Zobrazeno 1 - 10
of 10
pro vyhledávání: '"George J. Quellhorst"'
Autor:
Xiujing Gu, Song Tian, Young Woo Kim, George J. Quellhorst, Scott F. Winter, Jixin Deng, Frank Reinecke, Eric Lader, Raghavendra Padmanabhan, Dan Heard, Raed Samara, James Keller, John DiCarlo, Hong Xu, Mohammad R. Nezami Ranjbar
Publikováno v:
Cancer Research. 80:753-753
With the adoption of NGS as a powerful tool for molecular biology research, researchers seek to efficiently utilize genetic variation information for cancer identification which otherwise would be difficult with traditional method. For example, targe
Autor:
Jessica L. O'Rear, Sharon S. Krag, George J. Quellhorst, Paul T. Englund, Soo Hee Lee, Alvaro Acosta-Serrano, Kuo-Yuan Hwa
Publikováno v:
Eukaryotic Cell. 3:255-263
Concanavalin A (ConA) kills the procyclic (insect) form of Trypanosoma brucei by binding to its major surface glycoprotein, procyclin. We previously isolated a mutant cell line, ConA 1-1, that is less agglutinated and more resistant to ConA killing t
Publikováno v:
Wiley Encyclopedia of Molecular Medicine.
Publikováno v:
The Journal of biological chemistry. 276(44)
A photoprobe analog of geranylgeranyl diphosphate (2-diazo-3,3,3-trifluoropropionyloxy-farnesyl diphosphate or DATFP-FPP) inhibits mevalonate-dependent prenylation of in vitro translated Rab5 in rabbit reticulocyte lysate, suggesting that it competes
Publikováno v:
Glycobiology. 9(1)
A CHO mutant MI8-5 was found to synthesize Man9-GlcNAc2-P-P-dolichol rather than Glc3Man9GlcNAc2-P-P-dolichol as the oligosaccharide-lipid intermediate in N-glycosylation of proteins. MI8-5 cells were incubated with labeled mevalonate, and the prenol
Publikováno v:
Archives of biochemistry and biophysics. 343(1)
CHB11-1-3 is a glycosylation mutant of Chinese hamster ovary (CHO) cells, isolated by screening mutagenized cells for those with decreased intracellular lysosomal enzyme activity [C. W. Hall et al. (1986) Mol. Cell. Biochem. 72, 35–45]. CHB11-1-3 s
Autor:
Jiaye Yu, Michael J. Crowley, George J. Quellhorst, Raymond K. Blanchard, John DiCarlo, Vikram Devgan, Nadejda Slepushkina, Thomas J. Fahey, Song Tian, Xiao Zeng
Publikováno v:
Journal of Clinical Oncology. 30:e21011-e21011
e21011 Background: Thyroid nodules can be detected in as high as 67% of the population. Distinguishing thyroid cancers from benign lesions is crucial for determining an appropriate treatment plan. For years a gene expression signature for discriminat
Autor:
Xiujing Gu, George J. Quellhorst, Kathy Boon, Yuye Lin, Rui Han, Jonathan M. Shaffer, Yan Xiang, Chun-Xiang Liu, Guozhen Liu
Publikováno v:
Cancer Research. 70:149-149
Histone modifications and DNA methylation are epigenetic events that can modulate gene expression patterns associated with normal development and disease pathology. Epigenetic alterations are clearly involved in breast cancer initiation and progressi
Publikováno v:
Cancer Research. 70:LB-140
Objectives: Histone modification marks and gene expression profiling on multiple human oncogenes and tumor suppressor genes to study the correlation between epigenetic modifications and gene expression in cancer cells derived from different tissue/ce
Autor:
Ligaba, Segni B.1, Khurana, Anikita1, Graham, Garrett2, Krawczyk, Ewa1, Jablonski, Sandra2,3, Petricoin, Emanuel F.4, Glazer, Robert I.2,3, Upadhyay, Geeta1,2,3 gu6@georgetown.edu
Publikováno v:
PLoS ONE. Feb2015, Vol. 10 Issue 2, p1-11. 11p.