Zobrazeno 1 - 10
of 93
pro vyhledávání: '"George P. Giacoia"'
Publikováno v:
The Journal of Clinical Pharmacology. 62
Clinical pharmacology is a branch of the field of pharmacology that evolved following the recognition that the nature, duration, and intensity of drug action depend on both the intrinsic properties of the drug and an interaction with the host to whom
Autor:
George P. Giacoia, Aaron C. Pawlyk, Perdita Taylor-Zapata, Zhaoxia Ren, Margaret C. Grabb, Lesly Samedy-Bates
Publikováno v:
The Journal of Clinical Pharmacology. 61
Autor:
Yaning Wang, Lynne Yao, Issam Zineh, Aaron C. Pawlyk, Susan McCune, Gilbert J. Burckart, Shirley Seo, George P. Giacoia
Publikováno v:
Clin Pharmacol Ther
Understanding all aspects of developmental biology, or pediatric ontogeny, that affect drug therapy from the fetus to the adolescent child is the holy grail of pediatric scientists and clinical pharmacologists. The scientific community is now close t
Autor:
George P. Giacoia, Charlotte A. Pratt, Dionna J. Green, Mona Khurana, Anne Zajicek, Aaron S. Kelly, Stephen R. Daniels, Joseph T. Flynn, Jennifer S. Li, Gilbert J. Burckart, Perdita Taylor-Zapata, Carissa M. Baker-Smith, Elaine M. Urbina
Publikováno v:
Pediatrics
Hypertension affects >40% of the US population and is a major contributor to cardiovascular-related morbidity and mortality. Although less common among children and adolescents, hypertension affects 1% to 5% of all youth. The 2017 Clinical Practice G
Autor:
Janina Karres, William V. Tamborlane, Paula H. Hale, Kathleen E. Bethin, Rose Gubitosi-Klug, Jeffrey L. Blumer, George P. Giacoia, Georgeanna J. Klingensmith, Paolo Tomasi, Morey W. Haymond, Michael D. Reed, R. Ravi Shankar, Ingrid Libman, Ronald J. Portman, David B. Dunger
Publikováno v:
Diabetes Care. 39:323-329
The Best Pharmaceuticals for Children Act of 2002 mandated that the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) carries out critical reviews of the gaps in knowledge and unmet needs regarding safe and effec
Autor:
Daniel J. Jackson, Hengameh H. Raissy, Stanley J. Szefler, Wanda Phipatanakul, George P. Giacoia, James F. Chmiel, Heber C. Nielsen, Anne M. Fitzpatrick, Thomas P. Green
Publikováno v:
Journal of Allergy and Clinical Immunology. 133:3-13
The Eunice Kennedy Shriver National Institute of Child Health and Human Development convened an Asthma Group in response to the Best Pharmaceuticals for Children Act. The overall goal of the Best Pharmaceuticals for Children Act Program is to improve
Publikováno v:
Clinical Therapeutics. 34:S1-S10
Background The Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health (NIH) organized a workshop held in November 2011 to address knowledge gaps that limit the availability of adequate ped
Publikováno v:
Clinics in Perinatology. 39:11-23
Although some drugs have been developed for the neonate, drug development for the least mature and most vulnerable pediatric patients is lacking. Most of the drugs are off-label or off-patent and are empirically administered to newborns once efficacy
Publikováno v:
International Journal of Pharmaceutics; Vol 435
Excipients that are commonly used in adult medicines have been associated with elevated toxicological risks and safety issues in children. However, the information available on their acceptability for paediatric age groups is sparse and distributed o
Publikováno v:
Clinical Therapeutics. 30:2097-2101
Background: The Pediatric Formulation Initiative (PFI) is a project of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The PFI was established to address the issue of the lack of appropriate formulations i