Zobrazeno 1 - 4
of 4
pro vyhledávání: '"George H. Hutchins"'
Autor:
Sebastian Kiehstaller, George H. Hutchins, Alessia Amore, Alan Gerber, Mohamed Ibrahim, Sven Hennig, Saskia Neubacher, Tom N. Grossmann
Publikováno v:
Kiehstaller, S, Hutchins, G H, Amore, A, Gerber, A, Ibrahim, M, Hennig, S, Neubacher, S & Grossmann, T N 2023, ' Bicyclic Engineered Sortase A Performs Transpeptidation under Denaturing Conditions ', Bioconjugate chemistry, vol. 34, no. 6, pp. 1114-1121 . https://doi.org/10.1021/acs.bioconjchem.3c00151
Bioconjugate chemistry. American Chemical Society
Bioconjugate chemistry. American Chemical Society
Enzymes are of central importance to many biotechnological and biomedical applications. However, for many potential applications, the required conditions impede enzyme folding and therefore function. The enzyme Sortase A is a transpeptidase that is w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900073b38c8c7146288c8df4ea14297a
https://hdl.handle.net/1871.1/ce68c81f-f931-4ebd-93ed-e2d4861cf034
https://hdl.handle.net/1871.1/ce68c81f-f931-4ebd-93ed-e2d4861cf034
Autor:
Tinish Bhattacharya, George H. Hutchinson, Giacomo Pedretti, Xia Sheng, Jim Ignowski, Thomas Van Vaerenbergh, Ray Beausoleil, John Paul Strachan, Dmitri B. Strukov
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Specialized function gradient computing hardware could greatly improve the performance of state-of-the-art optimization algorithms. Prior work on such hardware, performed in the context of Ising Machines and related concepts, is limited to q
Externí odkaz:
https://doaj.org/article/d845a411e05c411ca813e6eff106341f
Autor:
Felix M. Paulussen, Gina K. Schouten, Carolin Moertl, Jolanda Verheul, Irma Hoekstra, Gregory M. Koningstein, George H. Hutchins, Aslihan Alkir, Rosa A. Luirink, Daan P. Geerke, Peter van Ulsen, Tanneke den Blaauwen, Joen Luirink, Tom N. Grossmann
Publikováno v:
Journal of the American Chemical Society. 144(33)
The use of antibiotics is threatened by the emergence and spread of multidrug-resistant strains of bacteria. Thus, there is a need to develop antibiotics that address new targets. In this respect, the bacterial divisome, a multi-protein complex centr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3c685c7ec6cad6f37fb845aeb2ae85
https://pubmed.ncbi.nlm.nih.gov/35945166
https://pubmed.ncbi.nlm.nih.gov/35945166
Autor:
J. L. Ross Anderson, Christopher Williams, Alice E. Parnell, Claire E.M. Noble, K.N. Sathish Yadav, Hector Blackburn, Ben Hardy, Charles Landau, Matthew P. Crump, Christiane Berger-Schaffitzel, A. Sofia F. Oliveira, Adrian J. Mulholland, George H. Hutchins, Paul R. Race
Publikováno v:
Hutchins, G H, Noble, C E M, Hardy, B, Parnell, A E, Yadav Kadapalakere, S, Williams, C, Race, P R, Oliveira, A S F, Crump, M P, Berger-Schaffitzel, C H, Mulholland, A J & Anderson, J L R 2020, ' Precision design of single and multi-heme de novo proteins ', bioRxiv . https://doi.org/10.1101/2020.09.24.311514
The de novo design of simplified porphyrin-binding helical bundles is a versatile approach for the construction of valuable biomolecular tools to both understand and enhance protein functions such as electron transfer, oxygen binding and catalysis. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5006239f8098146d6c3c2a46273ad39a
https://doi.org/10.1101/2020.09.24.311514
https://doi.org/10.1101/2020.09.24.311514