Zobrazeno 1 - 10
of 69
pro vyhledávání: '"George Kontopidis"'
Autor:
Vagelis Rinotas, Fotini Liepouri, Maria-Dimitra Ouzouni, Niki Chalkidi, Christos Papaneophytou, Mariza Lampropoulou, Veroniki P. Vidali, George Kontopidis, Elias Couladouros, Elias Eliopoulos, Athanasios Papakyriakou, Eleni Douni
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11290 (2023)
Receptor activator of nuclear factor-κB ligand (RANKL) has been actively pursued as a therapeutic target for osteoporosis, given that RANKL is the master mediator of bone resorption as it promotes osteoclast differentiation, activity and survival. W
Externí odkaz:
https://doaj.org/article/cb92f8a3149b4567b5e13334ae577140
Autor:
Georgia Melagraki, Evangelos Ntougkos, Vagelis Rinotas, Christos Papaneophytou, Georgios Leonis, Thomas Mavromoustakos, George Kontopidis, Eleni Douni, Antreas Afantitis, George Kollias
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 4, p e1005372 (2017)
We present an in silico drug discovery pipeline developed and applied for the identification and virtual screening of small-molecule Protein-Protein Interaction (PPI) compounds that act as dual inhibitors of TNF and RANKL through the trimerization in
Externí odkaz:
https://doaj.org/article/bb8badfc680d46728e9988d005f3b0c7
Autor:
Douni, Vagelis Rinotas, Fotini Liepouri, Maria-Dimitra Ouzouni, Niki Chalkidi, Christos Papaneophytou, Mariza Lampropoulou, Veroniki P. Vidali, George Kontopidis, Elias Couladouros, Elias Eliopoulos, Athanasios Papakyriakou, Eleni
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 14; Pages: 11290
Receptor activator of nuclear factor-κB ligand (RANKL) has been actively pursued as a therapeutic target for osteoporosis, given that RANKL is the master mediator of bone resorption as it promotes osteoclast differentiation, activity and survival. W
Autor:
Olga S.E. Papaioannou, Aikaterini C. Tsika, Magdalini Rovoli, Georgios E. Papadopoulos, George Kontopidis, Georgios A. Spyroulias, Demetres D. Leonidas
Publikováno v:
Biochemistry.
Publikováno v:
GSC Advanced Research and Reviews. 6:029-034
Lameness in pigs is a major welfare and economic issue for swine breeding herds. Claw lesions have been suggested to be a significant cause for lameness in sows. Housing conditions and nutrition management on the farm influence horn quality and may b
Publikováno v:
IEEE Antennas and Wireless Propagation Letters. 18:1512-1516
Optically transparent antenna arrays create opportunities to deploy communication systems in more diverse locations due to their transparency and ability to steer energy. We present horizontally and vertically polarized, optically transparent antenna
Autor:
Sandra Braun, Michael Röring, Campbell McInnes, Simeon Galda, Tilman Brummer, Chad M Beneker, Magdalini Rovoli, George Kontopidis
Publikováno v:
Journal of Medicinal Chemistry. 62:3886-3897
Despite the clinical success of BRAF inhibitors like vemurafenib in treating metastatic melanoma, resistance has emerged through "paradoxical MEK/ERK signaling" where transactivation of one protomer occurs as a result of drug inhibition of the other
Autor:
George Kontopidis, Polyxeni Alexiou, Elias Eliopoulos, Alexandros T. Strongilos, Elias A. Couladouros, Christos Papaneophytou, Vagelis Rinotas, Foteini Violitzi, Eleni Douni, Maria Dimitra Ouzouni, Athanasios Papakyriakou
Publikováno v:
Journal of medicinal chemistry. 63(20)
Receptor activator of nuclear factor-κB ligand (RANKL) constitutes the master mediator of osteoclastogenesis, while its pharmaceutical inhibition by a monoclonal antibody has been approved for the treatment of postmenopausal osteoporosis. To date, t
Autor:
Anna Maranti, George Kontopidis, Christos Papaneophytou, Anthi Mettou, Antreas Afantitis, Polyxeni Alexiou, Elias Eliopoulos, Elias A. Couladouros, Fotini Liepouri, Georgia Melagraki, Athanasios Papakyriakou
Publikováno v:
SLAS Discovery. 23:84-93
The aim of this study is to improve the aqueous solubility of a group of compounds without interfering with their bioassay as well as to create a relevant prediction model. A series of 55 potential small-molecule inhibitors of tumor necrosis factor-a
Publikováno v:
Journal of liposome research. 29(2)
Vitamin A (VA) is an essential nutrient needed in small amounts by humans and supports a wide range of biological actions. Retinol, the most common and most biologically active form of VA has also been found to inhibit peroxidation processes in membr