Zobrazeno 1 - 10
of 73
pro vyhledávání: '"George Mosialos"'
Autor:
Vagelis Rinotas, Kalliopi Iliaki, Lydia Pavlidi, Theodore Meletakos, George Mosialos, Marietta Armaka
Publikováno v:
Cell Death and Disease, Vol 15, Iss 8, Pp 1-9 (2024)
Abstract TNF is a potent cytokine known for its involvement in physiology and pathology. In Rheumatoid Arthritis (RA), persistent TNF signals cause aberrant activation of synovial fibroblasts (SFs), the resident cells crucially involved in the inflam
Externí odkaz:
https://doaj.org/article/679df6fcc9864c43b88db173b36958d6
Autor:
Athanasios Pseftogkas, Jessica Bordini, Michela Frenquelli, Ferdinando Bonfiglio, Masanori Daibata, José Ángel Martínez-Climent, George Mosialos, Davide Rossi, Alessandro Campanella, Konstantinos Xanthopoulos, Paolo Ghia
Publikováno v:
HemaSphere, Vol 7, p e1177106 (2023)
Externí odkaz:
https://doaj.org/article/61f1b3190d4444e1947671f7a5c453be
Publikováno v:
Journal of Biological Research - Thessaloniki, Vol 29, Iss 0 (2021)
Deregulated lipid metabolism has been recognized as a critical alteration that supports the development and growth of various types of tumors. Changes in lipid metabolism enable reprogramming of energetics and availability of synthetic intermediates
Externí odkaz:
https://doaj.org/article/88b655a002f9466fa63b0218e70d722b
Autor:
Paul Hadweh, Iro Chaitoglou, Maria Joao Gravato-Nobre, Petros Ligoxygakis, George Mosialos, Eudoxia Hatzivassiliou
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191864 (2018)
The human cylindromatosis tumor suppressor (HsCyld) has attracted extensive attention due to its association with the development of multiple types of cancer. HsCyld encodes a deubiquitinating enzyme (HsCYLD) with a broad range of functions that incl
Externí odkaz:
https://doaj.org/article/4ff9bfc03ef343d5b8b468904f798cf6
Autor:
Eirini Trompouki, Ageliki Tsagaratou, Stylianos K. Kosmidis, Pascal Dollé, Jun Qian, Dimitris L. Kontoyiannis, Wellington V. Cardoso, George Mosialos
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 5, Pp 469-476 (2009)
Cyld encodes a 956-amino acid deubiquitinating enzyme (CYLD), which is a negative regulator of nuclear factor κB and mitogen-activated protein kinase pathways. Mutations that truncate and inactivate the carboxyl-terminal deubiquitinating domain of C
Externí odkaz:
https://doaj.org/article/4b22d7ca9a8743fdbf02ddf1dfb39f86
Autor:
Vassilis Mavromatidis, Zoltan Varga, Frigyes Waczek, Zoltán Őrfi, László Őrfi, György Kéri, George Mosialos
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95688 (2014)
Epstein-Barr virus (EBV) is a human herpesvirus, which is causally associated with the development of several B lymphocytic malignancies that include Burkitt's lymphomas, Hodgkin's disease, AIDS and posttransplant associated lymphomas. The transformi
Externí odkaz:
https://doaj.org/article/e12914d92de047f4873a5f54d353315e
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16397 (2011)
The cylindromatosis tumor suppressor (CYLD) is a deubiquitinating enzyme that has been implicated in various aspects of adaptive and innate immune responses. Nevertheless, the role of CYLD in the function of specific types of immune cells remains elu
Externí odkaz:
https://doaj.org/article/b4a519c13def47c49c369590e976cad1
Autor:
Dimitrios Giakoustidis, Athanasios Apostolos Gargavanis, Kali Makedou, Thomas Goulopoulos, Alexander Giakoustidis, George Mosialos, Hara Afaloniati, Theofilos Poutahidis, Alexandros Hardas, Stavros Iliadis, Katerina Angelopoulou, Athanasios Pseftogas, Vasileios Papadopoulos, Apostolos Papalois
Publikováno v:
OncoTargets and Therapy. 13:5575-5588
Background Hepatocellular carcinoma (HCC) is a frequently diagnosed cancer and a leading cause of cancer-related death worldwide. Its rapid progression, combined with the limited treatment options at late stages, imposes the need for early detection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff81ae0fdb84cd5884c556ca8016e596
https://doi.org/10.2147/ott.s250233
https://doi.org/10.2147/ott.s250233
Autor:
Christos Gonidas, Eudoxia Hatzivassiliou, Alexander Hardas, Theofilos Poutahidis, Chrysanthi Ainali, Xaralabos Varelas, Joseph G. Kern, Athanasios Pseftogas, Dimitra Dafou, Anastasia Tsingotjidou, Konstantinos Xanthopoulos, Emmanuel Panteris, George Mosialos
Publikováno v:
Cancers
Cancers, Vol 12, Iss 2047, p 2047 (2020)
Volume 12
Issue 8
Cancers, Vol 12, Iss 2047, p 2047 (2020)
Volume 12
Issue 8
Downregulation of the cylindromatosis (CYLD) tumor suppressor has been associated with breast cancer development and progression. Here, we report a critical role for CYLD in maintaining the phenotype of mammary epithelial cells in vitro and in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9d359a6bc9a2de4dba2ecbbc53b335a
http://europepmc.org/articles/PMC7466024
http://europepmc.org/articles/PMC7466024
Autor:
Paul Brennan, Laia Alemany, Devasena Anantharaman, Rengaswamy Sankaranarayanan, Rekha V. Kumar, Marisa Mena, Heiner Boeing, Massimo Tommasino, Fausto Chiesa, Susanna Chiocca, Marc Arbyn, Ranjit V. Thorat, Kortikere S. Sabitha, Olivier M. Vanderveken, Bhagwan M. Nene, Subha Sankaran, Johannes Bogers, Christine Carreira, Peter Vermeulen, R. S. Jayshree, Gerhard Dyckhoff, George Mosialos, Sandrine McKay-Chopin, Dana Holzinger, Amal C Kataki, Alfredo Zito, Fausto Maffini, Susanne Rehm, Tarik Gheit, Ivana Gorbaslieva, Mohssen Ansarin, Madhavan Radhakrishna Pillai, Eric Lucas, Alessandro Caniglia, Xavier Castellsagué, Francesc Bosch, Aruna S. Chiwate, Maria Belén Lloveras Rubio, Marta Tagliabue, Ruediger Ridder, Shashikant S. Lakshetti, Girish G. Hublikar, Cindy Simoens, Michael Pawlita, Martin Lammens, Nitin Gangane, Ashok Kumar Das, Thara Somanathan, Kunnambath Ramadas, Pulikottil Okkuru Esmy, Christel Herold-Mende, Ashok M. Shenoy, Silvia de Sanjosé, M. Vijayakumar
Publikováno v:
Cancer epidemiology
Background: The main risk factors for head and neck cancer (HNC) are tobacco and alcohol use. However, an important fraction of oropharyngeal cancer (OPC) is caused by human papillomaviruses (HPV), a subgroup with increasing incidence in several west
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ab4b16294fcbb9f1a558943669182e
https://doi.org/10.1016/j.canep.2021.101925
https://doi.org/10.1016/j.canep.2021.101925