Zobrazeno 1 - 10
of 67
pro vyhledávání: '"George Murphy"'
Autor:
Ashley Cornett, Harleen K. Athwal, Emily Hill, George Murphy, III, Kenji Yeoh, Christopher A. Moskaluk, Robert L. Witt, Nisha J. D'Silva, Seema Agarwal, Isabelle M.A. Lombaert
Publikováno v:
EBioMedicine, Vol 41, Iss , Pp 175-184 (2019)
Background: Patient-derived xenograft (PDX) models have significantly enhanced cancer research, and often serve as a robust model. However, enhanced growth rate and altered pathological phenotype with serial passages have repeatedly been shown in ade
Externí odkaz:
https://doaj.org/article/7a2e296f7a9843ca91f9208094a03260
Autor:
Harleen K. Athwal, George Murphy, III, Ellis Tibbs, Ashley Cornett, Emily Hill, Kenji Yeoh, Elsa Berenstein, Matthew P. Hoffman, Isabelle M.A. Lombaert
Publikováno v:
Stem Cell Reports, Vol 12, Iss 2, Pp 366-380 (2019)
Summary: Understanding how epithelial progenitors within exocrine glands establish specific cell lineages and form complex functional secretory units is vital for organ regeneration. Here we identify the transcription factor Sox10 as essential for bo
Externí odkaz:
https://doaj.org/article/9d887eff5421431c87e7264a1fe48bf6
Autor:
Kanika Kanchan, Kruthika Iyer, Lisa R Yanek, Ivan Carcamo-Orive, Margaret A Taub, Claire Malley, Kristin Baldwin, Lewis C Becker, Ulrich Broeckel, Linzhao Cheng, Chad Cowan, Matteo D'Antonio, Kelly A Frazer, Thomas Quertermous, Gustavo Mostoslavsky, George Murphy, Marlene Rabinovitch, Daniel J Rader, Martin H Steinberg, Eric Topol, Wenli Yang, Joshua W Knowles, Cashell E Jaquish, Ingo Ruczinski, Rasika A Mathias
Publikováno v:
Stem Cell Research, Vol 46, Iss , Pp 101803- (2020)
Human induced pluripotent stem cell (hiPSC) lines have previously been generated through the NHLBI sponsored NextGen program at nine individual study sites. Here, we examined the structural integrity of 506 hiPSC lines as determined by copy number va
Externí odkaz:
https://doaj.org/article/67a1f93cf892404e97877984f372295c
Autor:
Carl Ward, Giacomo Volpe, Pierre Cauchy, Anetta Ptasinska, Ruba Almaghrabi, Daniel Blakemore, Monica Nafria, Doris Kestner, Jon Frampton, George Murphy, Yosef Buganim, Keisuke Kaji, Paloma García
Publikováno v:
Cell Reports, Vol 24, Iss 6, Pp 1496-1511.e8 (2018)
Summary: During somatic reprogramming, Yamanaka’s pioneer factors regulate a complex sequence of molecular events leading to the activation of a network of pluripotency factors, ultimately resulting in the acquisition and maintenance of a pluripote
Externí odkaz:
https://doaj.org/article/a18ab7e136ff4233bfc83f272e0f8a76
Autor:
Rahul Purwar, James Campbell, George Murphy, William G Richards, Rachael A Clark, Thomas S Kupper
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16245 (2011)
Recent studies have shown that tissue resident memory T cells (T(RM)) are critical to antiviral host defense in peripheral tissues. This new appreciation of T(RM) that reside in epithelial tissues and mediate host defense has been studied most extens
Externí odkaz:
https://doaj.org/article/a71c15ed6e4946d58adcfd0fb18d3e24
Autor:
Sydney X Lu, Lucy W Kappel, Anne-Marie Charbonneau-Allard, Renée Atallah, Amanda M Holland, Claire Turbide, Vanessa M Hubbard, Jimmy A Rotolo, Marsinay Smith, David Suh, Christopher King, Uttam K Rao, Nury Yim, Johanne L Bautista, Robert R Jenq, Olaf Penack, Il-Kang Na, Chen Liu, George Murphy, Onder Alpdogan, Richard S Blumberg, Fernando Macian, Kathryn V Holmes, Nicole Beauchemin, Marcel R M van den Brink
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21611 (2011)
Allogeneic bone marrow transplantation (allo-BMT) is a potentially curative therapy for a variety of hematologic diseases, but benefits, including graft-versus-tumor (GVT) activity are limited by graft-versus-host-disease (GVHD). Carcinoembryonic ant
Externí odkaz:
https://doaj.org/article/21a1cc5de81c4f2eb8783a27b6d7db01
Autor:
F. Stephen Hodi, Margaret Shipp, Scott Rodig, Glenn Dranoff, Matthias Piesche, Jun Zhou, George Murphy, David McDermott, Donald Lawrence, Anita Giobbie-Hurder, Jing Ouyang, Xiaoyun Liao, Erin M. Connolly, Jingjing Li, Xinqi Wu
Supplementary Figure S1. Gal-1 antibodies were identified in the posttreatment plasma samples from melanoma patients on Ipi-Bev and pembrolizumab treatment. Supplementary Figure S2. Gal-1 antibody titers in pretreatment and posttreatment plasma sampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d34d5f9f432e145528a3c3e888c24af
https://doi.org/10.1158/2326-6066.22537955
https://doi.org/10.1158/2326-6066.22537955
Autor:
F. Stephen Hodi, Margaret Shipp, Scott Rodig, Glenn Dranoff, Matthias Piesche, Jun Zhou, George Murphy, David McDermott, Donald Lawrence, Anita Giobbie-Hurder, Jing Ouyang, Xiaoyun Liao, Erin M. Connolly, Jingjing Li, Xinqi Wu
The combination of anti-VEGF blockade (bevacizumab) with immune checkpoint anti–CTLA-4 blockade (ipilimumab) in a phase I study showed tumor endothelial activation and immune cell infiltration that were associated with favorable clinical outcomes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b80d0f948aca633b7e27827821e1831c
https://doi.org/10.1158/2326-6066.c.6548621.v1
https://doi.org/10.1158/2326-6066.c.6548621.v1
Autor:
F. Stephen Hodi, Margaret Shipp, Scott Rodig, Glenn Dranoff, Matthias Piesche, Jun Zhou, George Murphy, David McDermott, Donald Lawrence, Anita Giobbie-Hurder, Jing Ouyang, Xiaoyun Liao, Erin M. Connolly, Jingjing Li, Xinqi Wu
Supplementary Table S1. Clinical responses and survival of patients with durable clinical benefit. Supplementary Table S2. Time between pre-treatment and post-treatment samples and the fold changes for Gal-1 antibodies. Supplementary Table S3. Distri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63e24af70c3be3d7748bb783273b29e0
https://doi.org/10.1158/2326-6066.22537952.v1
https://doi.org/10.1158/2326-6066.22537952.v1
Autor:
Tobias Schatton, Christian Posch, Steven Barthel, Matthew Ramsey, George Murphy, Nuh Rahbari, Manisha Thakuria, Anne Brandenburg, Kyla Mucciarone, Sonja Kleffel, Erik Rasbach, Christina Martins, Markus Heppt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06f1d412bb903a88df60a77849442267
https://doi.org/10.26226/m.62fa00a04b6034001b1c3178
https://doi.org/10.26226/m.62fa00a04b6034001b1c3178