Zobrazeno 1 - 10
of 372
pro vyhledávání: '"George J Bosl"'
Autor:
Paul B Chapman, Nathan J Liu, Qin Zhou, Alexia Iasonos, Sara Hanley, George J Bosl, David R Spriggs
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184025 (2017)
Very little is known about the proportion of oncology trials that get published, the time it takes to publish them, or the reasons why oncology trials do not get published.We analyzed all clinical trials that closed to accrual at our cancer center be
Externí odkaz:
https://doaj.org/article/d3f2222b62674e2480503bc91d1e4eee
Autor:
James E Korkola, Sandy Heck, Adam B Olshen, Darren R Feldman, Victor E Reuter, Jane Houldsworth, George J Bosl, R S K Chaganti
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0142846 (2015)
Germ Cell Tumors (GCT) have a high cure rate, but we currently lack the ability to accurately identify the small subset of patients who will die from their disease. We used a combined genomic and expression profiling approach to identify genomic regi
Externí odkaz:
https://doaj.org/article/12cc09e6abed473e89953e6de7cf0eae
Autor:
Francesca Cavallo, Grazia Graziani, Cristina Antinozzi, Darren R Feldman, Jane Houldsworth, George J Bosl, Raju S K Chaganti, Mary Ellen Moynahan, Maria Jasin, Marco Barchi
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51563 (2012)
Testicular Germ Cell Tumors (TGCT) and patient-derived cell lines are extremely sensitive to cisplatin and other interstrand cross-link (ICL) inducing agents. Nevertheless, a subset of TGCTs are either innately resistant or acquire resistance to cisp
Externí odkaz:
https://doaj.org/article/8852e1fae75d40eaa546364ea4f27085
Autor:
R.S.K. Chaganti, George J. Bosl, Victor E. Reuter, Debbie Dobrzynski, Adam B. Olshen, Rajendrakumar S.V. Chadalavada, Jane Houldsworth, James E. Korkola
Adult male germ cell tumors (GCTs) comprise distinct groups: seminomas and nonseminomas, which include pluripotent embryonal carcinomas as well as other histologic subtypes exhibiting various stages of differentiation. Almost all GCTs show 12p gain,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b09545c4cb3be9d277649a80b757239
https://doi.org/10.1158/0008-5472.c.6494178.v1
https://doi.org/10.1158/0008-5472.c.6494178.v1
Autor:
R.S.K. Chaganti, George J. Bosl, Victor E. Reuter, Debbie Dobrzynski, Adam B. Olshen, Rajendrakumar S.V. Chadalavada, Jane Houldsworth, James E. Korkola
Supplementary Figures 1-4 from Down-Regulation of Stem Cell Genes, Including Those in a 200-kb Gene Cluster at 12p13.31, Is Associated with In vivo Differentiation of Human Male Germ Cell Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a89462c2a59df47256dd088ae2b9f3
https://doi.org/10.1158/0008-5472.22364412
https://doi.org/10.1158/0008-5472.22364412
Autor:
R.S.K. Chaganti, George J. Bosl, Victor E. Reuter, Debbie Dobrzynski, Adam B. Olshen, Rajendrakumar S.V. Chadalavada, Jane Houldsworth, James E. Korkola
Supplementary Table 1-5 from Down-Regulation of Stem Cell Genes, Including Those in a 200-kb Gene Cluster at 12p13.31, Is Associated with In vivo Differentiation of Human Male Germ Cell Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e005248346f78ea38ca7b7c18af9f00f
https://doi.org/10.1158/0008-5472.22364406.v1
https://doi.org/10.1158/0008-5472.22364406.v1
Autor:
Ritu Kushwaha, Nirmala Jagadish, Manjunath Kustagi, Geetu Mendiratta, Marco Seandel, Rekha Soni, James E. Korkola, Venkata Thodima, Andrea Califano, George J. Bosl, R.S.K. Chaganti
Publikováno v:
Stem Cell Reports, Vol 6, Iss 5, Pp 772-783 (2016)
Human male germ cell tumors (GCTs) are derived from primordial germ cells (PGCs). The master pluripotency regulator and neuroectodermal lineage effector transcription factor SOX2 is repressed in PGCs and the seminoma (SEM) subset of GCTs. The mechani
Externí odkaz:
https://doaj.org/article/bd88eb4968734926974e7858d2b5c5a4
Autor:
George J. Bosl, Gaetano Rocco, Manjit S. Bains, David R. Jones, Samuel Funt, Daniela Molena, Raul Caso, David Amar, Darren R. Feldman, Joel Sheinfeld, Victor E. Reuter, Gregory W. Fischer, Gregory D. Jones, Kay See Tan
Publikováno v:
Ann Thorac Surg
BACKGROUND Outcomes after thoracic metastasectomy in patients with testicular germ cell tumors (GCTs) who received first-line chemotherapy alone versus salvage chemotherapy remain unexplored. METHODS We conducted a retrospective review of patients wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434384e15677fca8f6839e59b8218a19
https://doi.org/10.1016/j.athoracsur.2020.06.072
https://doi.org/10.1016/j.athoracsur.2020.06.072
Autor:
Gregory W. Fischer, Kay See Tan, Darren R. Feldman, Meier Hsu, Manjit S. Bains, George J. Bosl, Gregory D. Jones, James Huang, David R. Jones, Victor E. Reuter, Samuel Funt, David Amar, Daniela Molena, Deaglan Joseph McHugh, Valerie W. Rusch, Raul Caso
Publikováno v:
Ann Surg
OBJECTIVE: We examined management strategies, overall survival (OS), and progression-free survival (PFS) among patients with primary mediastinal nonseminomatous germ cell tumors (PMNSGCTs) undergoing resection and multidisciplinary management at a hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f44e2aa72d7352a136ca4322edfa4c1
https://doi.org/10.1097/sla.0000000000003754
https://doi.org/10.1097/sla.0000000000003754
Autor:
Darren R. Feldman, Robert J. Motzer, George J. Bosl, Andrew Feifer, Mariam Imnadze Miller, Joel Sheinfeld, Brett S. Carver, Dean F. Bajorin
Publikováno v:
Urology. 124:174-178
Objective To characterize clinical and pathologic outcomes of cisplatin-refractory or relapsed germ cell tumor (GCT) patients who underwent retroperitoneal lymph node dissection (RPLND) following salvage chemotherapy with either conventional or high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de61ae2613592fa4e3b8127f2971c58
https://doi.org/10.1016/j.urology.2018.09.024
https://doi.org/10.1016/j.urology.2018.09.024