Zobrazeno 1 - 10
of 156
pro vyhledávání: '"George L. Scheffer"'
Autor:
Mariël Brinkhuis, Miguel A. Izquierdo, Jan P. A. Baak, Paul J. van Diest, Peter Kenemans, George L. Scheffer, Rik J. Scheper
Publikováno v:
Analytical Cellular Pathology, Vol 24, Iss 1, Pp 17-23 (2002)
Mean nuclear area has been consistently shown by different researchers to be a strong and independent prognostic factor in advanced ovarian carcinoma. However, the biological background of the prognostic value of nuclear area remains unclear. Others
Externí odkaz:
https://doaj.org/article/063b87e13418400283f07c28c323bff1
Autor:
Hans J. van der Vliet, Arnon P. Kater, Tanja D. de Gruijl, Paul W.H.I. Parren, Rob C. Roovers, Steven T. Pals, Mark-David Levin, Rieneke van de Ven, Anita G. Stam, Renate de Boer, Jana Vree, George L. Scheffer, Roeland Lameris, Iris de Weerdt
Supplementary Tables 1-2 and Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2362ee89f340190459bda2b8bdedcf43
https://doi.org/10.1158/2326-6066.22543959.v1
https://doi.org/10.1158/2326-6066.22543959.v1
Autor:
Hans J. van der Vliet, Arnon P. Kater, Tanja D. de Gruijl, Paul W.H.I. Parren, Rob C. Roovers, Steven T. Pals, Mark-David Levin, Rieneke van de Ven, Anita G. Stam, Renate de Boer, Jana Vree, George L. Scheffer, Roeland Lameris, Iris de Weerdt
Novel T cell–based therapies for the treatment of B-cell malignancies, such as chronic lymphocytic leukemia (CLL) and multiple myeloma (MM), are thought to have strong potential. Progress, however, has been hampered by low efficacy and high toxicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4993802098a95dc76dd88087515bd4dc
https://doi.org/10.1158/2326-6066.c.6550482
https://doi.org/10.1158/2326-6066.c.6550482
Autor:
Hans J. van der Vliet, Arnon P. Kater, Tanja D. de Gruijl, Paul W.H.I. Parren, Rob C. Roovers, Steven T. Pals, Mark-David Levin, Rieneke van de Ven, Anita G. Stam, Renate de Boer, Jana Vree, George L. Scheffer, Roeland Lameris, Iris de Weerdt
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b8e4bbf401445001ae70519575d61e
https://doi.org/10.1158/2326-6066.22543962.v1
https://doi.org/10.1158/2326-6066.22543962.v1
Autor:
John D. Schuetz, Christine A. Hrycyna, Karin F.K. Ejendal, Markos Leggas, Daxi Sun, Clinton F. Stewart, Masashi Adachi, George L. Scheffer, Jessica A. Morgan, Kazumasa Takenaka
Supplementary Figure 1 from Substrate Overlap between Mrp4 and Abcg2/Bcrp Affects Purine Analogue Drug Cytotoxicity and Tissue Distribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e127207c395542a5f4e1b48ceac93f24
https://doi.org/10.1158/0008-5472.22367756
https://doi.org/10.1158/0008-5472.22367756
Autor:
John D. Schuetz, Christine A. Hrycyna, Karin F.K. Ejendal, Markos Leggas, Daxi Sun, Clinton F. Stewart, Masashi Adachi, George L. Scheffer, Jessica A. Morgan, Kazumasa Takenaka
The use of probe substrates and combinations of ATP-binding cassette (ABC) transporter knockout (KO) animals may facilitate the identification of common substrates between apparently unrelated ABC transporters. An unexpectedly low concentration of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d64ffa600be423effc83f2bb6469e23
https://doi.org/10.1158/0008-5472.c.6495674
https://doi.org/10.1158/0008-5472.c.6495674
Autor:
John D. Schuetz, Christine A. Hrycyna, Karin F.K. Ejendal, Markos Leggas, Daxi Sun, Clinton F. Stewart, Masashi Adachi, George L. Scheffer, Jessica A. Morgan, Kazumasa Takenaka
Supplementary Table 1 from Substrate Overlap between Mrp4 and Abcg2/Bcrp Affects Purine Analogue Drug Cytotoxicity and Tissue Distribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd3bb7b0b685fcc0b252faa495d27e6
https://doi.org/10.1158/0008-5472.22367753
https://doi.org/10.1158/0008-5472.22367753
Autor:
Hans van Vliet, Paul W. H. I. Parren, Rieneke van de Ven, Jana Vree, Roeland Lameris, Tanja D. de Gruijl, Renate de Boer, Anita G.M. Stam, George L. Scheffer, Arnon P. Kater, Steven T. Pals, Mark-David Levin, Rob C. Roovers, Iris de Weerdt
Publikováno v:
Cancer immunology research, 9(1), 50-61. American Association for Cancer Research Inc.
Cancer Immunology Research, 9(1), 50-61. AMER ASSOC CANCER RESEARCH
de Weerdt, I, Lameris, R, Scheffer, G L, Vree, J, de Boer, R, Stam, A G, van de Ven, R, Levin, M-D, Pals, S T, Roovers, R C, Parren, P W H I, de Gruijl, T D, Kater, A P & van der Vliet, H J 2021, ' A Bispecific Antibody Antagonizes Prosurvival CD40 Signaling and Promotes Vγ9Vδ2 T cell-Mediated Antitumor Responses in Human B-cell Malignancies ', Cancer Immunology Research, vol. 9, no. 1, pp. 50-61 . https://doi.org/10.1158/2326-6066.CIR-20-0138
Cancer Immunology Research, 9(1), 50-61. American Association for Cancer Research Inc.
Cancer Immunology Research, 9(1), 50-61. AMER ASSOC CANCER RESEARCH
de Weerdt, I, Lameris, R, Scheffer, G L, Vree, J, de Boer, R, Stam, A G, van de Ven, R, Levin, M-D, Pals, S T, Roovers, R C, Parren, P W H I, de Gruijl, T D, Kater, A P & van der Vliet, H J 2021, ' A Bispecific Antibody Antagonizes Prosurvival CD40 Signaling and Promotes Vγ9Vδ2 T cell-Mediated Antitumor Responses in Human B-cell Malignancies ', Cancer Immunology Research, vol. 9, no. 1, pp. 50-61 . https://doi.org/10.1158/2326-6066.CIR-20-0138
Cancer Immunology Research, 9(1), 50-61. American Association for Cancer Research Inc.
Novel T cell-based therapies for the treatment of B-cell malignancies, such as chronic lymphocytic leukemia (CLL) and multiple myeloma (MM), are thought to have strong potential. Progress, however, has been hampered by low efficacy and high toxicity.
Autor:
Rieneke van de Ven, J.W. van der Heijden, R.J. Scheper, B A C Dijkmans, G.J. Peters, Gerrit Jansen, George L. Scheffer, Ruud Oerlemans, Marjolein Blits, W.F. Lems, Yehuda G. Assaraf
Publikováno v:
Oerlemans, R, Blits, M, Dijkmans, BAC, van der Heijden, JW, Lems, WF, Scheffer, GL, van de Ven, R, Peters, GJ, Assaraf, Y G, Scheper, RJ & Jansen, G 2020, ' Expression profiling of ABC transporters in peripheral blood lymphocytes and monocyte-derived macrophages of rheumatoid arthritis patients ', Journal of Molecular and Clinical Medicine, vol. 3, no. 2, 2020.02.007, pp. 47-60 . https://doi.org/10.31083/j.jmcm.2020.02.007
Journal of Molecular and Clinical Medicine, 3(2):2020.02.007, 47-60
Journal of Molecular and Clinical Medicine, 3(2):2020.02.007, 47-60
In autoimmune diseases like rheumatoid arthritis (RA), multidrug resistance (MDR) transporters of the ATP-binding cassette (ABC) transporter superfamily harbor dual functions by extruding pro-inflammatory mediators and exporting disease modifying ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0065cb71d6b80f0bb82bb431f8d08e92
https://research.vumc.nl/en/publications/9da1945b-c0d2-4f5c-a658-dc382a6e644c
https://research.vumc.nl/en/publications/9da1945b-c0d2-4f5c-a658-dc382a6e644c
Autor:
Rik J. Scheper, Sue Ellen Verbrugge, Yehuda G. Assaraf, Huib Ovaa, Gerrit Jansen, Robert H. Shoemaker, Godefridus J. Peters, Rob H. Meloen, Ruud Oerlemans, Celia R. Berkers, George L. Scheffer, Jacqueline Cloos, Jerry W. Slootstra, Ben A. C. Dijkmans
Publikováno v:
Investigational New Drugs
Oerlemans, R, Berkers, C R, Assaraf, Y G, Scheffer, G L, Peters, G J, Verbrugge, S E, Cloos, J, Slootstra, J, Meloen, R H, Shoemaker, R H, Dijkmans, B A C, Scheper, R J, Ovaa, H & Jansen, G 2018, ' Proteasome inhibition and mechanism of resistance to a synthetic, library-based hexapeptide ', Investigational New Drugs, vol. 36, no. 5, pp. 797-809 . https://doi.org/10.1007/s10637-018-0569-x
Investigational New Drugs, 36(5), 797-809. Kluwer Academic Publishers
Investigational New Drugs, 36(5), 797-809
Oerlemans, R, Berkers, C R, Assaraf, Y G, Scheffer, G L, Peters, G J, Verbrugge, S E, Cloos, J, Slootstra, J, Meloen, R H, Shoemaker, R H, Dijkmans, B A C, Scheper, R J, Ovaa, H & Jansen, G 2018, ' Proteasome inhibition and mechanism of resistance to a synthetic, library-based hexapeptide ', Investigational New Drugs, vol. 36, no. 5, pp. 797-809 . https://doi.org/10.1007/s10637-018-0569-x
Investigational New Drugs, 36(5), 797-809. Kluwer Academic Publishers
Investigational New Drugs, 36(5), 797-809
Summary Background The hexapeptide 4A6 (Ac-Thr(tBu)-His(Bzl)-Thr(Bzl)-Nle-Glu(OtBu)-Gly-Bza) was isolated from a peptide library constructed to identify peptide-based transport inhibitors of multidrug resistance (MDR) efflux pumps including P-glycopr