Zobrazeno 1 - 10
of 171
pro vyhledávání: '"George J. Schroepfer"'
Autor:
Benfang Ruan, William K. Wilson, Jihai Pang, Nicolas Gerst, Frederick D. Pinkerton, James Tsai, Richard I. Kelley, Frank G. Whitby, Dianna M. Milewicz, James Garbern, George J. Schroepfer, Jr.
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 5, Pp 799-812 (2001)
Smith-Lemli-Opitz syndrome (SLOS) is a hereditary disorder in which a defective gene encoding 7-dehydrocholesterol reductase causes the accumulation of noncholesterol sterols, such as 7- and 8-dehydrocholesterol. Using rigorous analytical methods in
Externí odkaz:
https://doaj.org/article/7f841e5d40b7466db2e839c565d2650b
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 11, Pp 1772-1782 (2000)
Minor aberrant pathways of cholesterol biosynthesis normally produce only trace levels of abnormal sterol metabolites but may assume major importance when an essential biosynthetic step is blocked. Cholesta-5,8-dien-3β-ol, its Δ5,7 isomer, and othe
Externí odkaz:
https://doaj.org/article/ffc54446ec45413e856fe005cedc3171
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 4, Pp 764-772 (1999)
The enantiomeric purity of erythro-sphingosine samples can be determined simply, reliably, and accurately from 1H or 19F nuclear magnetic resonance spectra of the α-methoxy-α-(trifluoromethyl)phenylacetate (MTPA) derivative. As little as 0.1% of th
Externí odkaz:
https://doaj.org/article/b68ba50c7336408d840268ca90129804
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 1, Pp 117-125 (1999)
d-erythro-Sphingosine-1-phosphate (2), an intermediate in sphingosine metabolism, shows a diversity of biological activities. Comparable roles might be anticipated for d-ribo-phytosphingosine-1-phosphate (1). We describe an efficient three-step chemi
Externí odkaz:
https://doaj.org/article/a1c0b5c1ffcb47869a6cce6cf5fc539a
Autor:
Benfang Ruan, Shinya Watanabe, John J. Eppig, Christopher Kwoh, Natasha Dzidic, Jihai Pang, William K. Wilson, George J. Schroepfer, Jr.
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 10, Pp 2005-2020 (1998)
4,4-Dimethyl-5α-cholesta-8,14,24-trien-3β-ol (I) from human follicular fluid and 4,4-dimethyl-5α-cholesta-8,24-dien-3β-ol (II) from bull testes have been reported to activate meiosis in mouse oocytes (Byskov et al., 1995. Nature. 374: 559–562).
Externí odkaz:
https://doaj.org/article/6e1289a21e394d7890b29866ce405844
Publikováno v:
Journal of Lipid Research, Vol 4, Iss 3, Pp 266-269 (1963)
Chromatographic separations of dimethyl allyl alcohol, geraniol, nerol, nerolidol, and trans-trans-farnesol were achieved on silicic acid-Super Cel columns. Application of this chromatographic system to the radioactive nonsaponifiable lipids formed f
Externí odkaz:
https://doaj.org/article/6f02abf589b743518050f20b59640f73
Publikováno v:
Molecular Structure and Biological Activity of Steroids ISBN: 9781351074803
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a691c5472a947229e5bb525176002c14
https://doi.org/10.1201/9781351074803-2
https://doi.org/10.1201/9781351074803-2
Publikováno v:
Steroids. 68:221-233
Oxygenated derivatives of cholesterol have important functions in many biochemical processes. These oxysterols are difficult to study because of their low physiological concentrations, the facile formation of cholesterol autoxidation artifacts, and l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29daf6875e1f9db6f7bb8386d7822618
https://doi.org/10.1016/s0039-128x(02)00185-x
https://doi.org/10.1016/s0039-128x(02)00185-x
Autor:
Ran Xu, Benfang Ruan, George J. Schroepfer, Christine W Yeh, Seiichi P. T. Matsuda, Jihai Pang, William K. Wilson, Peggy S Lai
Publikováno v:
Steroids. 67:1109-1119
Yeast produce traces of aberrant sterols by minor alternative pathways, which can become significant when normal metabolism is blocked by inhibitors or mutations. We studied sterols generated in the absence of the delta(8)-delta(7) isomerase (Erg2p)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf9b9b0aca098bf9a681b31187b09913
https://doi.org/10.1016/s0039-128x(02)00069-7
https://doi.org/10.1016/s0039-128x(02)00069-7
Autor:
George J. Schroepfer, Nicolas Gerst, William K. Wilson, Frederick D. Pinkerton, Dianna M. Milewicz, Richard I. Kelley, Frank G. Whitby, James Y. Garbern, James Tsai, Benfang Ruan, Jihai Pang
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 5, Pp 799-812 (2001)
Smith-Lemli-Opitz syndrome (SLOS) is a hereditary disorder in which a defective gene encoding 7-dehydrocholesterol reductase causes the accumulation of noncholesterol sterols, such as 7- and 8-dehydrocholesterol. Using rigorous analytical methods in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a479170c0e78f85be443ec70776fb4
https://doi.org/10.1016/s0022-2275(20)31643-6
https://doi.org/10.1016/s0022-2275(20)31643-6