Zobrazeno 1 - 10
of 30
pro vyhledávání: '"George Luo"'
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-29 (2024)
Abstract Background The interpretation of large datasets, such as The Cancer Genome Atlas (TCGA), for scientific and research purposes, remains challenging despite their public availability. In this study, we focused on identifying gene expression pr
Externí odkaz:
https://doaj.org/article/8e73682728e244778e9742a2012680f4
Autor:
George Luo, Kristin Aldridge, Toby Chen, Vivek Aslot, Byung‐Gyu Kim, Eun Hyang Han, Neelima Singh, Sai Li, Tsan Sam Xiao, Michael B. Sporn, John J. Letterio
Publikováno v:
Molecular Oncology, Vol 17, Iss 12, Pp 2526-2545 (2023)
Synthetic oleanane triterpenoids (SOTs) are small molecules with broad anticancer properties. A recently developed SOT, 1‐[2‐cyano‐3,12‐dioxooleana‐1,9(11)‐dien‐28‐oyl]‐4(‐pyridin‐2‐yl)‐1H‐imidazole (CDDO‐2P‐Im or ‘2
Externí odkaz:
https://doaj.org/article/ea461143de2240b5ab41bd51465ba88f
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234955 (2020)
Coronavirus disease 2019 (COVID-19) started in Wuhan, China and has spread through other provinces and countries through infected travelers. On January 23rd, 2020, China issued a quarantine and travel ban on Wuhan because travelers from Wuhan were th
Externí odkaz:
https://doaj.org/article/27ce0afdc208421fafc466e99282b6b9
Autor:
George Luo, Kristin Aldridge, Toby Chen, Vivek Aslot, Byung‐Gyu Kim, Eun Hyang Han, Neelima Singh, Sai Li, Tsan Sam Xiao, Michael B. Sporn, John J. Letterio
Publikováno v:
Molecular Oncology.
Autor:
George Luo, Harshita Kumar, Kristin Aldridge, Stevie Rieger, Ethan Jiang, Ernest R. Chan, Ahmed Soliman, Haider Mahdi, John J. Letterio
Publikováno v:
bioRxiv
The Nrf2-KEAP1 pathway plays an important role in the cellular response to oxidative stress and confers protection in diseases associated with chronic inflammation. However, chronic activation of the Nrf2 pathway may contribute to metabolic changes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9a6e1c505d6cb3b53ffc864d634f80
https://europepmc.org/articles/PMC10153264/
https://europepmc.org/articles/PMC10153264/
Autor:
George Luo, John J. Letterio
Publikováno v:
bioRxiv
ObjectiveThere is a need for new methods to select and analyze cutoffs employed to define genes that are most prognostic significant and impactful. We designed LOCC (Luo’s Optimization Categorization Curve), a novel tool to visualize and score cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5542c6851ef35841c24e8052d705e9c6
https://doi.org/10.1101/2023.04.11.536461
https://doi.org/10.1101/2023.04.11.536461
Autor:
Ting Li, Jason R. Goldsmith, Honghong Sun, Youhai H. Chen, Xinyuan Li, Emily Eiler, George Luo, Wei Wang
Publikováno v:
Mol Immunol
Genome-wide association studies have established that human REL is a susceptibility gene for lymphoid cancers and inflammatory diseases. REL is the hematopoietic member of the nuclear factor-κB (NF-κB) family and is frequently amplified in human ly
Autor:
Qingguo Ruan, Sankar Ghosh, Emily Eiler, Weiyun Shi, Wei Wang, Xinyuan Li, Youhai H. Chen, Mingyue Li, Ramachandran Murali, Chin-Nien Lee, Ting Li, George Luo, Honghong Sun, Jian Jin, Ali Zamani
Publikováno v:
Nature Cancer. 1:507-517
Immunotherapy that targets lymphoid cell checkpoints holds great promise for curing cancer. However, many cancer patients do not respond to this form of therapy. In addition to lymphoid cells, myeloid cells play essential roles in controlling immunit
Recently, the antibody titer levels have been followed in 33 adults who received the mRNA-1273 vaccine for 6 months. With single dose estimated effectiveness of 92.1%, we combine this knowledge with corresponding antibody levels to model and estimate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9076e333be92d79fdd96d28407ad19a6
https://doi.org/10.1101/2021.05.04.21256537
https://doi.org/10.1101/2021.05.04.21256537
Autor:
Ehsan Malek, Sirisha Kundrapu, Stanton L. Gerson, Rebecca Ye, Naveed Ali, Nicolaus Kröger, George Luo, Marcos de Lima, Paolo Caimi, James J. Driscoll, Willem vanHeeckeren, Rose Beck, Ola Landgren
Publikováno v:
Clin Lymphoma Myeloma Leuk
Background High-dose chemotherapy and autologous stem cell transplantation (ASCT) are integral components of the overall treatment for patients with multiple myeloma (MM) aged ≤ 65 years. The emergence of oligoclonal immunoglobulin bands (ie, immun