Zobrazeno 1 - 10
of 40
pro vyhledávání: '"George M. Hilliard"'
Autor:
George M. Hilliard, Joachim Morschhäuser, Phillip Rogers, Christopher F. Hoehamer, Edwin D. Cummings
Publikováno v:
PROTEOMICS. 9:4726-4730
The gain-of-function mutation G648D in UPC2 causes ERG11 up-regulation and increased fluconazole resistance in Candida albicans. In this study, we performed 2-DE and PMF to identify proteomic alterations in an ERG11-overexpressing fluconazole-resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7adb5816a8dc3a822ead20d245f65ec
https://doi.org/10.1002/pmic.200900176
https://doi.org/10.1002/pmic.200900176
Autor:
George M. Hilliard, P. David Rogers, Joachim Morschhäuser, Edwin D. Cummings, Christopher F. Hoehamer
Publikováno v:
PROTEOMICS - CLINICAL APPLICATIONS. 3:968-978
Azole resistance in Candida albicans is frequently caused by the overexpression of multi-drug efflux pump genes MDR1, CDR1, and CDR2 due to gain-of-function mutations in the zinc cluster transcription factors Mrr1p and Tac1p. In this study, we perfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b06bd37ab58732f2e11777cc5b0e176
https://doi.org/10.1002/prca.200800252
https://doi.org/10.1002/prca.200800252
Autor:
Martin Tenniswood, Steven A. Carr, Karen A. West, J Lakins, John W. Crabb, James T. Kapron, George M. Hilliard
Publikováno v:
Protein Science. 6:2120-2133
Clusterin is a ubiquitous, heterodimeric glycoprotein with multiple possible functions that are likely influenced by glycosylation. Identification of oligosaccharide attachment sites and structural characterization of oligosaccharides in human serum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90e3236fd0745167da7745e124a22c1
https://doi.org/10.1002/pro.5560061007
https://doi.org/10.1002/pro.5560061007
Autor:
Koushik Roy, Marguerite M. Ostmann, James M. Fleckenstein, Jiwen Luo, George M. Hilliard, David J. Hamilton
Publikováno v:
Nature
Adhesion to epithelial cells1 and flagella-mediated motility are critical virulence traits for many Gram-negative pathogens, including enterotoxigenic Escherichia coli (ETEC)2, a major cause of diarrhoea in travellers and children in developing count
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08845fdbeae8f3d529f7822792e850e7
https://doi.org/10.1038/nature07568
https://doi.org/10.1038/nature07568
Autor:
Katherine S. Barker, George M. Hilliard, Justin Thornton, Teresa T. Liu, Larry S. McDaniel, P. David Rogers, Edwin Swiatlo, B. Keith English
Publikováno v:
Journal of Antimicrobial Chemotherapy. 59:616-626
Objectives: The aim of this study was to identify changes in the gene expression profile of Streptococcus pneumoniae in response to a subinhibitory concentration of penicillin in an effort to better understand mechanisms by which this organism copes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5d1d400bbc4e919cc37074013350a6
https://doi.org/10.1093/jac/dkl560
https://doi.org/10.1093/jac/dkl560
Publikováno v:
Journal of Antimicrobial Chemotherapy. 58:434-438
Objectives: The aim of the present study was to identify changes in the proteome of a laboratory-derived azole-resistant strain of Candida glabrata compared with its susceptible parent strain in an effort to identify proteins that are differentially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd6e2ea2fff568b15a65df92e21a300
https://doi.org/10.1093/jac/dkl221
https://doi.org/10.1093/jac/dkl221
Publikováno v:
The Journal of Immunology. 176:68-74
Deficiencies in clearance of apoptotic cells predispose to the development of autoimmune disease. This is evident in mice lacking the receptor tyrosine kinases Tyro3, Axl, and Mer. Deficient mice exhibit an increased abundance of apoptotic cells in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0edd6d86df5354ce05f337d12928868
https://doi.org/10.4049/jimmunol.176.1.68
https://doi.org/10.4049/jimmunol.176.1.68
Publikováno v:
Biochemistry. 44:2759-2769
Apolipoprotein (apo) A-I, a 243-residue, 28.1-kDa protein is a major mediator of the reverse cholesterol transport (RCT) pathway, a process that may reduce the risk of cardiovascular disease in humans. In plasma, a small fraction of lipid-free or lip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43f9c4f80e91ca069813bc874bad53da
https://doi.org/10.1021/bi047717+
https://doi.org/10.1021/bi047717+
Publikováno v:
Journal of Applied Physiology. 96:802-808
We have shown that the specific inhibition of hypoxia-induced relaxation by organ culture in porcine coronary arteries can be mimicked by treatment of control vessels with the protein synthesis inhibitor, cycloheximide. We hypothesize that organ cult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4910cb249f1b3d966ff09b687bf38385
https://doi.org/10.1152/japplphysiol.00817.2003
https://doi.org/10.1152/japplphysiol.00817.2003
Autor:
W. Sean Davidson, George M. Hilliard
Publikováno v:
Journal of Biological Chemistry. 278:27199-27207
The three-dimensional structure of human apoA-I on nascent, discoidal HDL particles has been debated extensively over the past 25 years. Recent evidence has demonstrated that the α-helical domains of apoA-I are arranged in a belt-like orientation wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3dad2847a23c403c6c180b1ea281811
https://doi.org/10.1074/jbc.m302764200
https://doi.org/10.1074/jbc.m302764200