Zobrazeno 1 - 10
of 54
pro vyhledávání: '"George J Dugbartey"'
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136113 (2015)
Therapeutic hypothermia is used to reduce ischemia/reperfusion injury (IRI) during organ transplantation and major surgery, but does not fully prevent organ injury. Interestingly, hibernating animals undergo repetitive periods of low body temperature
Externí odkaz:
https://doaj.org/article/99242379d7e74b7db64faf26f5f802a0
Autor:
Edwin L de Vrij, Pieter C Vogelaar, Maaike Goris, Martin C Houwertjes, Annika Herwig, George J Dugbartey, Ate S Boerema, Arjen M Strijkstra, Hjalmar R Bouma, Robert H Henning
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93218 (2014)
Hibernation is an energy-conserving behavior in winter characterized by two phases: torpor and arousal. During torpor, markedly reduced metabolic activity results in inactivity and decreased body temperature. Arousal periods intersperse the torpor bo
Externí odkaz:
https://doaj.org/article/cc1ecf24042f48cba800b5264bc6dab0
Autor:
Sydney Relouw, George J. Dugbartey, Patrick McLeod, Natasha N. Knier, Francisco Martinez Santiesteban, Paula J. Foster, Heather-Anne Cadieux-Pitre, Nicole M. Hague, Jenna Caine, Kaitlin Belletti, Sally Major, Caroline O’Neil, Manal Y. Gabril, Madeleine Moussa, Melissa J. Huynh, S.M. Mansour Haeryfar, Alp Sener
Publikováno v:
Pharmaceuticals, Vol 17, Iss 9, p 1212 (2024)
Present bladder cancer therapies have relatively limited therapeutic impact and account for one of the highest lifetime treatment costs per patient. Therefore, there is an urgent need to explore novel and optimized treatment strategies. The present s
Externí odkaz:
https://doaj.org/article/cdbebf895e8a4a71b61116e9361ba8c3
Autor:
George J. Dugbartey, Karl K. Alornyo, Christabel O. Dapaa-Addo, Emmanuel Botchway, Emmanuel K. Kwashie, Yvonne Harley
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 7, Iss , Pp 100206- (2024)
Kidney diseases have rapidly increased in prevalence over the past few decades, and have now become a major global public health concern. This has put economic burden on the public healthcare system and causing significant morbidity and mortality wor
Externí odkaz:
https://doaj.org/article/dfd2f3736ced444da47fe4c315815576
Autor:
George J. Dugbartey, Karl K. Alornyo, Ismaila Adams, Stephen Atule, Richard Obeng-Kyeremeh, Daniel Amoah, Samuel Adjei
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 14, Iss 1, Pp 1-17 (2022)
Abstract Background Diabetes-induced liver injury is a complication of diabetes mellitus of which there are no approved drugs for effective treatment or prevention. This study investigates possible hepatoprotective effect of alpha-lipoic acid (ALA),
Externí odkaz:
https://doaj.org/article/b6e07eccbd6640d4b7a6ff319bf1770a
Publikováno v:
Antioxidants, Vol 13, Iss 3, p 287 (2024)
Bladder cancer (BCa) is the most common genitourinary malignancy, with a high global incidence and recurrence rate that is paired with an increasing caregiver burden and higher financial cost, in addition to increasing morbidity and mortality worldwi
Externí odkaz:
https://doaj.org/article/ee784e8dca0842d788ed6e1bf7ff20a1
Autor:
Kennedy K.E. Kukuia, Frimpong Appiah, George J. Dugbartey, Yaw F. Takyi, Patrick Amoateng, Seth K. Amponsah, Ofosua Adi-Dako, Awo E. Koomson, Frederick Ayertey, Kevin K. Adutwum-Ofosu
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background/Aim: Depression-related aggression is linked to serotonin (5-HT) and dendritic spine alterations. Although Mallotus oppositifolius extract (MOE) has potential for reducing this effect, its specific role remains uncertain. Herein, we evalua
Externí odkaz:
https://doaj.org/article/0ef723921f1748b4b0c73d3e540bcd47
Autor:
George J. Dugbartey, Quinsker L. Wonje, Karl K. Alornyo, Louis Robertson, Ismaila Adams, Vincent Boima, Samuel D. Mensah
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Diabetic cardiomyopathy (DCM) is a major long-term complication of diabetes mellitus, accounting for over 20% of annual mortality rate of diabetic patients globally. Although several existing anti-diabetic drugs have improved glycemic sta
Externí odkaz:
https://doaj.org/article/a1362a4d62b347e6ba42917ab1724264
Autor:
George J. Dugbartey
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Pancreatic islet transplantation is a minimally invasive procedure to replace β-cells in a subset of patients with autoimmune type 1 diabetic mellitus, who are extremely sensitive to insulin and lack counter-regulatory measures, and thereby increasi
Externí odkaz:
https://doaj.org/article/7d16a296eaf444a1b82aeb32b5d71259
Autor:
Vyacheslav A. Korshunov, Elaine M. Smolock, Mary E. Wines‐Samuelson, Abrar Faiyaz, Deanne M. Mickelsen, Breandan Quinn, Calvin Pan, George J. Dugbartey, Chen Yan, Marvin M. Doyley, Aldons J. Lusis, Bradford C. Berk
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 10 (2020)
Background Carotid artery intima/media thickness (IMT) is a hallmark trait associated with future cardiovascular events. The goal of this study was to map new genes that regulate carotid IMT by genome‐wide association. Methods and Results We induce
Externí odkaz:
https://doaj.org/article/26da8cbb24ac4d5c835b7e9142e7bc5a