Zobrazeno 1 - 4
of 4
pro vyhledávání: '"George M. Dytko"'
Autor:
Vawter L, Derk J. Bergsma, Xiang Li, Shelagh Wilson, Robert S. Ames, Tierney La, Alston J, Boyce R, Hsiao-Ling Wu, Zhu Y, Henry M. Sarau, Fitzgerald Lr, George M. Dytko, Mannan Ij, J.P. Hieble, Nicole C. Herrity, Davenport Cm, Michalovich D, Tan Kb
Publikováno v:
Molecular Pharmacology. 59:434-441
Using a genomics-based reverse pharmacological approach for screening orphan G-protein coupled receptors, we have identified and cloned a novel high-affinity histamine receptor. This receptor, termed AXOR35, is most closely related to the H3 histamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8275e15c20f6649c1e6e629a7aa2a9
https://doi.org/10.1124/mol.59.3.434
https://doi.org/10.1124/mol.59.3.434
Autor:
Jon K. Chambers, Laura R. Fitzgerald, Shelagh Wilson, Philip G. Szekeres, Nabil Elshourbagy, Usman Shabon, Dulcie B. Schmidt, George M. Dytko, Nicholas A. Evans, Derk J. Bergsma, Robert S. Ames, Kong B. Tan, Henry M. Sarau, Da Yuan Wang, Graeme Milligan, D. Alex Groarke, Peter T. Buckley, Paul R. Murdock, James J. Foley, Parvathi Nuthulaganti
Publikováno v:
Journal of Biological Chemistry. 275:25965-25971
Opiate tolerance and dependence are major clinical and social problems. The anti-opiate neuropeptides FF and AF (NPFF and NPAF) have been implicated in pain modulation as well as in opioid tolerance and may play a critical role in this process, altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5cafd790b16038f625a65339c455f1
https://doi.org/10.1074/jbc.m004515200
https://doi.org/10.1074/jbc.m004515200
Autor:
Peter T. Buckley, Paul R. Murdock, Catherine E. Ellis, Nabil Elshourbagy, Owen Jenkins, Douglas W. P. Hay, Nicole C. Herrity, Ganesh M. Sathe, James J. Foley, Alison I. Muir, Parvathi Nuthulaganti, Jon K. Chambers, Shelagh Wilson, Roseanna M. Muccitelli, George M. Dytko, Wendy S. Halsey, Dulcie B. Schmidt, Henry M. Sarau, Derk J. Bergsma, Robert S. Ames
Publikováno v:
Molecular Pharmacology. 56:657-663
The cysteinyl leukotrienes (CysLTs) have been implicated in the pathophysiology of inflammatory disorders, in particular asthma, for which the CysLT receptor antagonists pranlukast, zafirlukast, and montelukast, have been introduced recently as novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b162a4b722162fccd8a0083f840edb
https://doi.org/10.1124/mol.56.3.657
https://doi.org/10.1124/mol.56.3.657
Publikováno v:
Analytical biochemistry. 275(1)
We have established a rapid, sensitive, high-throughput assay that requires one assay condition to detect agonist effects from Gi-, Gs-, and Gq-coupled receptors. We utilized a vector containing a promoter with three multiple response elements, the v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26002027c7d3e6ad206ad935c549c3e
https://pubmed.ncbi.nlm.nih.gov/10542109
https://pubmed.ncbi.nlm.nih.gov/10542109