Zobrazeno 1 - 3
of 3
pro vyhledávání: '"George J. Delinassios"'
Autor:
Vincent Kao, David M. Davies, May C I van Schalkwyk, Sjoukje J. C. van der Stegen, Zhe Liu, Ana C. Parente-Pereira, Laura Chiapero-Stanke, Carol Box, Sophie Burbridge, George J. Delinassios, Leticia Bosshard-Carter, Suzanne A. Eccles, Julie Foster, John Maher, Scott Wilkie, Stephen J. Mather
Publikováno v:
Molecular Medicine. 18:565-576
Pharmacological targeting of individual ErbB receptors elicits antitumor activity, but is frequently compromised by resistance leading to therapeutic failure. Here, we describe an immunotherapeutic approach that exploits prevalent and fundamental mec
Autor:
Mahsa Karbaschi, George J. Delinassios, Antony R. Young, Hussein H. K. Abbas, Mark D. Evans, Vilas Mistry, Marcus S. Cooke, Salvador Macip
Classically, the nucleotide excision repair (NER) of cyclobutane pyrimidine dimers (CPD) is a lengthy process (t1/2 > 48 h). Using the T4 endonuclease V-modified comet assay, we uniquely found a far more rapid repair of UVA-induced CPD (t1/2 = 4.5 h)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc35be9260889f33117120b22341a3e
http://hdl.handle.net/2086/12511
http://hdl.handle.net/2086/12511
Autor:
Sophie Burbridge, George J. Delinassios, Scott Wilkie, David M. Davies, Suzanne A. Eccles, Stephen J. Mather, Julie Foster, John Maher, Laura Chiapero-Stanke
Publikováno v:
Cancer Research. 70:1932-1932
Over-expression of the epidermal growth factor receptor (ErbB1) is found in the majority of squamous cell carcinomas of the head and neck (SCCHN), making it an attractive therapeutic target. However, tumors often become refractory to ErbB1-specific t