Zobrazeno 1 - 10
of 65
pro vyhledávání: '"George I. Drummond"'
Autor:
George I. Drummond
Publikováno v:
Archives of Biochemistry and Biophysics. 211:30-38
Cardiac adenylate cyclase whether membrane-bound or soluble underwent rapid oxidation in the absence of thiol; loss of activity was reversed by dithiothreitol and several monothiols. The enzyme was also inactivated by hydrogen peroxide; in this case
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5480345d00bd0cd7ad9a86d5761bd28a
https://doi.org/10.1016/0003-9861(81)90425-2
https://doi.org/10.1016/0003-9861(81)90425-2
Autor:
George I. Drummond, N.C. Morcos
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 598:27-39
An enriched fraction of plasma membranes was prepared from canine ventricle by a process which involved thorough disruption of membranes by vigorous homogenization in dilute suspension, sedimentation of contractile proteins and mitochondria at 3000 X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2093fd7c11047b9aff16c60b8a3b49
https://doi.org/10.1016/0005-2736(80)90263-1
https://doi.org/10.1016/0005-2736(80)90263-1
Publikováno v:
Biochemistry. 14:669-675
3',5'-CAMP phosphodiesterase was partially purified from bovine cerebral cortex. A heat-stable activating factor was separated from the enzyme by chromatography on DEAE-cellulose. The enzyme in crude ammonium sulfate fractions was stimulated by 5 mM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7145c64a8c045e940f742eeabbf9d74f
https://doi.org/10.1021/bi00675a004
https://doi.org/10.1021/bi00675a004
Publikováno v:
Life Sciences. 15:319-328
Dibutyryl cyclic AMP when administered to perfused rat hearts produced increased contractile tension and increased intracellular levels of cyclic AMP. When [ 3 H]dibutyryl cyclic AMP was administered, it was taken up by the heart in extremely small a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162f8b96358357fa7fb95895993d77a8
https://doi.org/10.1016/0024-3205(74)90222-7
https://doi.org/10.1016/0024-3205(74)90222-7
Autor:
Minta Huang, George I. Drummond
Publikováno v:
Biochemical Pharmacology. 25:2713-2719
Adenosine stimulated cyclic AMP accumulation in guinea pig ventricular slice preparations. The response to adenosine was dose-dependent over the range 0.1 to 100 μM; half-maximal stimulation occurred at 25 μM. The response to the nucleoside was rap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6459c61a71138b97e5206a9c78bd734
https://doi.org/10.1016/0006-2952(76)90262-8
https://doi.org/10.1016/0006-2952(76)90262-8
Autor:
George I. Drummond, Floyd F. Snyder
Publikováno v:
Archives of Biochemistry and Biophysics. 185:116-125
The rate of cyclic AMP formation by rabbit heart membrane particles decreased at assay temperatures greater than 30 °C. Adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] activity (assayed at 24 °C) decreased exponentially with tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895cd2f235d512cc1c70498c3e617bd5
https://doi.org/10.1016/0003-9861(78)90150-9
https://doi.org/10.1016/0003-9861(78)90150-9
Autor:
Samuel Weiss, George I. Drummond
Publikováno v:
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry. 80:251-255
1. 1. Several biochemical properties of adenylate cyclase were examined in particulate and detergent-solubilized preparations of gill tissue in Aplysia californica. 2. 2. Enzyme activity in a 38,000 g particulate fraction was stimulated 250-fold by N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddd5d2ac7a4c0629d7dfb3f5ab67abf1
https://doi.org/10.1016/0305-0491(85)90205-6
https://doi.org/10.1016/0305-0491(85)90205-6
Autor:
George I. Drummond, Mamoru Sano
Publikováno v:
Journal of Neurochemistry. 37:558-566
Adenylate cyclase was solubilized from washed particulate fraction of rabbit cerebral cortex with the nonionic detergent Lubrol 12A9 and subjected to either gel filtration on Ultrogel AcA 34 or chromatography on DEAE Bio-Gel A. By both procedures the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92e5b4f4f854915b090fe0f26c2809f
https://doi.org/10.1111/j.1471-4159.1982.tb12523.x
https://doi.org/10.1111/j.1471-4159.1982.tb12523.x
Autor:
George I. Drummond
Publikováno v:
Journal of Molecular and Cellular Cardiology. 17:183-194
The catalytic unit (C) of cardiac adenylate cyclase was resolved from the guanine nucleotide-binding regulatory protein (G/F) by fractionation of Lubrol 12A9 extracts with 33% saturated (NH 4 ) 2 SO 4 and by gel filtration in the presence of 3-[(3-ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d0ab12e137c2223c199c89a3136286
https://doi.org/10.1016/s0022-2828(85)80020-1
https://doi.org/10.1016/s0022-2828(85)80020-1
Autor:
George I. Drummond, Jean Dunham
Publikováno v:
Archives of Biochemistry and Biophysics. 189:63-75
Adenylate cyclase from rabbit ventricle was solubilized in 30 to 50% yield by the nonionic detergent Lubrol PX. The detergent, when present in the assay at concentrations above 0.05%, rapidly inactivated the enzyme in assays conducted above 26 °C; a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d473a41e3cecaa74cd4e2bdffecd91ab
https://doi.org/10.1016/0003-9861(78)90114-5
https://doi.org/10.1016/0003-9861(78)90114-5