Zobrazeno 1 - 10
of 16
pro vyhledávání: '"George L. Clemmer"'
Autor:
Michael J. McGeachie, George L. Clemmer, Jessica Lasky-Su, Amber Dahlin, Benjamin A. Raby, Scott T. Weiss
Publikováno v:
Genomics Data, Vol 2, Iss C, Pp 202-211 (2014)
We show here that combining two existing genome wide association studies (GWAS) yields additional biologically relevant information, beyond that obtained by either GWAS separately. We propose Joint GWAS Analysis, a method that compares a pair of GWAS
Externí odkaz:
https://doaj.org/article/4b1c0ece62264849854c9868d251eaea
Autor:
Jessica Lasky-Su, Peter J. Castaldi, Michael J. McGeachie, Joanne E. Sordillo, Michael H. Cho, George L. Clemmer, Damien C. Croteau-Chonka, Benjamin A. Raby, Kelan G. Tantisira, Scott T. Weiss
Publikováno v:
Immunity, Inflammation and Disease
Introduction While whole genome prediction (WGP) methods have recently demonstrated successes in the prediction of complex genetic diseases, they have not yet been applied to asthma and related phenotypes. Longitudinal patterns of lung function diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9832f87fb83841ebbee3dc14b99146d3
https://doi.org/10.1002/iid3.133
https://doi.org/10.1002/iid3.133
Autor:
Scott T. Weiss, Amber Dahlin, George L. Clemmer, John Ziniti, Kelan G. Tantisira, Ann Chen Wu, Peter Weeke, Christian M. Shaffer, Murray H. Brilliant, Mayumi Tamari, James G. Linneman, Joshua C. Denny, Terrie Kitchner, Michiaki Kubo, Michael J. McGeachie, Dan M. Roden, Christie Ingram, Hua Xu
Publikováno v:
Immunity, Inflammation and Disease
Inhaled corticosteroids (ICS) are the most effective controller medications for asthma, and variability in ICS response is associated with genetic variation. Despite ICS treatment, some patients with poor asthma control experience severe asthma exace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2191a2ce6a5bfa76bdafa21af660e8
http://europepmc.org/articles/PMC4693729
http://europepmc.org/articles/PMC4693729
Autor:
Jessica Lasky-Su, George L. Clemmer, Michael J. McGeachie, Benjamin A. Raby, Scott T. Weiss, Amber Dahlin
Publikováno v:
Genomics Data
Genomics Data, Vol 2, Iss C, Pp 202-211 (2014)
Genomics Data, Vol 2, Iss C, Pp 202-211 (2014)
We show here that combining two existing genome wide association studies (GWAS) yields additional biologically relevant information, beyond that obtained by either GWAS separately. We propose Joint GWAS Analysis, a method that compares a pair of GWAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c196424b2fd6a2338b985e66e3a26e9c
Autor:
Scott T. Weiss, Heming Xing, Ann Chen Wu, Kelan G. Tantisira, Michael J. McGeachie, Quan Lu, Bruce W. Church, Boris Hayete, Karl Runge, Iya Khalil, George L. Clemmer, Xiaofeng Jiang
Publikováno v:
The Journal of allergy and clinical immunology. 142(5)
Background Variation in response to the most commonly used class of asthma controller medication, inhaled corticosteroids, presents a serious challenge in asthma management, particularly for steroid-resistant patients with little or no response to tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c20c2b76b10fdc126a406281716b80
https://pubmed.ncbi.nlm.nih.gov/29410046
https://pubmed.ncbi.nlm.nih.gov/29410046
Autor:
Paul Geeleher, Mark J. Ratain, Scott T. Weiss, Julian Solway, Eric R. Gamazon, Hae Kyung Im, Steven R. White, Kelan G. Tantisira, George L. Clemmer, Nancy J. Cox, Kehua Wu, R. Stephanie Huang
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 190:619-627
Most genomic studies of lung function have used phenotypic data derived from a single time-point (e.g., presence/absence of disease) without considering the dynamic progression of a chronic disease.To characterize lung function change over time in su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db843d6e3c44efb631b50e7da7dc7a0
https://doi.org/10.1164/rccm.201403-0460oc
https://doi.org/10.1164/rccm.201403-0460oc
Autor:
Augusto A. Litonjua, Scott T. Weiss, Ann Chen Wu, George L. Clemmer, Kelan G. Tantisira, Michael J. McGeachie, Bernard Rosner
Publikováno v:
The Journal of allergy and clinical immunology. 136(2)
Background Inhaled corticosteroids are the most commonly used controller therapies for asthma, producing treatment responses in 6 clinical phenotypes: lung function, bronchodilator response, airway responsiveness, symptoms, need for oral steroids and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09255500f4f302e55508fab2a3aae04b
https://pubmed.ncbi.nlm.nih.gov/25951964
https://pubmed.ncbi.nlm.nih.gov/25951964
Autor:
George L. Clemmer, Dan M. Roden, Benjamin A. Raby, Scott T. Weiss, Joanne E. Sordillo, Josh C. Denny, Robert P. Chase, Michael J. McGeachie, Kelan G. Tantisira, Ann Chen Wu, Hua Xu, Peter Weeke, Fernando D. Martinez, Reynold A. Panettieri, Christian M. Shaffer, Blanca E. Himes, Sze Man Tse, Jessica Lasky-Su
Publikováno v:
The Journal of allergy and clinical immunology. 136(6)
Background Asthma exacerbations are a major cause of morbidity and medical cost. Objective The objective of this study was to identify genetic predictors of exacerbations in asthmatic subjects. Methods We performed a genome-wide association study met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae6a190cf4ca927291a8cd18dc67aa5
https://pubmed.ncbi.nlm.nih.gov/26073756
https://pubmed.ncbi.nlm.nih.gov/26073756
Autor:
McGeachie, Michael J.1 remmg@channing.harvard.edu, Clemmer, George L.1, Croteau‐Chonka, Damien C.1, Castaldi, Peter J.1, Cho, Michael H.1, Sordillo, Joanne E.1, Lasky‐Su, Jessica A.1, Raby, Benjamin A.1, Tantisira, Kelan G.1, Weiss, Scott T.1
Publikováno v:
Immunity, Inflammation & Disease. Dec2016, Vol. 4 Issue 4, p487-496. 10p.
Autor:
Dahlin, Amber1, Denny, Joshua2,3, Roden, Dan M.4, Brilliant, Murray H.5, Ingram, Christie3, Kitchner, Terrie E.5, Linneman, James G.6, Shaffer, Christian M.3, Weeke, Peter3,7, Xu, Hua8, Kubo, Michiaki9, Tamari, Mayumi9, Clemmer, George L.1, Ziniti, John1, McGeachie, Michael J.1, Tantisira, Kelan G.1, Weiss, Scott T.1, Wu, Ann Chen1,10
Publikováno v:
Immunity, Inflammation & Disease. Dec2015, Vol. 3 Issue 4, p350-359. 10p.