Zobrazeno 1 - 10
of 75
pro vyhledávání: '"George Lykotrafitis"'
Publikováno v:
JOR Spine, Vol 3, Iss 3, Pp n/a-n/a (2020)
Abstract Degeneration of the intervertebral disc (IVD) is a condition that is often associated with debilitating back pain. There are no disease‐modifying treatments available to halt the progression of this ubiquitous disorder. This is partly due
Externí odkaz:
https://doaj.org/article/aaaea219b5ef468c9cecc0a51c1a9b56
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 5, p e1007003 (2019)
The axon plasma membrane consists of the membrane skeleton, which comprises ring-like actin filaments connected to each other by spectrin tetramers, and the lipid bilayer, which is tethered to the skeleton via, at least, ankyrin. Currently it is unkn
Externí odkaz:
https://doaj.org/article/51dbc9105d174deaba968c6a55c7f829
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216467 (2019)
Abnormal red blood cell (RBC) adhesion to endothelial αvβ3 plays a crucial role in triggering vaso-occlusive episodes in sickle cell disease (SCD). It is known that epinephrine, a β-adrenergic receptor (β-AR) stimulator, increases the RBC surface
Externí odkaz:
https://doaj.org/article/e0799f87fe4d4361bca0dfaa277968b0
Autor:
Yihao Zhang, Krithika Abiraman, He Li, David M Pierce, Anastasios V Tzingounis, George Lykotrafitis
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 2, p e1005407 (2017)
Super-resolution microscopy recently revealed that, unlike the soma and dendrites, the axon membrane skeleton is structured as a series of actin rings connected by spectrin filaments that are held under tension. Currently, the structure-function rela
Externí odkaz:
https://doaj.org/article/1d5fef9c5fce4e20905a90d9ccac848a
Publikováno v:
Soft Matter. 19:2514-2528
A coarse-grain model of the periodic axon plasma membrane skeleton illustrates that spectrin unfolding protects the axon during low-rate extensions but actin-spectrin dissociations dominates high-rate extensions finally causing rupture of the axon.
Publikováno v:
Biophysical Journal. 121:3334-3344
Recent work has established that axons have a periodic skeleton structure comprising of azimuthal actin rings connected via longitudinal spectrin tetramer filaments. This structure endows the axon with structural integrity and mechanical stability. A
Publikováno v:
Function. 4
Small-conductance calcium-activated potassium (SK) channels show a ubiquitous distribution on neurons, in both somatodendritic and axonal regions. SK channels are associated with neuronal activity regulating action potential frequency, dendritic exci
Recent work has established that axons have a periodic skeleton structure comprising of azimuthal actin rings connected via longitudinal spectrin tetramer filaments. This structure endows the axon with structural integrity and mechanical stability. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62c012e6ec31da4d90db018dde0ab158
https://doi.org/10.1101/2021.02.23.432468
https://doi.org/10.1101/2021.02.23.432468
A very successful model for simulating emergency evacuation is the social-force model. At the heart of the model is the self-driven force that is applied to an agent and is directed towards the exit. However, it is not clear if the application of thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e781dcbe4a40c18f5c1871bcc3c65ef2
http://arxiv.org/abs/2012.00065
http://arxiv.org/abs/2012.00065
Autor:
David M. Pierce, Vito Moreno, Eric Howard, George Lykotrafitis, Dennis Flanagan, Alessandro Fisher, Alen Uvalic, Carmen Ciardiello, Mark Rubano, Jyotsna Winsor
Publikováno v:
The Journal of oral implantology. 47(4)
When planning an implant-supported restoration, the dentist is faced with surgical and prosthetic technical issues as well as the patient's expectations. Many patients wish an immediate solution to an edentulous condition. This may be especially true