Zobrazeno 1 - 6
of 6
pro vyhledávání: '"George Kweifio-Okai"'
Publikováno v:
Molecular and Cellular Biochemistry. 252:97-101
Lupeol-3-palmitate (LP) and lupeol-3-linoleate (LL), two synthetic long chain fatty acid ester analogues of the plant-derived anti-inflammatory pentacyclic triterpenoid lupeol (L), were studied in vitro as potential inhibitors of serine protease acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1df98550ad0321b2efa7e72517c68333
https://doi.org/10.1023/a:1025569805468
https://doi.org/10.1023/a:1025569805468
Autor:
Antonio Rajic, Gideon M. Polya, Theodore A. Macrides, David Chandler, George Kweifio-Okai, Richard Mark Sandeman
Publikováno v:
Planta Medica. 66:206-210
The lupane triterpenoid lupeol, the ursane triterpenoid alpha-amyrin and esters of these compounds are present in the bark of roots of Alstonia boonei (Apocynaceae) and have anti-inflammatory properties. alpha-Amyrin is a competitive inhibitor of bov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e45a59b4027b42cc2c105309573a12d
https://doi.org/10.1055/s-2000-8657
https://doi.org/10.1055/s-2000-8657
Publikováno v:
Planta Medica. 65:014-018
The ursane triterpenoid alpha-amyrin and the lupane triterpenoid lupeol are potent inhibitors of the catalytic subunit (cAK) of rat liver cyclic AMP-dependent protein kinase (PKA) with IC50 values of 8 and 5 microM, respectively. The palmitate and li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780cef1136dad3a896019ca48d072b7f
https://doi.org/10.1055/s-1999-13954
https://doi.org/10.1055/s-1999-13954
Publikováno v:
Drug Development Research. 36:20-24
The triterpenes lupeol (L), lupeol-3-palmitate (LP), and lupeol-3-linoleate (LL) have previously been shown to reduce joint destruction in adjuvant arthritic rats. In order to explain the relative antiarthritic effectiveness (LL>LP>L), the triterpene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f63d5cd9ad18686da2d1d60ba229945
https://doi.org/10.1002/ddr.430360104
https://doi.org/10.1002/ddr.430360104
Publikováno v:
Drug Development Research. 35:137-141
Adult male Wistar rats were made arthritic by the subplantar injection of complete Freund's adjuvant. Oral treatment with the triterpenes lupeol, luepol palmitate, or lupeol linoleate (66 mg/kg BW every 2 days) from days 24 to 32 reduced synovial gra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dc92eba54877b2bb4ed5f44931c492b
https://doi.org/10.1002/ddr.430350304
https://doi.org/10.1002/ddr.430350304
Publikováno v:
Molecular and cellular biochemistry. 252(1-2)
Lupeol-3-palmitate (LP) and lupeol-3-linoleate (LL), two synthetic long chain fatty acid ester analogues of the plant-derived anti-inflammatory pentacyclic triterpenoid lupeol (L), were studied in vitro as potential inhibitors of serine protease acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55234f7c5482b1059e063444ac7fe2f9
https://pubmed.ncbi.nlm.nih.gov/14577581
https://pubmed.ncbi.nlm.nih.gov/14577581