Zobrazeno 1 - 10
of 142
pro vyhledávání: '"George Morgan"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Sickle cell disease (SCD) is an inherited, progressively debilitating blood disorder. Emerging gene therapies (GTx) may lead to a complete remission, the benefits of such can only be realized if GTx is affordable and accessible in the low-an
Externí odkaz:
https://doaj.org/article/848c30df487d43bebf0989dd9c31e0d1
Autor:
Jessica Caffry, Matthew Selby, Katie Barr, George Morgan, David McGurk, Philip Scully, Catherine Park, Anna-Maria Caridis, Emily Southworth, Jack Morrison, David J. Clark, Benedict M. O. Davies, Nicholas M. Eckersley, Elisabetta Groppelli, Daniela E. Kirwan, Irene Monahan, Yolanda Augustin, Colin Toombs, Tim Planche, Henry M. Staines, Sanjeev Krishna
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Accurate and rapid point-of-care (PoC) diagnostics are critical to the control of the COVID-19 pandemic. The current standard for accurate diagnosis of SARS-CoV-2 is laboratory-based reverse transcription polymerase chain reaction (RT-PCR) a
Externí odkaz:
https://doaj.org/article/992de527d1334150a0854e0e19ba2c83
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-8 (2023)
Abstract Background Haemophilia A is a bleeding disorder caused by deficiency of coagulation factor VIII (FVIII) which leads to severe and repeated bleedings. There is a need to understand the optimal treatment pathway for FVIII inhibitors with the u
Externí odkaz:
https://doaj.org/article/b852cc8a385c44a29c31e8f118c5f26f
Autor:
Tamanna Rahman, Saman Tavana, Nicoleta Baxan, Kay A. Raftery, George Morgan, Thomas P. Schaer, Nigel Smith, Axel Moore, Jonathan Bull, Molly M. Stevens, Nicolas Newell
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction: Nucleus replacement has been proposed as a treatment to restore biomechanics and relieve pain in degenerate intervertebral discs (IVDs). Multiple nucleus replacement devices (NRDs) have been developed, however, none are currently used r
Externí odkaz:
https://doaj.org/article/6c25727228fb41948c0b60ffc96f6780
Autor:
Nabila Ismail, Anzaan Dippenaar, George Morgan, Melanie Grobbelaar, Felicia Wells, Jessica Caffry, Cristiana Morais, Krzysztof Gizynski, David McGurk, Eduardo Boada, Heather Murton, Robin M. Warren, Annelies Van Rie
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Mycobacterium tuberculosis whole-genome sequencing (WGS) is a powerful tool as it can provide data on population diversity, drug resistance, disease transmission, and mixed infections. Successful WGS is still reliant on high concentrations o
Externí odkaz:
https://doaj.org/article/98ab556599db40239b79132b4ae9e34a
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 28 (2022)
Recent international guidelines conditionally recommend von Willebrand factor (VWF) prophylaxis for von Willebrand disease (VWD) patients with a history of severe/frequent bleeds. This post hoc analysis of the Cost of VWD Across Europe, a Socioeconom
Externí odkaz:
https://doaj.org/article/12bdff84e0584a09ac8c85f91bc84469
Autor:
George Morgan MSc, Sarah Brighton BSc, Mike Laffan BA, BMBCh, DM, FRCP, FRCPath, Jenny Goudemand MD, Bethany Franks MSc, Alan Finnegan PhD, RN, FRCN, FRSA, CF, FAAN
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 28 (2022)
Background Von Willebrand disease (VWD) is one of the most common inherited bleeding disorders, imposing a substantial health impact and financial burden. The C ost of v on Willebrand disease in E urope: A S ocioeconomic S tudy (CVESS) characterises
Externí odkaz:
https://doaj.org/article/a626d4992a2c4102859a73fdd5932ed0
Publikováno v:
Advanced Materials Interfaces, Vol 8, Iss 24, Pp n/a-n/a (2021)
Abstract Understanding novel actuating materials which respond to a variety of stimuli is key in the development of micro/nanoscale robotics. In this work, the mechanism of actuation in nickel hydroxide/oxyhydroxide actuators by the intercalation/dei
Externí odkaz:
https://doaj.org/article/b3cc3605653b4d61aa6960e246563c98
Publikováno v:
BMJ Open, Vol 11, Iss 5 (2021)
Objectives The benefits of minimally invasive surgery (MIS) for endometrial carcinoma (EC) are well established although the financial impact of robotic-assisted hysterectomy (RH) compared with laparoscopic hysterectomy (LH) is disputed.Design Retros
Externí odkaz:
https://doaj.org/article/0737f42ae3dc41c7af7a177e93f390c3
Autor:
Jamie O'Hara, Alan Finnegan, Harpal Dhillon, Leonardo Ruiz-Casas, Gabriel Pedra, Bethany Franks, George Morgan, Vanessa Hebditch, Bengt Jönsson, Mzwandile Mabhala, Tatjana Reic, Ingo Van Thiel, Vlad Ratziu, Manuel Romero-Gomez, Elisabetta Bugianesi, Jörn M. Schattenberg, Quentin M. Anstee
Publikováno v:
JHEP Reports, Vol 2, Iss 5, Pp 100142- (2020)
Background & Aims: Non-alcoholic steatohepatitis (NASH) leads to cirrhosis and is associated with a substantial socioeconomic burden, which, coupled with rising prevalence, is a growing public health challenge. However, there are few real-world data
Externí odkaz:
https://doaj.org/article/442840db6e7b4fcfafbe49ed134527fb