Zobrazeno 1 - 10
of 155
pro vyhledávání: '"George K. Christophides"'
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-15 (2021)
Abstract Background Whole genome re-sequencing provides powerful data for population genomic studies, allowing robust inferences of population structure, gene flow and evolutionary history. For the major malaria vector in Africa, Anopheles gambiae, o
Externí odkaz:
https://doaj.org/article/4f15c00d6447473e8027574235612552
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-8 (2021)
Abstract Background Understanding malaria vector’s population dynamics and their spatial distribution is important to define when and where the largest infection risks occur and implement appropriate control strategies. In this study, the seasonal
Externí odkaz:
https://doaj.org/article/8c6cd4d552b94c62b5358f606d8e513c
Autor:
Tibebu Habtewold, Aayushi A. Sharma, Claudia A. S. Wyer, Ellen K. G. Masters, Nikolai Windbichler, George K. Christophides
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Malaria parasites develop as oocysts in the mosquito for several days before they are able to infect a human host. During this time, mosquitoes take bloodmeals to replenish their nutrient and energy reserves needed for flight and reproductio
Externí odkaz:
https://doaj.org/article/c8442e288403435e844c9b9145d7d43b
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-9 (2020)
Abstract Background Malaria vector mosquitoes acquire midgut microbiota primarily from their habitat. The homeostasis of these microbial communities plays an essential role in the mosquito longevity, the most essential factor in the mosquito vectoria
Externí odkaz:
https://doaj.org/article/3d6c30e56b8848048f9531a783e0eda9
Autor:
Tibebu Habtewold, Sofia Tapanelli, Ellen K. G. Masters, Nikolai Windbichler, George K. Christophides
Publikováno v:
PLoS ONE, Vol 17, Iss 12 (2022)
Key behaviours, physiologies and gene expressions in Anopheles mosquitoes impact the transmission of Plasmodium. Such mosquito factors are rhythmic to closely follow diel rhythms. Here, we set to explore the impact of the mosquito circadian rhythm on
Externí odkaz:
https://doaj.org/article/53d7de499cb6411db493405a25ba888d
Publikováno v:
Parasites & Vectors, Vol 12, Iss 1, Pp 1-8 (2019)
Abstract Background Vector control remains the most important tool to prevent malaria transmission. However, it is now severely constrained by the appearance of physiological and behavioral insecticide resistance. Therefore, the development of new ve
Externí odkaz:
https://doaj.org/article/b1ac2c943e79483fac54f4cb9884c073
Autor:
Tibebu Habtewold, Sofia Tapanelli, Ellen K. G. Masters, Astrid Hoermann, Nikolai Windbichler, George K. Christophides
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-11 (2019)
Abstract Background The development of malaria transmission-blocking strategies including the generation of malaria refractory mosquitoes to replace the wild populations through means of gene drives hold great promise. The standard membrane feeding a
Externí odkaz:
https://doaj.org/article/31022306460f4a268da65420c208390f
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Plasmodium falciparum malaria remains a major cause of global morbidity and mortality, mainly in sub-Saharan Africa. The numbers of new malaria cases and deaths have been stable in the last years despite intense efforts for disease elimination, highl
Externí odkaz:
https://doaj.org/article/4e7cbd1bb9ad43dc910e5cf3e80579cc
Autor:
Chiamaka Valerie Ukegbu, Maria Giorgalli, Hassan Yassine, Jose Luis Ramirez, Chrysanthi Taxiarchi, Carolina Barillas-Mury, George K. Christophides, Dina Vlachou
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Malaria is a mosquito-borne disease affecting millions of people every year. The rodent parasite Plasmodium berghei has served as a model for human malaria transmission studies and played a pivotal role in dissecting the mosquito immune resp
Externí odkaz:
https://doaj.org/article/c035f05e477f48ec99621db1c9d2917f
Publikováno v:
Parasites & Vectors, Vol 10, Iss 1, Pp 1-12 (2017)
Abstract Background The Anopheles gambiae complex consists of species that vary greatly in their capacity to transmit malaria. The mosquito immune system has been identified as a key factor that can influence whether Plasmodium infection establishes
Externí odkaz:
https://doaj.org/article/e46c96017f424275b810ff2513414607