Zobrazeno 1 - 10
of 37
pro vyhledávání: '"George M. Lawson"'
Autor:
Ivana T. Croghan, Richard D. Hurt, Lowell C. Dale, George M. Lawson, Allena J. Ji, Rodger W Anderson
Publikováno v:
Clinical Chemistry. 45:85-91
trans-3′-Hydroxycotinine (THOC) has been recognized as the most abundant metabolite of nicotine. In an attempt to assess THOC and cotinine (COT) concentrations during nicotine transdermal therapy, we developed a new quantitative gas chromatography
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ecc69e6add8954c3e5a66c8a9b11a50
https://doi.org/10.1093/clinchem/45.1.85
https://doi.org/10.1093/clinchem/45.1.85
Autor:
Darrell R. Schroeder, Ivana T. Croghan, Lowell C. Dale, George M. Lawson, Kenneth P. Offord, Nai S. Jiang, Richard D. Hurt
Publikováno v:
The Journal of Clinical Pharmacology. 38:502-509
As part of a clinical trial investigating the level of nicotine replacement with different doses of transdermal therapy for smoking cessation, peak and trough serum nicotine and plasma cotinine concentrations were measured in 70 subjects while they w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89641fa9babbeb9b28cf8f5c0451905b
https://doi.org/10.1002/j.1552-4604.1998.tb05787.x
https://doi.org/10.1002/j.1552-4604.1998.tb05787.x
Autor:
George M. Lawson, Victor G. Dávila-Román, Jane M. Helgeson, Michael Landt, Jack H. Ladenson, Robert C. Hickner, Allan S. Jaffe
Publikováno v:
Metabolism. 46:1109-1112
Serum leptin and free fatty acid concentrations were determined in two groups of subjects undergoing strenuous exercise: 12 men who fasted overnight and then pedaled a stationary ergometer for 2 hours, and 14 nonfasting ultramarathon runners. Blood s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6adf1b5ba740a61a5131d86bde67ac5a
https://doi.org/10.1016/s0026-0495(97)90200-6
https://doi.org/10.1016/s0026-0495(97)90200-6
Autor:
William J. Tremaine, Kenneth P. Batts, J Green, Kenneth P. Offord, James J. Lipsky, Jonathan A. Leighton, William J. Sandborn, Bradley J. Zins, Dennis C. Mays, Richard D. Hurt, George M. Lawson, R. F. Compton
Publikováno v:
Alimentary Pharmacology and Therapeutics. 11:663-671
Background: Ulcerative colitis is predominantly a disease of non-smokers, and transdermal nicotine is therapeutic but often results in side-effects. Administration of nicotine as a liquid rectal enema results in less systemic nicotine absorption. Aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2008e58b5d56a10e7af20414697aaf38
https://doi.org/10.1046/j.1365-2036.1997.00208.x
https://doi.org/10.1046/j.1365-2036.1997.00208.x
Autor:
Alan R. Zinsmeister, Dennis C. Mays, James J. Lipsky, William J. Sandborn, Jeffrey A. McKinney, George M. Lawson, Kenneth P. Offord, Richard D. Hurt, Douglas W. Mahoney, Bradley J. Zins, William J. Tremaine
Publikováno v:
The Journal of Clinical Pharmacology. 37:426-436
Ulcerative colitis is predominantly a disease of nonsmokers, and transdermal nicotine is therapeutic but often results in adverse reactions. Colonic administration of nicotine tartrate as a liquid enema could decrease systemic nicotine absorption and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d8841a66036dcc80aa875079238dd8
https://doi.org/10.1002/j.1552-4604.1997.tb04320.x
https://doi.org/10.1002/j.1552-4604.1997.tb04320.x
Publikováno v:
Analytical Chemistry. 69:99-104
A significant fraction of the total analysis time (injection-to-injection) in capillary electrophoresis is dedicated to a rigorous between-run capillary rinsing/regeneration procedure. This is of particular importance with CE-based assays developed f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b399de1641c742e4ddbde03788b9704e
https://doi.org/10.1021/ac960514+
https://doi.org/10.1021/ac960514+
Publikováno v:
Electrophoresis. 18:1865-1874
Micellar electrokinetic chromatography (MEKC) in tandem with diode array detection (DAD) has been exploited as an analytical method for the separation and detection of sulfonylurea drugs. The ultimate goal is the development of an assay to detect the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cff93bf4b5418173f8b3e3fe238e30
https://doi.org/10.1002/elps.1150181024
https://doi.org/10.1002/elps.1150181024
Autor:
Russell H. Wiesner, Michael K. Porayko, Gregory J. Gores, Ruud A.F. Krom, Timothy J. Cody, J. Eileen Hay, William J. Sandborn, George M. Lawson, Jeffery L. Steers
Publikováno v:
Hepatology. 21:70-76
We have previously reported that low hepatic tissue cyclosporine levels correlate with early cellular rejection after liver transplantation. The aim of this study is to determine whether there is a similar relationship in patients treated with FK506.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4ac728ba69ec32ce41da8729629af2d
https://doi.org/10.1016/0270-9139(95)90410-7
https://doi.org/10.1016/0270-9139(95)90410-7
Autor:
Russell H. Wiesner, Ruud A.F. Krom, Gregory J. Gores, Timothy J. Cody, Michael K. Porayko, George M. Lawson, J. Eileen Hay, Jeffery L. Steers, William J. Sandborn
Publikováno v:
Hepatology. 21:70-76
We have previously reported that low hepatic tissue cyclosporine levels correlate with early cellular rejection after liver transplantation. The aim of this study is to determine whether there is a similar relationship in patients treated with FK506.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e5f6143b16ad807cf8da42afc6a34ed
https://doi.org/10.1002/hep.1840210113
https://doi.org/10.1002/hep.1840210113
Publikováno v:
Clinical Chemistry. 40:1312-1316
This automated assay determines the concentration of the antidepressant fluoxetine (Prozac) and its active metabolite norfluoxetine in serum by reversed-phase HPLC with spectrophotometric detection. Extraction, injection, and quantification are perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d8068dda839045548cf95df000a8ef0
https://doi.org/10.1093/clinchem/40.7.1312
https://doi.org/10.1093/clinchem/40.7.1312