Výsledky vyhledávání - "George J. L. Lee"

Enhancement of Solubility, Dissolution Rate, and Oral Bioavailability of Rs-82856 by Complex Formation with Cyclodextrins

Autor: Ian J. Massey, George J. L. Lee, Cheng Der Yu, Stephanie A. Sweetana, Nancy Chu

Publikováno v: Drug Development and Industrial Pharmacy. 15:609-620

RS-82856 is a new inotropic agent for treatment of congestive heart failure. Oral bioavailability was found to be very poor likely due to insufficient aqueous solubility (∼ 4.4 mcg/ml) and slow dissolution rate. Inclusion complexes with cyclodextri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f8af7cb7e6d5086d4205e5f8386fb71
https://doi.org/10.3109/03639048909040233

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