Zobrazeno 1 - 4
of 4
pro vyhledávání: '"George Paloumbis"'
Autor:
Petros G. Tsoungas, Theodosia Maina, George Pairas, Christos Petrou, George Paloumbis, Paul Cordopatis, Berthold A. Nock
Publikováno v:
Synthesis. 2007:845-852
The synthesis of a suitably protected sugar amino acid (δ-glyco-amino acid) as a building block to be incorporated into the peptide chain (N-terminus) of bioactive peptide analogues is described. Its efficient coupling reactions with pilot amino aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9567c6f3bb3309ac0d0c2d66448ac14
https://doi.org/10.1055/s-2007-965942
https://doi.org/10.1055/s-2007-965942
Publikováno v:
Tetrahedron. 59:9349-9360
Stabilised tributylphosphonium ylids Bu3PCHCH(EWG), where EWG is CO2Me, CO2tBu or CN, react with protected sugar lactones under mild conditions to give high yields of glycosylidene derivatives ( 4 and 5 ) with good Z/E selectivity. X-Ray crystallo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a909b375a93c91979654e8af0aaa605
https://doi.org/10.1016/j.tet.2003.09.081
https://doi.org/10.1016/j.tet.2003.09.081
Autor:
Isabelle Lyothier, W. Lee, Alex Dyson, Andrew J. Davis, Mohammed Yaqoob, Glyn Hughes, Hart Terance William, Prafula Copp, Alyson Fox, Peter McIntyre, Stuart Bevan, Max-Peter Seiler, Martin Christiansen, Clive Gentry, Lee Edwards, Andrew James Culshaw, Allan Hallett, Sally Knights, Sadhana Patel, Clare Davis, Moh Panesar, Kaspar Zimmermann, George Paloumbis, Edward K. Dziadulewicz, Andrew McBryde, Hendrikus Eggelte, Alex Groarke, Peter Kotsonis
Publikováno v:
Journal of medicinal chemistry. 49(2)
Vanilloid receptor 1 (VR1, TRPV1) is a cation-selective ion channel that is expressed on primary afferent neurons and is upregulated following inflammation and nerve damage. Blockers of this channel may have utility in the treatment of chronic nocice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f4c25b4c9d539093bc540c900bdf7d
https://pubmed.ncbi.nlm.nih.gov/16420034
https://pubmed.ncbi.nlm.nih.gov/16420034