Zobrazeno 1 - 10
of 633
pro vyhledávání: '"George J, Netto"'
Autor:
Darshan Shimoga Chandrashekar, Santhosh Kumar Karthikeyan, Praveen Kumar Korla, Henalben Patel, Ahmedur Rahman Shovon, Mohammad Athar, George J. Netto, Zhaohui S. Qin, Sidharth Kumar, Upender Manne, Chad J. Crieghton, Sooryanarayana Varambally
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 25, Iss , Pp 18-27 (2022)
Cancer genomic, transcriptomic, and proteomic profiling has generated extensive data that necessitate the development of tools for its analysis and dissemination. We developed UALCAN to provide a portal for easy exploring, analyzing, and visualizing
Externí odkaz:
https://doaj.org/article/1a9e0242ef414e7eaa55cb8ccec24f42
Autor:
Hasibur Rehman, Darshan S. Chandrashekar, Chakravarthi Balabhadrapatruni, Saroj Nepal, Sai Akshaya Hodigere Balasubramanya, Abigail K. Shelton, Kasey R. Skinner, Ai-Hong Ma, Ting Rao, Sumit Agarwal, Marie-Lisa Eich, Alyncia D. Robinson, Gurudatta Naik, Upender Manne, George J. Netto, C. Ryan Miller, Chong-xian Pan, Guru Sonpavde, Sooryanarayana Varambally, James E. Ferguson III
Publikováno v:
JCI Insight, Vol 7, Iss 16 (2022)
Metastatic urothelial carcinoma is generally incurable with current systemic therapies. Chromatin modifiers are frequently mutated in bladder cancer, with ARID1A-inactivating mutations present in about 20% of tumors. EZH2, a histone methyltransferase
Externí odkaz:
https://doaj.org/article/8e79799b8d1942819fca44a09858150e
Autor:
Enrico Munari, Giulia Querzoli, Matteo Brunelli, Marcella Marconi, Marco Sommaggio, Marco A. Cocchi, Guido Martignoni, George J. Netto, Anna Caliò, Linda Quatrini, Francesca R. Mariotti, Claudio Luchini, Ilaria Girolami, Albino Eccher, Diego Segala, Francesco Ciompi, Giuseppe Zamboni, Lorenzo Moretta, Giuseppe Bogina
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Different programmed cell death-ligand 1 (PD-L1) assays and scoring algorithms are being used in the evaluation of PD-L1 expression for the selection of patients for immunotherapy in specific settings of advanced urothelial carcinoma (UC). In this pa
Externí odkaz:
https://doaj.org/article/00d6198449924517bf4712476032448f
Autor:
George J Netto, Chandrakumar Shanmugam, Michael Behring, Vishwas Luthra, Sixto M Leal, Sooryanarayana Varambally, Upender Manne
Publikováno v:
BMJ Open, Vol 12, Iss 4 (2022)
Background Accurate detection of SARS-CoV-2 is necessary to mitigate the COVID-19 pandemic. However, the test reagents and assay platforms are varied and may not be sufficiently robust to diagnose COVID-19.Methods We reviewed 85 studies (21 530 patie
Externí odkaz:
https://doaj.org/article/823a7200410f41fcb7169bf1a22fd208
Autor:
Marie-Lisa Eich, Maria Del Carmen Rodriguez Pena, Darshan Shimoga Chandrashekar, Alcides Chaux, Sumit Agarwal, Jennifer B. Gordetsky, James E. Ferguson, Guru P. Sonpavde, George J. Netto, Sooryanarayana Varambally
Publikováno v:
Translational Oncology, Vol 12, Iss 11, Pp 1416-1424 (2019)
Cancer cells utilize vitamin folate to fulfill their excessive demand for nucleotides and amino acids. Dihydrofolate reductase (DHFR), an enzyme involved in folate metabolism converts dihydrofolate into tetrahydrofolate, which is required for the de
Externí odkaz:
https://doaj.org/article/b393174b479b45e794681d6ef1c8f1fc
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Urothelial carcinoma (UC) is a common urological malignancy with a high rate of disease recurrence. Telomerase activity, a hallmark of cancer characterized by overcoming the replicative senescence, is upregulated in over 90% of patients with UC. Soma
Externí odkaz:
https://doaj.org/article/5dda4ab842f043cd90ef4d434873c949
Autor:
Enrico Munari, Marcella Marconi, Giulia Querzoli, Gianluigi Lunardi, Pietro Bertoglio, Francesco Ciompi, Alice Tosadori, Albino Eccher, Nicola Tumino, Linda Quatrini, Paola Vacca, Giulio Rossi, Alberto Cavazza, Guido Martignoni, Matteo Brunelli, George J. Netto, Lorenzo Moretta, Giuseppe Zamboni, Giuseppe Bogina
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The immune infiltrate within tumors has proved to be very powerful in the prognostic stratification of patients and much attention is also being paid towards its predictive value. In this work we therefore aimed at clarifying the significance and imp
Externí odkaz:
https://doaj.org/article/38fce130e5484fd6927b40f8831e269c
Autor:
Satoshi Inoue, Taichi Mizushima, Hiroki Ide, Guiyang Jiang, Takuro Goto, Yujiro Nagata, George J Netto, Hiroshi Miyamoto
Publikováno v:
Endocrine Connections, Vol 7, Iss 12, Pp 1397-1408 (2018)
We investigated the functional role of ATF2, a transcription factor normally activated via its phosphorylation in response to phospho-ERK/MAPK signals, in the outgrowth of urothelial cancer. In both neoplastic and non-neoplastic urothelial cells, the
Externí odkaz:
https://doaj.org/article/cecb66f276b44ab0a051ad6c0c21e96a
Autor:
Santhosh Kumar Karthikeyan, Nuo Xu, James E. Ferguson 3, Soroush Rais‐Bahrami, Zhaohui S. Qin, Upender Manne, George J. Netto, Darshan S. Chandrashekar, Sooryanarayana Varambally
Publikováno v:
The Prostate. 83:590-601
Autor:
Yujiro Hayashi, Kazutoshi Fujita, Kyosuke Matsuzaki, Marie-Lisa Eich, Eisuke Tomiyama, Makoto Matsushita, Yoko Koh, Kosuke Nakano, Cong Wang, Yu Ishizuya, Taigo Kato, Koji Hatano, Atsunari Kawashima, Takeshi Ujike, Motohide Uemura, Ryoichi Imamura, George J. Netto, Norio Nonomura
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Recent studies showed the clinical utility of next-generation sequencing of urinary cell-free DNA (cfDNA) from patients with urothelial bladder cancer (UBC). In this study, we aimed to develop urinary cfDNA analysis by droplet digital PCR (ddPCR) as
Externí odkaz:
https://doaj.org/article/1dccd974f7014f8996888db2fa8234bf