Zobrazeno 1 - 10
of 66
pro vyhledávání: '"George P. Anderson"'
Autor:
Jinny L. Liu, Dan Zabetakis, Lisa C. Shriver‐Lake, George P. Anderson, Ellen R. Goldman, Hieu Bui
Publikováno v:
Advanced Sensor Research, Vol 3, Iss 2, Pp n/a-n/a (2024)
Abstract Immunoassays are widely used in various fields, including biomedical research, clinical diagnostics, and environmental monitoring. Single domain antibodies (sdAbs) provide small, tailorable, recognition elements that have been integrated int
Externí odkaz:
https://doaj.org/article/d27f156a06754ef598f1f8df58b18c1b
Autor:
Jinny L. Liu, Dan Zabetakis, Christina L. Gardner, Crystal W. Burke, Pamela J. Glass, Emily M. Webb, Lisa C. Shriver-Lake, George P. Anderson, James Weger-Lucarelli, Ellen R. Goldman
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Venezuelan equine encephalitis virus (VEEV) is a mosquito borne alphavirus which leads to high viremia in equines followed by lethal encephalitis and lateral spread to humans. In addition to naturally occurring outbreaks, VEEV is a potential
Externí odkaz:
https://doaj.org/article/2c70083720fb45b09c0986debbe9c28b
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract There are currently few approved effective treatments for SARS-CoV-2, the virus responsible for the COVID-19 pandemic. Nanobodies are 12–15 kDa single-domain antibody fragments that can be delivered by inhalation and are amenable to relati
Externí odkaz:
https://doaj.org/article/781613999e5f4819ab8747154b1624dd
Publikováno v:
Antibodies, Vol 11, Iss 4, p 64 (2022)
Single domain antibodies (sdAb) are the recombinant variable heavy domains derived from camelid heavy-chain antibodies. While they have binding affinities equivalent to conventional antibodies, sdAb are only one-tenth the size and possess numerous ad
Externí odkaz:
https://doaj.org/article/ace5c24d308343029613054174d71958
Autor:
Mark A. Olson, Patricia M. Legler, Daniel Zabetakis, Kendrick B. Turner, George P. Anderson, Ellen R. Goldman
Publikováno v:
ACS Omega, Vol 4, Iss 6, Pp 10444-10454 (2019)
Externí odkaz:
https://doaj.org/article/2fd1f0a3c5db41f2bc17a00e8a0ad532
Autor:
Jinny L. Liu, Emily M. Webb, Dan Zabetakis, Crystal W. Burke, Christina L. Gardner, Pamela J. Glass, Patricia M. Legler, James Weger-Lucarelli, George P. Anderson, Ellen R. Goldman
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
A single domain antibody (clone CC3) previously found to neutralize a vaccine strain of the chikungunya virus (PRNT50 = 2. 5 ng/mL) was found to be broadly neutralizing. Clone CC3 is not only able to neutralize a wild-type (WT) strain of chikungunya
Externí odkaz:
https://doaj.org/article/29c401c161464a698b0ccea2b029bfa3
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Over the past two decades, various scaffolds have been designed and synthesized to organize enzyme cascades spatially for enhanced enzyme activity based on the concepts of substrate channeling and enhanced stability. The most bio-compatible synthetic
Externí odkaz:
https://doaj.org/article/b50503c836f4463cb6cfff0e9e18ae9c
Publikováno v:
ACS Omega, Vol 3, Iss 5, Pp 4810-4815 (2018)
Externí odkaz:
https://doaj.org/article/1fca4c6f421b4aa6b358ea6e0dc1b2e5
Publikováno v:
Microbial Cell Factories, Vol 16, Iss 1, Pp 1-12 (2017)
Abstract Background A key advantage of recombinant antibody technology is the ability to optimize and tailor reagents. Single domain antibodies (sdAbs), the recombinantly produced variable domains derived from camelid and shark heavy chain antibodies
Externí odkaz:
https://doaj.org/article/c0aec0175f5244dbaedb21528126cd64
Publikováno v:
Antibodies, Vol 9, Iss 4, p 71 (2020)
Lassa virus is the etiologic agent of Lassa fever, an acute and often fatal illness endemic to West Africa. It is important to develop new reagents applicable either for the specific diagnosis or as improved therapeutics for the treatment of Lassa fe
Externí odkaz:
https://doaj.org/article/51b76dd18ae6438bb951bdf789731e2a