Výsledky vyhledávání - "George H. Morrison"

Dynamic Secondary Ion Mass Spectrometry Analysis of Boron from Boron Neutron Capture Therapy Drugs in Co-Cultures: Single-Cell Imaging of Two Different Cell Types within the Same Ion Microscopy Field of Imaging

Autor: George H. Morrison, Subhash Chandra, Daniel R. Lorey

Publikováno v: Analytical Chemistry. 73:3947-3953

A co-culture, cryogenic SIMS methodology is presented for the quantitative analysis of cell type-dependent accumulation of boron delivered by BPA-F and BSH, two clinically approved drugs used in boron neutron capture therapy of cancer. T98G human gli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55710f84a8a77be348d2ab6509e5a4c6
https://doi.org/10.1021/ac0103266

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Boron microlocalization in oral mucosal tissue: implications for boron neutron capture therapy

Autor: G. M. Morris, H Patel, Peggy L. Micca, John W. Hopewell, George H. Morrison, M. Rezvani, Jeffrey A. Coderre, Duane R. Smith, Subhash Chandra

Publikováno v: British Journal of Cancer

Clinical studies of the treatment of glioma and cutaneous melanoma using boron neutron capture therapy (BNCT) are currently taking place in the USA, Europe and Japan. New BNCT clinical facilities are under construction in Finland, Sweden, England and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c33944a048aad0cfcf5535ea691b2cd
https://doi.org/10.1054/bjoc.2000.1148

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Imaging of Total Calcium in Urediospore Germlings of Uromyces by Ion Microscopy

Autor: Subhash Chandra, George H. Morrison, Gabriele M.E. Leinhos, Harvey C. Hoch

Publikováno v: Fungal Genetics and Biology. 27:77-87

Calcium has been implicated in growth and appressorium formation of urediospore germlings of the bean rust fungus, Uromyces appendiculatus. Using ion microscopy, a mass spectrometry-based imaging technique, intracellular stores of calcium were analyz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92aac620e6875f67495d845b4e794cd6
https://doi.org/10.1006/fgbi.1999.1135

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Evaluation of 26 Mg stable isotope as an in vivo tracer of magnesium transport for SIMS ion microscopy imaging studies

Autor: George H. Morrison, Subhash Chandra

Publikováno v: Journal of Microscopy. 188:182-190

Isotopic detection with high sensitivity, one of the most important features of ion microscopy, allows the in vivo application of stable isotopes as tracers for unravelling smaller tissue structures implicated with transport capabilities. The evaluat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7029bdd1119fe2fc81b6f52711bddd27
https://doi.org/10.1046/j.1365-2818.1997.2480806.x

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Evaluation of fracture planes and cell morphology in complementary fractures of cultured cells in the frozen‐hydrated state by field‐emission secondary electron microscopy: feasibility for ion localization and fluorescence imaging studies

Autor: Subhash Chandra, George H. Morrison

Publikováno v: Journal of Microscopy. 186:232-245

We have employed field-emission secondary electron microscopy (FESEM) for morphological evaluation of freeze-fractured frozen-hydrated renal epithelial LLC-PK1 cells prepared with our simple cryogenic sandwich-fracture method that does not require an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee6f580b3c38252f8af313d4220fecf
https://doi.org/10.1046/j.1365-2818.1997.2030763.x

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Image contrast of dielectric specimens in transmission mode near-field scanning optical microscopy: imaging properties and tip artefacts

Autor: Mark Holton, Gary A. Valaskovic, George H. Morrison

Publikováno v: Journal of Microscopy. 179:29-54

SUMMARY Near-field scanning optical microscopy (NSOM) is a scanned probe technique utilizing a subwavelength-sized light source for high-resolution imaging of surfaces. Although NSOM has the potential to exploit and extend the experimental utility of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::11d19016cc98373c80473ed850f69a0b
https://doi.org/10.1111/j.1365-2818.1995.tb03611.x

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Imaging ion and molecular transport at subcellular resolution by secondary ion mass spectrometry

Autor: George H. Morrison, Subhash Chandra

Publikováno v: International Journal of Mass Spectrometry and Ion Processes. 143:161-176

The transport of K + , Na + , and Ca 2+ were imaged in individual cells with a Cameca IMS-3f ion microscope. Strict cryogenic frozen freeze-dry sample preparations were employed. Ion redistribution artifacts in conventional chemical preparations are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ffe352f663ab5785555de1ab7300f9a
https://doi.org/10.1016/0168-1176(94)04134-s

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Golgi apparatus is involved in intracellular Ca2+ regulation in epithelial LLC-PK1 cells

Autor: George H. Morrison, A. J. Ridsdale, Xiaohui Zha, Subhash Chandra

Publikováno v: American Journal of Physiology-Cell Physiology. 268:C1133-C1140

Several lines of evidence suggest that the Golgi apparatus is involved in Ca2+ regulation in renal epithelial LLC-PK1 cells. Laser scanning confocal microscopy (LSCM) was employed to establish that a prominent perinuclear region is occupied mainly by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc268e265cd12c4bb2fc4a31cb08b27b
https://doi.org/10.1152/ajpcell.1995.268.5.c1133

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