Zobrazeno 1 - 10
of 97
pro vyhledávání: '"George Minadakis"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 378-387 (2023)
PathIN is a web-service that provides an easy and flexible way for rapidly creating pathway-based networks at several functional biological levels: genes, compounds and reactions. The tool is supported by a database repository of reference pathway ne
Externí odkaz:
https://doaj.org/article/e7a63368209d4d928d4d4e1d0e8d0026
Autor:
George Minadakis, Alfonso Muñoz-Pomer Fuentes, George Tsouloupas, Irene Papatheodorou, George M. Spyrou
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 4336-4344 (2021)
A fundamental issue related to the understanding of the molecular mechanisms, is the way in which common pathways act across different biological experiments related to complex diseases. Using network-based approaches, this work aims to provide a num
Externí odkaz:
https://doaj.org/article/c656260f08c4429c961d44df02687693
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 1695-1703 (2020)
ProTExA is a web-tool that provides a post-processing workflow for the analysis of protein and gene expression datasets. Using network-based bioinformatics approaches, ProTExA facilitates differential expression analysis and co-expression network ana
Externí odkaz:
https://doaj.org/article/90b1299aaef0478b8c9270e25b79b301
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 939-945 (2019)
Drug repurposing techniques allow existing drugs to be tested against diseases outside their initial spectrum, resulting in reduced cost and eliminating the long time-frames of new drug development. In silico drug repurposing further speeds up the pr
Externí odkaz:
https://doaj.org/article/65ab3e371caa44cab472b8584f24c82c
Autor:
Anastasis Oulas, Maria Zanti, Marios Tomazou, Margarita Zachariou, George Minadakis, Marilena M Bourdakou, Pavlos Pavlidis, George M Spyrou
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0238665 (2021)
This study aims to highlight SARS-COV-2 mutations which are associated with increased or decreased viral virulence. We utilize genetic data from all strains available from GISAID and countries' regional information, such as deaths and cases per milli
Externí odkaz:
https://doaj.org/article/a6c2749562614ee591ac95a61aaabdf4
Autor:
Kosmas Tsakiridis, Konstantina Triantafilopoulou, George Minadakis, Apostolos Zatagias, Konstantinos Sapalidis, Christoforos Kosmidis, Aris Ioannidis, Konstantinos Romanidis, Panagoula Oikonomou, Christina Sevva, Nikolaos Michalopoulos, Iason Nikolaos Katsios, Alexandru Marian Goganau, Michael Platanas, Anastasios Vagionas, Paul Zarogoulidis
Publikováno v:
Respiratory Medicine Case Reports, Vol 30, Iss , Pp 101036- (2020)
Catamenial pneumothorax (CP) is considered to be the most common form of thoracic endometriosis syndrome, which also includes catamenial hemothorax, catamenial hemopneumothorax, catamenial hemoptysis, and endometriosis lung nodules. Diagnosis can be
Externí odkaz:
https://doaj.org/article/230ebafe8fbf4d73a0a994dbe7b39d29
Publikováno v:
Briefings in Bioinformatics. 24
We draw from the assumption that similarities between pathogens at both pathogen protein and host protein level, may provide the appropriate framework to identify and rank candidate drugs to be used against a specific pathogen. Vir2Drug is a drug rep
Autor:
Gerassimos A. Papadopoulos, Apostolos Agalos, George Minadakis, Ioanna Triantafyllou, Pavlos Krassakis
Publikováno v:
Sensors, Vol 20, Iss 19, p 5681 (2020)
Significant seismicity anomalies preceded the 25 October 2018 mainshock (Mw = 6.8), NW Hellenic Arc: a transient intermediate-term (~2 yrs) swarm and a short-term (last 6 months) cluster with typical time-size-space foreshock patterns: activity incre
Externí odkaz:
https://doaj.org/article/3499e3f880194db4ab137c355d623849
Autor:
Andrea C. Kakouri, Christina Votsi, Marios Tomazou, George Minadakis, Evangelos Karatzas, Kyproula Christodoulou, George M. Spyrou
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6722 (2020)
Spastic ataxia (SA) is a group of rare neurodegenerative diseases, characterized by mixed features of generalized ataxia and spasticity. The pathogenetic mechanisms that drive the development of the majority of these diseases remain unclear, although
Externí odkaz:
https://doaj.org/article/fc17ad7828f842e0a695b6b42a838248
Autor:
Anastasis Oulas, George Minadakis, Margarita Zachariou, Marios Tomazou, Alexios Vlamis-Gardikas, George M Spyrou
Publikováno v:
NAR Genomics and Bioinformatics. 5
Bacterial Wars (BW) is a network-based tool that applies a two-step pipeline to display information on the competition of bacterial species found in the same microbiome. It utilizes antimicrobial peptide (AMP) sequence similarities to obtain a relati