Zobrazeno 1 - 10
of 16
pro vyhledávání: '"George K. Auer"'
Autor:
George K. Auer, Piercen M. Oliver, Manohary Rajendram, Ti-Yu Lin, Qing Yao, Grant J. Jensen, Douglas B. Weibel
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
ABSTRACT Swarmer cells of the Gram-negative uropathogenic bacteria Proteus mirabilis and Vibrio parahaemolyticus become long (>10 to 100 μm) and multinucleate during their growth and motility on polymer surfaces. We demonstrated that the increasing
Externí odkaz:
https://doaj.org/article/e6e11d42cad94fd08e6c6329f9bfb407
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT Cardiolipin (CL) is an anionic phospholipid that plays an important role in regulating protein biochemistry in bacteria and mitochondria. Deleting the CL synthase gene (Δcls) in Rhodobacter sphaeroides depletes CL and decreases cell length
Externí odkaz:
https://doaj.org/article/42441435478f45e39d12141fffc6f0de
Autor:
Rishi R. Trivedi, John A. Crooks, George K. Auer, Joel Pendry, Ilona P. Foik, Albert Siryaporn, Nicholas L. Abbott, Zemer Gitai, Douglas B. Weibel
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT The stiffness of bacteria prevents cells from bursting due to the large osmotic pressure across the cell wall. Many successful antibiotic chemotherapies target elements that alter mechanical properties of bacteria, and yet a global view of t
Externí odkaz:
https://doaj.org/article/b0e1f27012c8493db4b737bc9e32c109
Autor:
Douglas B. Weibel, Fred Chang, Kerwyn Casey Huang, Lillian Zhu, George K. Auer, Amanda Miguel, Pascal D. Odermatt, Julie A. Theriot, Gabriel Billings, Enrique R. Rojas
Publikováno v:
Nature
Gram-negative bacteria possess a complex cell envelope that consists of a plasma membrane, a peptidoglycan cell wall and an outer membrane. The envelope is a selective chemical barrier1 that defines cell shape2 and allows the cell to sustain large me
Autor:
Qing Yao, Manohary Rajendram, Douglas B. Weibel, George K. Auer, Ti-Yu Lin, Grant J. Jensen, Piercen M. Oliver
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
mBio
mBio, Vol 10, Iss 5, p e00210-19 (2019)
mBio
mBio, Vol 10, Iss 5, p e00210-19 (2019)
Proteus mirabilis and Vibrio parahaemolyticus are bacteria that infect humans. To adapt to environmental changes, these bacteria alter their cell morphology and move collectively to access new sources of nutrients in a process referred to as “swarm
Publikováno v:
mBio
mBio, Vol 10, Iss 1 (2019)
mBio, Vol 10, Iss 1, p e02401-18 (2019)
mBio, Vol 10, Iss 1 (2019)
mBio, Vol 10, Iss 1, p e02401-18 (2019)
The phospholipid composition of the cell membrane influences the spatial and temporal biochemistry of cells. We studied molecular mechanisms connecting membrane composition to cell morphology in the model bacterium Rhodobacter sphaeroides. The peptid
Autor:
Ilona P. Foik, George K. Auer, Rishi R. Trivedi, Zemer Gitai, Douglas B. Weibel, Joel Pendry, John A. Crooks, Nicholas L. Abbott, Albert Siryaporn
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
mBio, Vol 9, Iss 5, p e01340-18 (2018)
mBio, vol 9, iss 5
Trivedi, RR; Crooks, JA; Auer, GK; Pendry, J; Foik, IP; Siryaporn, A; et al.(2018). Mechanical Genomic Studies Reveal the Role of d-Alanine Metabolism in Pseudomonas aeruginosa Cell Stiffness.. mBio, 9(5). doi: 10.1128/mBio.01340-18. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8tf287v6
mBio
mBio, Vol 9, Iss 5, p e01340-18 (2018)
mBio, vol 9, iss 5
Trivedi, RR; Crooks, JA; Auer, GK; Pendry, J; Foik, IP; Siryaporn, A; et al.(2018). Mechanical Genomic Studies Reveal the Role of d-Alanine Metabolism in Pseudomonas aeruginosa Cell Stiffness.. mBio, 9(5). doi: 10.1128/mBio.01340-18. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8tf287v6
mBio
A central question in mechanobiology is how cellular-scale structures are established and regulated. In bacteria, the cell envelope is essential for mechanical integrity, protecting against environmental stresses and bearing the load from high turgor
Autor:
Spencer Cesar, Amanda Miguel, George K. Auer, Manohary Rajendram, Timothy K. Lee, Douglas B. Weibel, Kerwyn Casey Huang
Publikováno v:
Cell Systems. 2:402-411
Bacteria must maintain mechanical integrity to withstand the large osmotic pressure differential across the cell membrane and wall. Although maintaining mechanical integrity is critical for proper cellular function, a fact exploited by prominent cell
Autor:
Michael M. Cox, Khanh V. Ngo, Manohary Rajendram, Arun Yethiraj, Douglas B. Weibel, George K. Auer, Bradley J. Reynolds, Hannah H. Tuson, Leili Zhang, Qiang Cui
Publikováno v:
Molecular Cell. 60(3):374-384
We characterize the interaction of RecA with membranes in vivo and in vitro and demonstrate that RecA binds tightly to the anionic phospholipids (aPLs) cardiolipin (CL) and phosphatidylglycerol (PG). Using computational models, we identify two region
Autor:
George K. Auer, Douglas B. Weibel
Cellular mechanical properties play an integral role in bacterial survival and adaptation. Historically, the bacterial cell wall and, in particular, the layer of polymeric material called the peptidoglycan were the elements to which cell mechanics co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2655ed0fffbba2039a638b3f286e064
https://europepmc.org/articles/PMC6260806/
https://europepmc.org/articles/PMC6260806/