Zobrazeno 1 - 10
of 15
pro vyhledávání: '"George K. Chandy"'
Autor:
Ricardo C. H. del Rosario, Jeremie Poschmann, Carey Lim, Catherine Y. Cheng, Pavanish Kumar, Catherine Riou, Seow Theng Ong, Sherif Gerges, Hajira Shreen Hajan, Dilip Kumar, Mardiana Marzuki, Xiaohua Lu, Andrea Lee, Giovani Claresta Wijaya, Nirmala Arul Rayan, Zhong Zhuang, Elsa Du Bruyn, Cynthia Bin Eng Chee, Bernett Lee, Josephine Lum, Francesca Zolezzi, Michael Poidinger, Olaf Rotzschke, Chiea Chuen Khor, Robert J. Wilkinson, Yee T. Wang, George K Chandy, Gennaro De Libero, Amit Singhal, Shyam Prabhakar
Publikováno v:
Nature Microbiology. 7:312-326
Host cell chromatin changes are thought to play an important role in the pathogenesis of infectious diseases. Here we describe a histone acetylome-wide association study (HAWAS) of an infectious disease, on the basis of genome-wide H3K27 acetylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cba6e02a98bc4c02a1b4883ab2a1101
https://doi.org/10.1038/s41564-021-01049-w
https://doi.org/10.1038/s41564-021-01049-w
Autor:
Ricardo C. H. del Rosario, Jeremie Poschmann, Carey Lim, Catherine Y. Cheng, Pavanish Kumar, Catherine Riou, Seow Theng Ong, Sherif Gerges, Hajira Shreen Hajan, Dilip Kumar, Mardiana Marzuki, Xiaohua Lu, Andrea Lee, Giovani Claresta Wijaya, Nirmala Arul Rayan, Zhong Zhuang, Elsa Du Bruyn, Cynthia Bin Eng Chee, Bernett Lee, Josephine Lum, Francesca Zolezzi, Michael Poidinger, Olaf Rotzschke, Chiea Chuen Khor, Robert J. Wilkinson, Yee T. Wang, George K Chandy, Gennaro De Libero, Amit Singhal, Shyam Prabhakar
Publikováno v:
Nature Microbiology
Nature Microbiology, 2022, 7 (11), pp.1943-1943. ⟨10.1038/s41564-022-01236-3⟩
Nature Microbiology, 2022, 7 (11), pp.1943-1943. ⟨10.1038/s41564-022-01236-3⟩
International audience; No abstract available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631f2ae1222c3a56417fce3d4b647c0f
https://www.hal.inserm.fr/inserm-03872115/document
https://www.hal.inserm.fr/inserm-03872115/document
Autor:
Raymond S. Norton, George K. Chandy
Publikováno v:
Current Opinion in Chemical Biology. 38:97-107
The voltage-gated Kv1.3 channel in T lymphocytes is a validated therapeutic target for diverse autoimmune diseases. Here we review the discovery of Kv1.3, its physiological role in T cells, and why it is an attractive target for modulating autoimmune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26413158722a8892f39ec509eb992bc0
https://doi.org/10.1016/j.cbpa.2017.02.015
https://doi.org/10.1016/j.cbpa.2017.02.015
Autor:
Serdar Kuyucak, Shih Chieh Chang, Dharmeshkumar Patel, Boominathan Ramasamy, George K. Chandy, Xuan Rui Ng, Jeremy Jun Heng Ng, Saumya Bajaj, Janna Bednenko, Rodrigo Av Morales, Seow Theng Ong, Hai M. Nguyen, Julien Lescar, Christine Beeton, Pragalath Sadasivam, Julian L. Goggi, Paul A. Colussi, Susan A. Charman, Rahul Patil, Bankala Krishnarjuna, Sanling Liu, Wen Tan Peng, Yue Zhao, Mark R. Tanner, Heike Wulff, Hartimath Sv, Longhua Zhang, Wei Chen Ming, Sabina Yasmin, Edward G. Robins, Changlin Tian, Vikas Dhawan, Raymond S. Norton, Michael W. Pennington, El Sahili Abbas, Yong Zhang, Dahai Luo
Publikováno v:
SSRN Electronic Journal.
Author(s): Ong, Seow Theng; Liu, Sanling; Bajaj, Saumya; Zhao, Yue; Tanner, Mark R; Chang, Shih Chieh; Zhang, Yong; Krishnarjuna, Bankala; Ng, Xuan Rui; Morales, Rodrigo AV; Ming, Wei Chen; Luo, Dahai; Patel, Dharmeshkumar; Yasmin, Sabina; Ng, Jeremy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d00fcf1fc6794220e65e7ec716f130d0
https://doi.org/10.2139/ssrn.3467250
https://doi.org/10.2139/ssrn.3467250
Autor:
Tanima Bose, Subbu S. Venkatraman, Aihua Hou, Louis Tong, Yuan Siang Lui, George K. Chandy, Yingying Huang, Jie Liang Phua
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2977 (2018)
Volume 19
Issue 10
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2977 (2018)
Volume 19
Issue 10
Topical ophthalmologic treatments have been facing great challenges with main limitations of low drug bioavailability, due to highly integrative defense mechanisms of the eye. This study rationally devised strategies to increase drug bioavailability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d78b53061be79f7fb4f4fcc8341f83
http://europepmc.org/articles/PMC6213297
http://europepmc.org/articles/PMC6213297
Autor:
Vikas Dhawan, George K. Chandy, Satendra Chauhan, James D. Swarbrick, Shihchieh Jeff Chang, Mariel Gindin, Hai M. Nguyen, Luz M. Londono, Biswaranjan Mohanty, Rosendo Estrada, Sanjeev K. Upadhyay, Heike Wulff, Sandeep Chhabra, Mark R. Tanner, George A. Gutman, Jesus G. Valenzuela, Christine Beeton, Raymond S. Norton, Michael W. Pennington, Redwan Huq, Shawn P. Iadonato, Peter J. Hotez
Publikováno v:
Chhabra, S; Chang, SC; Nguyen, HM; Huq, R; Tanner, MR; Londono, LM; et al.(2014). Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: Implications for autoimmune diseases. FASEB Journal, 28(9), 3952-3964. doi: 10.1096/fj.14-251967. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/7263j9v0
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol 28, iss 9
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol 28, iss 9
© FASEB. The voltage-gated potassium (Kv) 1.3 channel is widely regarded as a therapeutic target for immunomodulation in autoimmune diseases. ShK-186, a selective inhibitor of Kv1.3 channels, ameliorates autoimmune diseases in rodent models, and hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156094e78816a581e3ee1acc175ae688
https://doi.org/10.1096/fj.14-251967
https://doi.org/10.1096/fj.14-251967
Autor:
Sabina Yasmin, Raymond S. Norton, Jeff Chang, Dharmesh Patel, George K. Chandy, Chen Ming Wei, Michael W. Pennington, Mark R. Tanner, Yanxia Tang, Krishnarjuna Bankula, Rodrigo A.V. Morales, Luo Dahai, Serdar Kuyucak, Christine Beeton
Publikováno v:
Toxicon. 158:S36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::872a31d9b8e81b32d9378539258547a5
https://doi.org/10.1016/j.toxicon.2018.10.127
https://doi.org/10.1016/j.toxicon.2018.10.127
Publikováno v:
Cellular Physiology and Biochemistry. 7:135-147
The Kv1.3 potassium channel in T lymphocytes plays a major role in mitogen-induced activation and is widely recognized as a potential therapeutic target for immunosuppressive agents. Availability of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f599e991b9ecb6dc5d7deabf7645eb4
https://doi.org/10.1159/000154868
https://doi.org/10.1159/000154868
Publikováno v:
Cellular and molecular life sciences : CMLS. 71(7)
MMP23 is a member of the matrix metalloprotease family of zinc- and calcium-dependent endopeptidases, which are involved in a wide variety of cellular functions. Its catalytic domain displays a high degree of structural homology with those of other m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930e93580f3a295d3680f0fdf62f258f
https://pubmed.ncbi.nlm.nih.gov/23912897
https://pubmed.ncbi.nlm.nih.gov/23912897
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b73bca13dc02811e5aae252055a1d01
https://doi.org/10.1096/fasebj.26.1_supplement.901.4
https://doi.org/10.1096/fasebj.26.1_supplement.901.4