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Publikováno v:
The journal of applied laboratory medicine. 1(6)
Two of the most significant individuals in the recent history of clinical chemistry have died. George N. Bowers, Jr., MD, 89, died on August 16, 2015 (1), and Robert B. McComb, PhD, 89, died on January 22, 2016 (2). George and Bob formed a unique par
There can be no doubt that alkaline phosphatase is one of the most extensively in vestigated of all enzymes. This has resulted from the ubiquity of its distribution, and from the ease and sensitivity with which its activity can be measured. Unfortu
Publikováno v:
Clinical Chemistry. 41:1306-1312
The issuance of cholesterol as a Standard Reference Material (SRM) in 1967 started the National Institute of Standards and Technology (NIST; then named the National Bureau of Standards) on a major effort to help clinical laboratories establish and im
Publikováno v:
Clinical Chemistry. 38:2286-2294
We evaluated N-methyl-D-glucamine (MEG) as a buffer for assay of alkaline phosphatase (ALP; EC 3.1.3.1) and compared the MEG-based assay with the current International Federation of Clinical Chemistry Reference Method for ALP (IFCC/RM/ALP), in which
Publikováno v:
Clinical Chemistry. 36:1789-1792
The manual Reference Method of the Centers for Disease Control for serum iron (CDC/RM/Fe) and a semiautomated adaptation of it were used to evaluate two working methods: one, a detergent solubilization procedure for the Roche Cobas-Bio analyzer, the
Autor:
George N. Bowers, Mary Onoroski
Publikováno v:
Clinical Chemistry. 36:1399-1403
Publikováno v:
Clinical Chemistry. 36:104-110
Ion-selective electrode analyzers for measuring lithium (Li/ISE) in serum became available in early 1987. We compared results for patients' samples from three of them vs results from flame atomic emission spectrometry (FAES). Within-run and day-to-da
Autor:
Alan H.B. Wu, Sidney M. Hopfer, George N. Bowers, Gregory S. Makowski, Charles A McKay, Katherine Kelly, Jason Vena, Elaine Forte, Andrew Smith, Herbert Malkus, John McDonagh, Salvatore F. Sena, Robert B. McComb
Publikováno v:
Clinical toxicology (Philadelphia, Pa.). 46(2)
Hospital laboratories currently lack the capacity to provide emergency determination of cholinesterase activity.We have developed a hospital-based 3-tiered system to test plasma for butyrylcholinesterase (BChE) activity and whole blood for red cell a
Autor:
George N. Bowers
Publikováno v:
Clinical Chemistry. 47:611-612
The first book, Dates in Medicine: A Chronological Record of Medical Progress over Three Millennia , is a collection of “important milestones in the development—since antiquity—of modern medicine”. It is a massive listing of approximately 600