Výsledky vyhledávání - "George N, Lambrou"

Visual acuity time in range: a novel concept to describe consistency in treatment response in diabetic macular oedema

Autor: Igor Kozak, Ian Pearce, Chui Ming Gemmy Cheung, Tobias Machewitz, George N. Lambrou, Daniel Molina, Lima Suleiman, Hossam Youssef, Neil M. Bressler

Publikováno v: Eye.

Objective To assess ‘time in range’ as a novel measure of treatment response in diabetic macular oedema (DMO). Methods This post hoc analysis of the Protocol T randomised clinical trial included 660 individuals with centre-involved DMO and best-c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb03ca6ab25c13a696fd4912393789ee
https://doi.org/10.1038/s41433-023-02507-x

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EFFICACY AND SAFETY OF INTRAVITREAL AFLIBERCEPT USING A TREAT-AND-EXTEND REGIMEN FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

Autor: Thomas Schmelter, Edoardo Midena, Paul Mitchell, Helmut Allmeier, Frank G. Holz, Philip G Hykin, Aries study investigators, Sebastian Wolf, George N. Lambrou, Eric H Souied

Publikováno v: Retina. 41:1911-1920

Treating neovascular age-related macular degeneration with intravitreal aflibercept treat-and-extend (TE) can reduce treatment burden. ARIES assessed whether intravitreal aflibercept early-start TE was noninferior to late-start TE.A randomized, open-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88378a34e769468f1010aa26e9db89b2
https://doi.org/10.1097/iae.0000000000003128

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Akademický článek

Epidemiological and Clinical Baseline Characteristics as Predictive Biomarkers of Response to Anti-VEGF Treatment in Patients with Neovascular AMD

Autor: Miltiadis K. Tsilimbaris, Maria I. López-Gálvez, Roberto Gallego-Pinazo, Philippe Margaron, George N. Lambrou

Publikováno v: Journal of Ophthalmology, Vol 2016 (2016)

Purpose. To review the current literature investigating patient response to antivascular endothelial growth factor-A (VEGF) therapy in the treatment of neovascular age-related macular degeneration (nAMD) and to identify baseline characteristics that

Externí odkaz: https://doaj.org/article/0c2fa293fbe3434fa834ec45d25d16e1

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Anti-VEGF intravitreal injections in the era of COVID-19: responding to different levels of epidemic pressure

Autor: Ian Pearce, Monica Lövestam-Adrian, Rafael Navarro, Paolo Lanzetta, Francisco Rodríguez, David T. Wong, Anat Loewenstein, Annabelle A. Okada, Jean-François Korobelnik, Bora Eldem, Adrian Koh, Antonia M. Joussen, George N. Lambrou, Lihteh Wu, Xiaoxin Li

Publikováno v: Graefes Archive for Clinical and Experimental Ophthalmology
Graefe's Archive for Clinical and Experimental Ophthalmology
Graefe's Archive for Clinical and Experimental Ophthalmology, Springer Verlag, 2021, 259 (3), pp.567-574. ⟨10.1007/s00417-021-05097-0⟩

Purpose Following the first wave of the COVID-19 pandemic in early 2020, the easing of strict measures to reduce its spread has led to a resurgence of cases in many countries at both the national and local level. This article addresses how guidance f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e79f8961f3a5e815b754f41594b4fce8

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VEGFR1 signaling in retinal angiogenesis and microinflammation

Autor: Patricia A. D'Amore, Marcus Fruttiger, Sandro De Falco, George N. Lambrou, Antonia M. Joussen, Florian Sennlaub, Kay D. Rittenhouse, Akiyoshi Uemura, Thomas Langmann, K. T. M. Johnson, Lynne R. Brunck

Publikováno v: Progress in retinal and eye research
Progress in Retinal and Eye Research
Progress in Retinal and Eye Research, Elsevier, 2021, pp.100954. ⟨10.1016/j.preteyeres.2021.100954⟩
Progress in retinal and eye research (Online) 84 (2021). doi:10.1016/j.preteyeres.2021.100954
info:cnr-pdr/source/autori:Uemura A.; Fruttiger M.; D'Amore P.A.; De Falco S.; Joussen A.M.; Sennlaub F.; Brunck L.R.; Johnson K.T.; Lambrou G.N.; Rittenhouse K.D.; Langmann T./titolo:VEGFR1 signaling in retinal angiogenesis and microinflammation/doi:10.1016%2Fj.preteyeres.2021.100954/rivista:Progress in retinal and eye research (Online)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:84

International audience; Five vascular endothelial growth factor receptor (VEGFR) ligands (VEGF-A, -B, -C, -D, and placental growth factor [PlGF]) constitute the VEGF family. VEGF-A binds to VEGF receptors 1 and 2 (VEGFR1/2), whereas VEGF-B and PlGF o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28cf50b943033af2d4bead6f51ccf98e
https://pubmed.ncbi.nlm.nih.gov/33640465

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Guidance for anti-VEGF intravitreal injections during the COVID-19 pandemic

Autor: Monica Lövestam-Adrian, Rafael Navarro, Paolo Lanzetta, Annabelle A. Okada, Ian Pearce, Adrian Koh, George N. Lambrou, Francisco Rodríguez, Xiaoxin Li, Lihteh Wu, Bora Eldem, Antonia M. Joussen, Jean-François Korobelnik, Anat Loewenstein, David T. Wong

Publikováno v: Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
Graefes Archive for Clinical and Experimental Ophthalmology

Purpose There is an urgent need to address how to best provide ophthalmic care for patients with retinal disease receiving intravitreal injections with anti-vascular endothelial growth factor agents during the ongoing global COVID-19 pandemic. This a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e97e37499af6914d901aacf71305f1b
http://hdl.handle.net/20.500.12278/26073

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SUSPENDING TREATMENT OF NEOVASCULAR AGE-RELATED MACULAR DEGENERATION IN CASES OF FUTILITY

Autor: David T. Wong, Ian Pearce, George N. Lambrou, Annabelle A. Okada, Anat Loewenstein

Publikováno v: Retina (Philadelphia, Pa.)

This publication summarizes the recommendations of the Vision Academy Steering Committee for the management of neovascular age-related macular degeneration in patients with poor response to anti–vascular endothelial growth factor therapy, consideri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045fcc8f644ca29820d6645793553683
https://pubmed.ncbi.nlm.nih.gov/31876889

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Genetic predictive biomarkers of anti-VEGF treatment response in patients with neovascular age-related macular degeneration

Autor: George N. Lambrou, Sascha Fauser

Publikováno v: Survey of Ophthalmology. 60:138-152

Anti-vascular endothelial growth factor (anti-VEGF) therapies for neovascular age-related macular degeneration (nAMD) have proven efficacy at a study-population level, although individual patient responses vary, with most of the patients responding w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a891e5b4cf0a2df96f9172d1a9f3b4
https://doi.org/10.1016/j.survophthal.2014.11.002

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Endothelin-1, nitric oxide, and glutamate in the normal and glaucomatous dog eye

Autor: Dennis Brooks, Maria E. Kallberg, Gustavo A. García-Sánchez, Nancy J. Szabo, Kirk N. Gelatt, George N. Lambrou

Publikováno v: Veterinary Ophthalmology. 10:46-52

Purpose To document differences in the levels of the endothelin-1 peptide, nitric oxide, and glutamate in aqueous humor and vitreous in the dog eye with spontaneous glaucoma compared to the normal dog eye. Methods Samples of aqueous humor and vitreou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5b55a6a24389b47d82d1ab6da191dd
https://doi.org/10.1111/j.1463-5224.2007.00529.x

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FTY720 sustains and restores neuronal function in the DA rat model of MOG-induced experimental autoimmune encephalomyelitis

Autor: Maria K. Storch, Robert Weissert, Balázs Balatoni, Peter Hiestand, Eva-M. Swoboda, Carolyn A. Foster, Agnieszka Koziel, Vinzenz Schönborn, George N. Lambrou

Publikováno v: Brain Research Bulletin. 74:307-316

FTY720 (fingolimod) is an oral sphingosine 1-phosphate (S1P) receptor modulator under development for the treatment of multiple sclerosis (MS). To elucidate its effects in the central nervous system (CNS), we compared functional parameters of nerve c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a4b57de993f0ae1233289c29763440
https://doi.org/10.1016/j.brainresbull.2007.06.023

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