Altered Interleukin-10 Signaling in Skeletal Muscle Regulates Obesity-Mediated Inflammation and Insulin Resistance

Autor: Werner Müller, George H. Tsougranis, Sezin Dagdeviren, Duy A. Tran, Jason K. Kim, Nicholas Tsitsilianos, Hye Lim Noh, Jung Yeon Kwon, Cecilia P. Uong, Dae Young Jung, Ki Won Lee, Andrew V. Tsitsilianos, Eun-Jung Lee, Payal R. Patel, Caitlyn C. Kearns, Randall H. Friedline, Jong Hun Kim

Publikováno v: Dagdeviren, S, Jung, D Y, Lee, E, Friedline, R H, Noh, H-L, Kim, J H, Patel, P R, Tsitsilianos, N, Tsitsilianos, A V, Tran, D A, Tsougranis, G H, Kearns, C C, Uong, C P, Kwon, J Y, Muller, W, Lee, K W & Kim, J K 2016, ' Altered Interleukin-10 Signaling in Skeletal Muscle Regulates Obesity-Mediated Inflammation and Insulin Resistance ', Molecular and Cellular Biology . https://doi.org/10.1128/MCB.00181-16

Skeletal muscle insulin resistance is a major characteristic of obesity and type 2 diabetes. Although obesity-mediated inflammation is causally associated with insulin resistance, the underlying mechanism is unclear. Here, we examined the effects of

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https://doi.org/10.1128/MCB.00181-16