Zobrazeno 1 - 6
of 6
pro vyhledávání: '"George M. Chan"'
Autor:
Dirk A. Heerding, Walter E. DeWolf, Stephen Rittenhouse, William H. Miller, Kalindi Vaidya, Catherine C.K. Yuan, Xiayang Qiu, Dennis T. Takata, Courtney Slater-Radosti, Cheryl A. Janson, Ward W. Smith, Andrew P. Fosberry, Terrance D. Moore, Edward McManus, William F. Huffman, Deborah Dee Jaworski, David J. Payne, George M. Chan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:2061-2065
1,4-Disubstituted imidazole inhibitors of Staphylococcus aureus and Escherichia coli enoyl acyl carrier protein reductase (FabI) have been identified. Crystal structure data shows the inhibitor 1 bound in the enzyme active site of E. coli FabI.
Autor:
Stephen J Kirchner, Pradip Mukerji, Jennifer Thurmond, Yung-Sheng Huang, Emil G. Bobik, Knutzon Deborah, Chaudhary Sunita, George M. Chan, Ling Yuan
Publikováno v:
Lipids. 34:649-659
Two cDNA clones with homology to known desaturase genes were isolated from the fungus Mortierella alpina. The open reading frame in one clone encoded 399 amino acids and exhibited delta12-desaturase activity when expressed in Saccharomyces cerevisiae
Autor:
D. John Faulkner, Glenn A. Hofmann, Reinaldo S. Compagnone, Michael R. Mattern, Mark E. Hemling, Brad Carte, Alan J. Freyer, George M. Chan
Publikováno v:
Tetrahedron. 50:12785-12792
The ascidian Lissoclinum japonicum from Palau contained the antimicrobial and antifungal metabolites N,N-dimethyl-5-(methylthio)varacin ( 6 ) and 3,4-dimethoxy-6-(2'−N,N-dimethylaminoethyl)-5-(methylthio)benzotrithiane ( 7 ), both of which were iso
Autor:
Victor K. Johnston, Carol Silverman, Ricardo Macarron, Arun C. Kaura, George M. Chan, Kevin J. Duffy, Alfred DelVecchio, Adam T. Gates, Hung-Yuan Cheng, Sanjay S. Khandekar, Derrick Maley, Baohua Gu, Lester L. Gutshall, Zaid Alnoah, Dashyant Dhanak, Antony N. Shaw, Robert T. Sarisky, Glenn A. Hofmann, Cathy Greenwood, David J. Casper, Richard M. Keenan, David L. Earnshaw, Michael R. Nonnemacher, Michael G. Darcy, Juili Lin-Goerke, Audrey Baker
Publikováno v:
The Journal of biological chemistry. 277(41)
The hepatitis C virus (HCV) NS5B protein encodes an RNA-dependent RNA polymerase (RdRp), the primary catalytic enzyme of the HCV replicase complex. We established a biochemical RNA synthesis assay, using purified recombinant NS5B lacking the C-termin
Autor:
George M. Chan, Huang Yung-Sheng, Pradip Mukerji, Jennifer Thurmond, Sunita Chaudhary, Knutzon Deborah
Publikováno v:
Plant Biotechnology and In Vitro Biology in the 21st Century ISBN: 9789401059664
Polyunsaturated fatty acids (PUFAs) are important components of infant as well as adult nutrition due to their roles as both structural elements of cell membranes and as precursors to eicosanoids, a family of potent biological effectors such as prost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::092171bd6bea1bb3f010d8326c1fe6be
https://doi.org/10.1007/978-94-011-4661-6_130
https://doi.org/10.1007/978-94-011-4661-6_130
Autor:
Stephen J Kirchner, Chaudhary Sunita, Emil G. Bobik, Knutzon Deborah, George M. Chan, Pradip Mukerji, Jennifer Thurmond, Yung-Sheng Huang
Publikováno v:
The Journal of biological chemistry. 273(45)
A DNA fragment with homology to Delta6-desaturases from borage and cyanobacteria was isolated after polymerase chain reaction amplification of Mortierella alpina cDNA with oligonucleotide primers corresponding to the conserved regions of known Delta6