Zobrazeno 1 - 10
of 469
pro vyhledávání: '"George P Patrinos"'
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0267095 (2022)
MotivationThe outbreak of coronavirus health issues caused by COVID-19(SARS-CoV-2) creates a global threat to public health. Therefore, there is a need for effective remedial measures using existing and approved therapies with proven safety measures
Externí odkaz:
https://doaj.org/article/835698a2043e451bae2ed99adff7543c
Autor:
Kathrin Blagec, Jesse J Swen, Rudolf Koopmann, Ka-Chun Cheung, Mandy Crommentuijn-van Rhenen, Inge Holsappel, Lidija Konta, Simon Ott, Daniela Steinberger, Hong Xu, Erika Cecchin, Vita Dolžan, Cristina Lucía Dávila-Fajardo, George P Patrinos, Gere Sunder-Plassmann, Richard M Turner, Munir Pirmohamed, Henk-Jan Guchelaar, Matthias Samwald, Ubiquitous Pharmacogenomics Consortium
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0268534 (2022)
BackgroundThe clinical implementation of pharmacogenomics (PGx) could be one of the first milestones towards realizing personalized medicine in routine care. However, its widespread adoption requires the availability of suitable clinical decision sup
Externí odkaz:
https://doaj.org/article/cf3de4b33c1c49618c5a84098ee237ef
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 12, p e1005832 (2017)
Externí odkaz:
https://doaj.org/article/e2f81ff335384b5ab9dbbb51cbeb707a
Autor:
Clint Mizzi, Eleni Dalabira, Judit Kumuthini, Nduna Dzimiri, Istvan Balogh, Nazli Başak, Ruwen Böhm, Joseph Borg, Paola Borgiani, Nada Bozina, Henrike Bruckmueller, Beata Burzynska, Angel Carracedo, Ingolf Cascorbi, Constantinos Deltas, Vita Dolzan, Anthony Fenech, Godfrey Grech, Vytautas Kasiulevicius, Ľudevít Kádaši, Vaidutis Kučinskas, Elza Khusnutdinova, Yiannis L Loukas, Milan Macek, Halyna Makukh, Ron Mathijssen, Konstantinos Mitropoulos, Christina Mitropoulou, Giuseppe Novelli, Ioanna Papantoni, Sonja Pavlovic, Giuseppe Saglio, Jadranka Sertić, Maja Stojiljkovic, Andrew P Stubbs, Alessio Squassina, Maria Torres, Marek Turnovec, Ron H van Schaik, Konstantinos Voskarides, Salma M Wakil, Anneke Werk, Maria Del Zompo, Branka Zukic, Theodora Katsila, Ming Ta Michael Lee, Alison Motsinger-Rief, Howard L Mc Leod, Peter J van der Spek, George P Patrinos
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172595 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0162866.].
Externí odkaz:
https://doaj.org/article/bfb926067d6344b3b90c530f5e7e1bb4
Autor:
Kleanthi Lakiotaki, Alexandros Kanterakis, Evgenia Kartsaki, Theodora Katsila, George P Patrinos, George Potamias
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182138 (2017)
Racial and ethnic differences in drug responses are now well studied and documented. Pharmacogenomics research seeks to unravel the genetic underpinnings of inter-individual variability with the aim of tailored-made theranostics and therapeutics. Tak
Externí odkaz:
https://doaj.org/article/1b496cc3f02740faa2b102ece052f902
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-12 (2024)
Abstract Background Pharmacogenomics (PGx) constitutes an important part of personalized medicine and has several clinical applications. PGx role in clinical practice is known, however, it has not been widely adopted yet. In this study, we aim to inv
Externí odkaz:
https://doaj.org/article/0bd756be6a074bee98c3522d7449141a
Autor:
Theodora Chatzilygeroudi, Vasiliki Chondrou, Ruben Boers, Stavroula Siamoglou, Katerina Athanasopoulou, Evgenia Verigou, Joost Gribnau, Spyridon Alexis, Vassiliki Labropoulou, Alexandra Kourakli, George P. Patrinos, Argyro Sgourou, Argiris Symeonidis
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background As new treatment options for patients with higher-risk myelodysplastic syndromes are emerging, identification of prognostic markers for hypomethylating agent (HMA) treatment and understanding mechanisms of their delayed and short-
Externí odkaz:
https://doaj.org/article/37ed50421950464dab8771db4a51cff6
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Nowadays, we are experiencing the big data era with the emerging challenge of single data interpretation. Although the advent of high-throughput technologies as well as chemo- and bio- informatics tools presents pan-omics data as the way forward to p
Externí odkaz:
https://doaj.org/article/5177996d25b94e0e904bdb4c847448ff
Autor:
Clint Mizzi, Eleni Dalabira, Judit Kumuthini, Nduna Dzimiri, Istvan Balogh, Nazli Başak, Ruwen Böhm, Joseph Borg, Paola Borgiani, Nada Bozina, Henrike Bruckmueller, Beata Burzynska, Angel Carracedo, Ingolf Cascorbi, Constantinos Deltas, Vita Dolzan, Anthony Fenech, Godfrey Grech, Vytautas Kasiulevicius, Ľudevít Kádaši, Vaidutis Kučinskas, Elza Khusnutdinova, Yiannis L Loukas, Milan Macek, Halyna Makukh, Ron Mathijssen, Konstantinos Mitropoulos, Christina Mitropoulou, Giuseppe Novelli, Ioanna Papantoni, Sonja Pavlovic, Giuseppe Saglio, Jadranka Setric, Maja Stojiljkovic, Andrew P Stubbs, Alessio Squassina, Maria Torres, Marek Turnovec, Ron H van Schaik, Konstantinos Voskarides, Salma M Wakil, Anneke Werk, Maria Del Zompo, Branka Zukic, Theodora Katsila, Ming Ta Michael Lee, Alison Motsinger-Rief, Howard L Mc Leod, Peter J van der Spek, George P Patrinos
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162866 (2016)
Pharmacogenomics aims to correlate inter-individual differences of drug efficacy and/or toxicity with the underlying genetic composition, particularly in genes encoding for protein factors and enzymes involved in drug metabolism and transport. In sev
Externí odkaz:
https://doaj.org/article/65d317caa72545be89067d0f39dc3afe
Autor:
Kleanthi Lakiotaki, Evgenia Kartsaki, Alexandros Kanterakis, Theodora Katsila, George P Patrinos, George Potamias
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162801 (2016)
One of the challenges that arise from the advent of personal genomics services is to efficiently couple individual data with state of the art Pharmacogenomics (PGx) knowledge. Existing services are limited to either providing static views of PGx vari
Externí odkaz:
https://doaj.org/article/382791d487e14678ab0a8249ea057c1c