Zobrazeno 1 - 10
of 14
pro vyhledávání: '"George Poy"'
Autor:
Kari M. Wojtanik, Keith Edgemon, Srikant Viswanadha, Brigette Lindsey, Martin Haluzik, Weiping Chen, George Poy, Marc Reitman, Constantine Londos
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 6, Pp 1068-1079 (2009)
We investigated the role of LMNA in adipose tissue by developing a novel mouse model of lipodystrophy. Transgenic mice were generated that express the LMNA mutation that causes familial partial lipodystrophy of the Dunnigan type (FPLD2). The phenotyp
Externí odkaz:
https://doaj.org/article/009057fc8a974808abbaecc922eda7f8
Autor:
Weiping Chen, Herbert Tabor, George Poy, Margaret C. Cam, David Stiles, Manas K. Chattopadhyay
Publikováno v:
Yeast. 26:531-544
The naturally occurring polyamines putrescine, spermidine or spermine are ubiquitous in all cells. Although polyamines have prominent regulatory roles in cell division and growth, precise molecular and cellular functions are not well-established in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b65d640fca9c31e48b6486a10d8949
https://doi.org/10.1002/yea.1703
https://doi.org/10.1002/yea.1703
Autor:
Keith Edgemon, Martin Haluzik, George Poy, Marc L. Reitman, Weiping Chen, Constantine Londos, Kari M. Wojtanik, Srikant Viswanadha, Brigette Lindsey
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 6, Pp 1068-1079 (2009)
We investigated the role of LMNA in adipose tissue by developing a novel mouse model of lipodystrophy. Transgenic mice were generated that express the LMNA mutation that causes familial partial lipodystrophy of the Dunnigan type (FPLD2). The phenotyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0408136e41f42ca3e72c883a9f5cb0
https://doi.org/10.1194/jlr.m800491-jlr200
https://doi.org/10.1194/jlr.m800491-jlr200
Autor:
Vaishali Handa, Margaret C. Cam, Karen Usdin, George Poy, Deena Goldwater, Daman Kumari, David Stiles
Publikováno v:
FEBS Letters. 579:2702-2708
People with 59–200 CGG · CCG-repeats in the 5′ UTR of one of their FMR1 genes are at risk for Fragile X tremor and ataxia syndrome. Females are also at risk for premature ovarian failure. These symptoms are thought to be due to the presence of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09f50d2ae7cb62593b4ab850bab2fa7
https://doi.org/10.1016/j.febslet.2005.04.004
https://doi.org/10.1016/j.febslet.2005.04.004
Autor:
Zhirong Zhan, Paraskevi Giannakakou, Turid Knutsen, Tito Fojo, Mikhail V. Blagosklonny, George Poy
Publikováno v:
Oncogene. 19:3078-3085
The efficacy of anticancer therapy is limited by the development of drug resistance. While the role of p53 in the intrinsic sensitivity of human cancer cells to paclitaxel (PTX) remains controversial, its role in acquired paclitaxel resistance has ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dacc3ec5ec9a64c890495abd8611dc9f
https://doi.org/10.1038/sj.onc.1203642
https://doi.org/10.1038/sj.onc.1203642
Autor:
Karim Malik, Alan O. Perantoni, Ho-Shik Kim, George Poy, Sean Bong Lee, Anne L. Hancock, Margaret C. Cam, Jik Young Park, James Harper, Myoung Shin Kim
Publikováno v:
The Journal of biological chemistry. 282(22)
The Wilms' tumor suppressor gene (WT1) encodes a zinc finger transcription factor that is vital during development of several organs including metanephric kidneys. Despite the critical regulatory role of WT1, the pathways and mechanisms by which WT1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c58c4fa921289760eb387f53c7d032d
https://pubmed.ncbi.nlm.nih.gov/17430890
https://pubmed.ncbi.nlm.nih.gov/17430890
Publikováno v:
The FASEB Journal. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77f180cca5fbeba065dc61fdee90e37c
https://doi.org/10.1096/fasebj.21.6.lb77-c
https://doi.org/10.1096/fasebj.21.6.lb77-c
Mouse Sprr2 genes: a clustered family of genes showing differential expression in epithelial tissues
Autor:
Peter M. Steinert, Nadine Darwiche, George Poy, Toshio Kuroki, Hae Jun Song, Ulrike Lichti, Tonja Kartasova
Publikováno v:
Genomics. 55(1)
Small proline-rich (SPR) proteins are structural components of the cornified cell envelope of stratified squamous epithelia. They are subdivided into three families, i.e., SPR1, SPR2, and SPR3, of which the SPR2 family is the most complex. To underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56246f5d809761477eea085f8e4be0f7
https://pubmed.ncbi.nlm.nih.gov/9888996
https://pubmed.ncbi.nlm.nih.gov/9888996
Publikováno v:
Gene. 210(2)
The μ2 chain of the clathrin-associated adaptor complex AP-2 is a member of the adaptor medium chain family, a group of proteins involved in the sorting of integral membrane proteins in endocytic/exocytic pathways. Here, we report the cloning of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ebd2c201460485abff800079729e9b9
https://pubmed.ncbi.nlm.nih.gov/9573360
https://pubmed.ncbi.nlm.nih.gov/9573360
Autor:
Juan S. Bonifacino, Jorge E. Moreira, Chean Eng Ooi, George Poy, Esteban C. Dell'Angelica, David A. Wassarman
Publikováno v:
The EMBO journal. 16(15)
Drosophila eye pigmentation defects have thus far been attributed to mutations in genes encoding enzymes required for biosynthesis of pigments and to ABC-type membrane transporters for pigments or their precursors. We report here that a defect in a g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a540bfa53063eea1103959742e111065
https://pubmed.ncbi.nlm.nih.gov/9303295
https://pubmed.ncbi.nlm.nih.gov/9303295