Zobrazeno 1 - 10
of 146
pro vyhledávání: '"George N, Tzanakakis"'
Autor:
Rafaela-Maria Kavasi, Monica Neagu, Carolina Constantin, Adriana Munteanu, Mihaela Surcel, Aristidis Tsatsakis, George N. Tzanakakis, Dragana Nikitovic
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), referred to as keratinocyte carcinomas, are skin cancer with the highest incidence. BCCs, rarely metastasize; whereas, though generally not characterized by high lethality, appr
Externí odkaz:
https://doaj.org/article/d2ccc85925804543a3948284bda61fdc
Autor:
Eirini-Maria Giatagana, Aikaterini Berdiaki, Aristidis Tsatsakis, George N. Tzanakakis, Dragana Nikitovic
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1319 (2021)
Carcinogenesis is a multifactorial process with the input and interactions of environmental, genetic, and metabolic factors. During cancer development, a significant remodeling of the extracellular matrix (ECM) is evident. Proteoglycans (PGs), such a
Externí odkaz:
https://doaj.org/article/2511a828e57444eab9439b93aa6d4033
Autor:
Aikaterini Berdiaki, Monica Neagu, Eirini-Maria Giatagana, Andrey Kuskov, Aristidis M. Tsatsakis, George N. Tzanakakis, Dragana Nikitovic
Publikováno v:
Biomolecules, Vol 11, Iss 3, p 395 (2021)
The tumor microenvironment (TME) is composed of cancerous, non-cancerous, stromal, and immune cells that are surrounded by the components of the extracellular matrix (ECM). Glycosaminoglycans (GAGs), natural biomacromolecules, essential ECM, and cell
Externí odkaz:
https://doaj.org/article/c0158464589145c99a01604c3ad3dc54
Autor:
Kallirroi Voudouri, Dragana Nikitovic, Aikaterini Berdiaki, John Tsiaoussis, Dimitris Kletsas, Nikos K. Karamanos, George N. Tzanakakis
Publikováno v:
Data in Brief, Vol 9, Iss C, Pp 568-572 (2016)
In this data article, the potential role of p53 tumor suppressor gene (p53) on the attachment ability of MCF-7 breast cancer cells was investigated. In our main article, “IGF-I/ EGF and E2 signaling crosstalk through IGF-IR conduit point affect bre
Externí odkaz:
https://doaj.org/article/ce31f68678364e95adc7b39f47ae46c4
Autor:
John Aggelidakis, Aikaterini Berdiaki, Dragana Nikitovic, Antonis Papoutsidakis, Dionysios J. Papachristou, Aristidis M. Tsatsakis, George N. Tzanakakis
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Biglycan, a small leucine rich proteoglycan (SLRP), is an important participant in bone homeostasis and development as well as in bone pathology. In the present study biglycan was identified as a positive regulator of MG63 osteosarcoma cell growth (p
Externí odkaz:
https://doaj.org/article/6b3328d21b694adeaa5823907cd859ee
Autor:
Dragana Nikitovic, Aikaterini Berdiaki, Ioanna Spyridaki, Theodoros Krasanakis, Aristidis Tsatsakis, George N. Tzanakakis
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Proteoglycans (PGs), important constituents of the extracellular matrix, have been associated with cancer pathogenesis. Their unique structure consisting of a protein core and glycosaminoglycan chains endowed with fine modifications constitutes these
Externí odkaz:
https://doaj.org/article/846f6a54994e4b7a87ac6895b9dd42ff
Autor:
Aristidis Tsatsakis, Polychronis Stivaktakis, Dragana Nikitovic, Antonios Stratidakis, Emmanouela Perisynaki, Mikhail M Shtilman, A. N. Kuskov, Petra Henrich-Noack, Anna L. Luss, Aikaterini Berdiaki, George N. Tzanakakis, Pavel P. Kulikov
Publikováno v:
Molecular Pharmaceutics. 17:4212-4225
Nanoparticles (NPs) produced from amphiphilic derivatives of poly-N-vinylpyrrolidone (Amph-PVP), composed of various molecular weight polymeric hydrophilic fragments linked into hydrophobic n-alkyl chains of varying lengths, were previously shown to
Autor:
Eirini Maria Giatagana, George N. Tzanakakis, Aristidis Tsatsakis, Dragana Nikitovic, Aikaterini Berdiaki, Antonis Papoutsidakis, Demetrios A. Spandidos, Ioanna Spyridaki
Publikováno v:
International Journal of Oncology
Chondrosarcoma is a malignant bone tumor characterized by the production of a modified cartilage‑type extracellular matrix (ECM). In the present study, the expression levels of the small leucine‑rich proteoglycans (SLRPs), decorin, biglycan and l
Autor:
Eirini-Maria Giatagana, Aikaterini Berdiaki, Margrethe Gaardløs, Sergey A. Samsonov, George N. Tzanakakis, Dragana Nikitovic
Publikováno v:
Cancers; Volume 14; Issue 5; Pages: 1196
Osteosarcoma (OS) is a mesenchymally derived, aggressive bone cancer. OS cells produce an aberrant nonmineralized or partly mineralized extracellular matrix (ECM) whose components participate in signaling pathways connected to specific pathogenic phe
Autor:
Alexandros Zafiropoulos, Manolis Linardakis, Eugene H.J.M. Jansen, Aristidis M. Tsatsakis, Antonis Kafatos, George N. Tzanakakis
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 7, Pp 1991-2000 (2010)
Serum paraoxonase 1 (PON1) function has been associated with human cardiovascular disease. The projected mechanism postulates interaction of PON1 with lipoproteins and insulin signaling resulting in alterations in lipid homeostasis. Recently, PON2 wa
Externí odkaz:
https://doaj.org/article/70eeb7a0dfc74db8a2612041d9c5fecb