
Externí odkaz:
https://doaj.org/article/e066acb84df1463e928d6a01f6a51696
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 1, Pp m52-m52 (2009)
The crystal structure of the title compound, [Ru(C12H12O6)(C18H15P)2(CO)], confirms its formulation as a ruthenabenzofuran, with a slightly distorted octahedral coordination environment at the RuII ion, and mutually trans triphenylphosphine ligands.
Externí odkaz:
https://doaj.org/article/7891d2847d17467781d2ab3cfb0b4ab3
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 10, Pp o2031-o2031 (2008)
The title compound, C15H24N2O4Si, was prepared by the reaction of (3-acetamido-5-nitrobenzyl)methanol with tert-butyldimethylsilyl chloride and is a key intermediate in the synthesis of novel nonsymmetrical DNA minor groove-binding agents. There are
Externí odkaz:
https://doaj.org/article/12f68659cee5475ea7549dbba55a2734
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 8, Pp o1470-o1470 (2008)
The title compound, C8H8N2O7S, an intermediate in the synthesis of N,N-bis(2-hydroxyethyl)-3,5-dinitroaniline, exists as a discrete molecule; the nitro groups are twisted with respect to the aromatic system [dihedral angles = 17.0 (1) and 26.3 (1)°]
Externí odkaz:
https://doaj.org/article/fec3199bfc904f76ab60d9354e47c94b
Publikováno v:
Journal of Paleontology. 90:389-399
Transmitted light and scanning electron imaging of sectioned specimens ofConulariaandParaconularia, prepared using HCl etching and critical point drying, revealed that their periderm is composed of extremely thin (approximately 0.5–3 µm), variably
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d484c9791ebdb6242f0845626c94880b
https://doi.org/10.1017/jpa.2016.63
https://doi.org/10.1017/jpa.2016.63
Publikováno v:
Dalton Trans.. 43:17006-17016
Double aza-Michael addition of n-butylamine to the two acrylamide groups of acyclic N(2),N(6)-bis(6-acrylamidopyridin-2-yl)pyridine-2,6-dicarboxamide gives the corresponding macrocycle, H₄L. H₄L has potential coordination pockets associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07bc165c52b96814a28bc535bd7661c8
https://doi.org/10.1039/c4dt00765d
https://doi.org/10.1039/c4dt00765d
Autor:
John Yu-Chih Chang, Guo-Liang Lu, Ralph J. Stevenson, Penelope J. Brothers, George R. Clark, K. Jane Botting, Dianne M. Ferry, Moana Tercel, William R. Wilson, William A. Denny, David C. Ware
Publikováno v:
Inorganic Chemistry. 52:7688-7698
A series of cobalt(III) complexes of the potent DNA minor groove alkylator (1-(chloromethyl)-5-hydroxy-1H-pyrrolo[3,2-f]quinolin-3(2H)-yl)(5,6,7-trimethoxy-1H-indol-2-yl)methanone (3; seco-CPyI-TMI), with cyclam or cyclen auxiliary ligands (L3 and L5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ff0788c384c313dd45881ffa6ff255
https://doi.org/10.1021/ic4006967
https://doi.org/10.1021/ic4006967