Zobrazeno 1 - 10
of 112
pro vyhledávání: '"George P Stathopoulos"'
Autor:
Marta Dueñas, Mirentxu Santos, Juan F Aranda, Concha Bielza, Ana B Martínez-Cruz, Corina Lorz, Miquel Taron, Eva M Ciruelos, José L Rodríguez-Peralto, Miguel Martín, Pedro Larrañaga, Jubrail Dahabreh, George P Stathopoulos, Rafael Rosell, Jesús M Paramio, Ramón García-Escudero
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42494 (2012)
Mutations in the TP53 gene are very common in human cancers, and are associated with poor clinical outcome. Transgenic mouse models lacking the Trp53 gene or that express mutant Trp53 transgenes produce tumours with malignant features in many organs.
Externí odkaz:
https://doaj.org/article/aa4b88e29f75412e9bf812a4c6c27a2d
Autor:
Kyriakos Orfanakos, Aristina Papanota, George P. Stathopoulos, Constantinos Alifieris, Nikolaos M. Sitaras, Dimitrios T. Trafalis
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 143:717-725
This is a single-center uncontrolled retrospective study to evaluate the efficacy and safety of the biosimilar epoetin zeta after approval in chemotherapy-induced anemia (CIA). Patients screened were >18 years old suffering from solid malignancies an
Publikováno v:
Cancer Chemotherapy and Pharmacology. 77:713-722
This phase II study investigates the efficacy and safety of DNA topoisomerase I inhibitor irinotecan plus bevacizumab a monoclonal antibody against VEGF (BEVIRI) in patients with relapsed chemo-resistant SCLC. Patients who previously completed treatm
Autor:
Maria Kaparelou, Sotirios Rigatos, Athanasios Polychronis, Photini Antoniou, Athanasios Armakolas, Christos Markopoulos, George P. Stathopoulos, Nikolaos A. Malamos, Anna Yannopoulou
Publikováno v:
Anti-Cancer Drugs
Supplemental Digital Content is available in the text.
The Ki-67 antigen was identified in the early steps of polymerase I-dependent ribosomal RNA synthesis. Although it seems that this protein has an important function in cell division, its exa
The Ki-67 antigen was identified in the early steps of polymerase I-dependent ribosomal RNA synthesis. Although it seems that this protein has an important function in cell division, its exa
Publikováno v:
Journal of B.U.ON. : official journal of the Balkan Union of Oncology. 21(4)
Bone metastases in breast cancer are quite common, and some patients may have no other site of metastasis. An effective treatment is often endocrine agents administration (tamoxifen or antiaromatases), given mainly to postmenopausal women. Radiation
Autor:
Michael Koutsilieris, Adrianos Nezos, George P. Stathopoulos, Martha Stathaki, Apostolos Theos, Athanasios Armakolas
Publikováno v:
Oncology Reports. 28:2255-2263
Gene expression patterns as well as gene interactions are under investigation for their involvement in tumour heterogeneity. The molecular classification of breast cancer based on hormone receptor expression, grade and HER2 receptor levels, is indica
Autor:
Teni Boulikas, George P. Stathopoulos
Publikováno v:
Journal of Drug Delivery, Vol 2012 (2012)
Journal of Drug Delivery
Journal of Drug Delivery
Patented platform technologies have been used for the liposomal encapsulation of cisplatin (Lipoplatin) into tumor-targeted 110 nm (in diameter) nanoparticles. The molecular mechanisms, preclinical and clinical data concerning lipoplatin, are reviewe
Publikováno v:
Oncology Letters. 4:1013-1016
Liposomal cisplatin (Lipoplatin) is a new agent, a cisplatin formulation that has been investigated in a number of studies and compared with cisplatin with respect to toxicity and effectiveness. It has been administered once weekly and in combination
Autor:
J. Dimitroulis, George P. Stathopoulos, K. Marosis, D. Antoniou, P. Michalopoulou, J. Stathopoulos
Publikováno v:
Cancer Chemotherapy and Pharmacology
Purpose Liposomal cisplatin was developed to reduce the systemic toxicity of cisplatin, particularly the nephrotoxicity, and it has been used in combination with other agents in pancreatic and head and neck cancers and non-small-cell lung cancer (NSC
Autor:
J. Stathopoulos, J. Legakis, S. Batzios, Dimitrios T. Trafalis, C. Batziou, Athanasios Armakolas, J. Koutantos, George P. Stathopoulos
Publikováno v:
Oncology. 78:376-381
Objective: The objective of this phase III trial was to compare chemotherapy combined with bevacizumab versus chemotherapy alone in the treatment of patients with advanced colorectal cancer. Methods: From September 2004 till September 2008, 222 treat