Zobrazeno 1 - 10
of 27
pro vyhledávání: '"George Kritikos"'
Autor:
Anthony L Shiver, Hendrik Osadnik, George Kritikos, Bo Li, Nevan Krogan, Athanasios Typas, Carol A Gross
Publikováno v:
PLoS Genetics, Vol 13, Iss 7, p e1006902 (2017)
[This corrects the article DOI: 10.1371/journal.pgen.1006124.].
Externí odkaz:
https://doaj.org/article/891df7df3c68438897b9d9817b4d28a0
Autor:
Anthony L Shiver, Hendrik Osadnik, George Kritikos, Bo Li, Nevan Krogan, Athanasios Typas, Carol A Gross
Publikováno v:
PLoS Genetics, Vol 12, Iss 6, p e1006124 (2016)
Fighting antibiotic resistance requires a deeper understanding of the genetic factors that determine the antibiotic susceptibility of bacteria. Here we describe a chemical-genomic screen in Escherichia coli K-12 that was designed to discover new aspe
Externí odkaz:
https://doaj.org/article/9969ea02cb364226a0cce984a9238914
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004056 (2014)
The cell envelope of Gram-negative bacteria is a formidable barrier that is difficult for antimicrobial drugs to penetrate. Thus, the list of treatments effective against these organisms is small and with the rise of new resistance mechanisms is shri
Externí odkaz:
https://doaj.org/article/ac59dc3744a24142b55b5b8a322e4941
Autor:
Jacob Bobonis, Karin Mitosch, André Mateus, Nicolai Karcher, George Kritikos, Joel Selkrig, Matylda Zietek, Vivian Monzon, Birgit Pfalz, Sarela Garcia-Santamarina, Marco Galardini, Anna Sueki, Callie Kobayashi, Frank Stein, Alex Bateman, Georg Zeller, Mikhail M. Savitski, Johanna R. Elfenbein, Helene L. Andrews-Polymenis, Athanasios Typas
Publikováno v:
Nature. 609:144-150
Publikováno v:
Bioinformatics. 39
Motivation High-throughput chemical genomic screens produce informative datasets, providing valuable insights into unknown gene function on a genome-wide level. However, there is currently no comprehensive analytic package publicly available. We deve
High-throughput chemical genomic screens produce informative datasets, providing valuable insights into unknown gene function on a genome-wide level. However, there is currently no comprehensive analytic package publicly available. We developed and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::694425ae61dbaaed3176758bf296c19c
https://doi.org/10.1101/2023.01.05.522861
https://doi.org/10.1101/2023.01.05.522861
Autor:
Shu-Sin Chng, Faye C. Morris, Gabriela Boelter, Richard W. Meek, Manuel Banzhaf, George Kritikos, Andrew L. Lovering, Yanina R. Sevastsyanovich, Jack A. Bryant, Ian R. Henderson, Adam F. Cunningham, Zhi-Soon Chong, Ian T. Cadby
Publikováno v:
Journal of Bacteriology
M48 metalloproteases are widely distributed in all domains of life. E. coli possesses four members of this family located in multiple cellular compartments. The functions of these proteases are not well understood. Recent investigations revealed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0919495f77046a01af99a65c178acc3b
https://doi.org/10.1101/2020.07.30.230011
https://doi.org/10.1101/2020.07.30.230011
Autor:
Jacob Bobonis, André Mateus, Mikhail M. Savitski, George Kritikos, Elfenbein, Athanasios Typas, Karin Mitosch, Helene Andrews-Polymenis
Bacteria carry dozens of Toxin/Antitoxin systems (TAs) in their chromosomes. Upon growth, the antitoxin is co-expressed and neutralizes the toxin. TAs can be activated and inhibit growth, but when and how this occurs has largely remained enigmatic, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32877382a3ba2cbb52ab39c6110dbd5b
https://doi.org/10.1101/2020.06.22.160242
https://doi.org/10.1101/2020.06.22.160242
Autor:
Jacob, Bobonis, Karin, Mitosch, André, Mateus, Nicolai, Karcher, George, Kritikos, Joel, Selkrig, Matylda, Zietek, Vivian, Monzon, Birgit, Pfalz, Sarela, Garcia-Santamarina, Marco, Galardini, Anna, Sueki, Callie, Kobayashi, Frank, Stein, Alex, Bateman, Georg, Zeller, Mikhail M, Savitski, Johanna R, Elfenbein, Helene L, Andrews-Polymenis, Athanasios, Typas
Publikováno v:
Nature. 609(7925)
Retrons are prokaryotic genetic retroelements encoding a reverse transcriptase that produces multi-copy single-stranded DNA
Autor:
Manuel Banzhaf, Laura M. Sanchez, George Kritikos, Gabriela Boelter, Lars E. P. Dietrich, Lisa Juliane Kahl, Alanna R. Condren
Publikováno v:
ACS infectious diseases, vol 6, iss 4
Biofilm inhibition by exogenous molecules has been an attractive strategy for the development of novel therapeutics. We investigated the biofilm inhibitor taurolithocholic acid (TLCA) and its effects on the specialized metabolism, virulence, and biof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47a58e36abfc6a615e61a3f296438d1
https://escholarship.org/uc/item/64q3t7m4
https://escholarship.org/uc/item/64q3t7m4