Zobrazeno 1 - 10
of 99
pro vyhledávání: '"George J. Giudice"'
Autor:
Kelly A.N. Messingham, George J. Giudice, Elizabeth M. Vanderah, Amber Onoh, Janet A. Fairley
Publikováno v:
Hybridoma. 31:111-117
BP180 (collagen XVII) is the target antigen in several autoimmune diseases including bullous pemphigoid (BP). Both IgE and IgG class autoantibodies have been shown to be pathogenic in BP; however, studies designed to elucidate the patho-mechanisms me
Publikováno v:
Journal of Immunological Methods. 346:18-25
Bullous pemphigoid (BP) is a humoral autoimmune disease directed predominantly against the non-collagenous NC16A domain of the BP180 hemidesmosomal protein. Our laboratory has recently shown, using a mouse xenograft model, that passive transfer of Ig
Autor:
Randy J. Thresher, Zhi Liu, George J. Giudice, Gang Ning, Wen Sui, Minglang Zhao, Zhuowei Li, Ning Li, Cassian Sitaru, Detlef Zillikens, Luis A. Diaz, Janet A. Fairley, M. Peter Marinkovich
Publikováno v:
Journal of Autoimmunity. 31:331-338
Bullous pemphigoid (BP) is a cutaneous autoimmune inflammatory disease associated with subepidermal blistering and autoantibodies against BP180, a transmembrane collagen and major component of the hemidesmosome. Numerous inflammatory cells infiltrate
Publikováno v:
Journal of Investigative Dermatology. 125(3):467-472
Bullous pemphigoid (BP) is a subepidermal blistering disease characterized by autoantibodies against the hemidesmosomal protein BP180 (BPAg2, type XVII collagen). NC16A, a non-collagenous stretch of the BP180 ectodomain, is the primary target of path
Publikováno v:
Journal of the American Academy of Dermatology. 51:118-122
Bullous pemphigoid (BP) and epidermolysis bullosa acquisita are distinct autoimmune blistering disorders. BP is characterized by autoantibodies directed against the NC16A domain of collagen XVII, whereas patients with epidermolysis bullosa acquisita
Autor:
Francoise Van den Bergh, Otobia G. Dimson, Marleen M. Janson, Simon Warren, George J. Giudice, Chang Ling Fu, Janet A. Fairley
Publikováno v:
Journal of Investigative Dermatology. 120:784-788
Bullous pemphigoid (BP) is an autoimmune skin disease characterized by autoantibodies against the hemidesmosomal protein BP180. In addition to IgG autoantibodies, IgE class autoantibodies have been reported in BP patients. Because animal models utili
Autor:
Ming Lang Zhao, Ruoyan Chen, Zhi Liu, George J. Giudice, Janet A. Fairley, Detlef Zillikens, Luis A. Diaz
Publikováno v:
The Journal of Immunology. 169:3987-3992
Bullous pemphigoid (BP) is a subepidermal blistering disease associated with autoantibodies against two hemidesmosomal proteins, BP180 and BP230. Numerous inflammatory cells infiltrate the upper dermis in BP. We have previously shown by passive trans
Autor:
Janet A. Fairley, Detlef Zillikens, Monica Olague-Marchan, Chang-Ling Fu, George J. Giudice, Mary K. Hacker, Mong-Shang Lin
Publikováno v:
Clinical Immunology. 102:310-319
Linear IgA bullous disease (LABD) is an autoimmune skin disease characterized by subepidermal blisters and IgA autoantibodies directed against the epidermal basement membrane zone (BMZ) of the skin. Various antigens have been identified as targets of
Autor:
Raymond G. Hoffmann, Luis A. Diaz, Simon Warren, Mong Shang Lin, Evandro A. Rivitti, George J. Giudice, Gunter Hans-Filho, Vandir dos Santos, Valeria Aoki
Publikováno v:
New England Journal of Medicine. 343:23-30
Background Pemphigus foliaceus is an autoimmune skin disease mediated by autoantibodies against desmoglein 1. The endemic form is thought to have an environmental cause. The Terena reservation of Limao Verde in Mato Grosso do Sul, Brazil, is a recent
Autor:
Sally S. Twining, Mary K. Hacker, George J. Giudice, Monica Olague-Marchan, Luis A. Diaz, John A. McGrath
Publikováno v:
Matrix Biology. 19:223-233
BP180 is a homotrimeric transmembrane protein with a carboxy-terminal ectodomain that forms an interrupted collagen triple helix. Null type mutations in the BP180 gene produce a recessive subepidermal blistering disease, non-Herlitz junctional epider