Zobrazeno 1 - 6
of 6
pro vyhledávání: '"George Leonidis"'
Autor:
George Leonidis, Panagiotis Dalezis, Dimitrios Trafalis, Dimitris Beis, Panagiota Giardoglou, Anastasia Koukiali, Ioanna Sigala, Eleni Nikolakaki, Vasiliki Sarli
Publikováno v:
ACS Omega, Vol 6, Iss 42, Pp 28379-28393 (2021)
Externí odkaz:
https://doaj.org/article/c52815b334fd4fa7aa14abbd7d09cdf3
Autor:
George Leonidis, Anastasia Koukiali, Ioanna Sigala, Katerina Tsimaratou, Dimitris Beis, Thomas Giannakouros, Eleni Nikolakaki, Vasiliki Sarli
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 381 (2023)
Peptide–drug conjugates are delivery systems for selective delivery of cytotoxic agents to target cancer cells. In this work, the optimized synthesis of JH-VII-139-1 and its c(RGDyK) peptide conjugates is presented. The low nanomolar SRPK1 inhibito
Externí odkaz:
https://doaj.org/article/145fb83ef8474abaa6d3bbec6a46693f
Publikováno v:
Molecules, Vol 27, Iss 19, p 6632 (2022)
Cancer is one of the top leading causes of death worldwide. It is a heterogenous disease characterized by unregulated cell proliferation and invasiveness of abnormal cells. For the treatment of cancer, natural products have been widely used as a sour
Externí odkaz:
https://doaj.org/article/d24a29316caa4e9faa429bd46d4e0886
Autor:
Theodora Chatzisideri, George Leonidis, Theodoros Karampelas, Eleni Skavatsou, Angeliki Velentza-Almpani, Francesca Bianchini, Constantin Tamvakopoulos, Vasiliki Sarli
Publikováno v:
Journal of Medicinal Chemistry. 65:271-284
c(RGDyK)-based conjugates of gemcitabine (GEM) with the carbonate and carbamate linkages in the 6-OH group of GEM were synthesized for the targeted delivery of GEM to integrin α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce8d9bbffe24b7eefa8283c50b24c88a
https://doi.org/10.1021/acs.jmedchem.1c01468
https://doi.org/10.1021/acs.jmedchem.1c01468
Autor:
Theodora Chatzisideri, Francesca Bianchini, Panagiotis Dalezis, Dimitrios T. Trafalis, Vasiliki Sarli, Spyridon Bousis, George Leonidis
Publikováno v:
Future Medicinal Chemistry. 13:877-895
Cucurbitacins (CUCUs) are triterpenoids known to display potent cytotoxic effects; however, their clinical application is limited due to poor pharmacokinetics and systemic toxicity. This work focuses on the development of c(RGDyK)–CUCU conjugates f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5079274177a2236dfe51e8d554d9a4d
https://doi.org/10.4155/fmc-2020-0309
https://doi.org/10.4155/fmc-2020-0309
Publikováno v:
Future medicinal chemistry. 10(18)
There is a growing interest for the discovery of new cancer-targeted delivery systems for drug delivery and diagnosis. A synopsis of the bibliographic data will be presented on bombesin, neurotensin, octreotide, Arg-Gly-Asp, luteinizing hormone-relea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0318a9000f92e80e1ddc1823127cef0d
https://pubmed.ncbi.nlm.nih.gov/30043641
https://pubmed.ncbi.nlm.nih.gov/30043641