Zobrazeno 1 - 10
of 39
pro vyhledávání: '"George H. Goldsmith"'
Autor:
Terence J. Hadley, M. Marasa, George H. Goldsmith, Geetha Joseph, A. Huang, D. Vaughn, Benjamin Djulbegovic, J. Birkimer
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 2(3)
Summary. In a prospective study, we tested the hypothesis that an already reduced quality of life in haemophilia patients is further diminished in those haemophilia patients who contracted the human immunodeficiency virus (HIV) as a result of transfu
Autor:
Timothy Baize, George H. Goldsmith, Leslie Mudd, Roger H. Herzig, Donald R. Fleming, Craig Ziegler
Publikováno v:
American Journal of Clinical Oncology. 26:285-288
An open labeled randomized trial comparing the efficacy and cost of empirically applied cefepime (C) as monotherapy versus combination therapy consisting of ticarcillin and clavulanate potassium and aztreonam (T/A) was performed in febrile neutropeni
Autor:
George H. Goldsmith
Publikováno v:
International Journal of Hematology. 73:151-156
Alterations of hemostasis commonly accompany the progression of malignant disease and every known component of the hemostatic mechanism may be affected by this disease process. Nearly all patients with an active neoplasm will exhibit at least subtle
Publikováno v:
Journal of Hematotherapy & Stem Cell Research. 9:855-860
Chemotherapy, in addition to recombinant growth factors, has been effective in mobilizing stem cells. Unfortunately, the use of chemotherapy for this purpose has resulted in profound myelosuppression and increased morbidity. Docetaxel, the single mos
Autor:
Donald R. Fleming, Glenn D. Michelson, George H. Goldsmith, Renato V. LaRocca, Leela Bhupalam, Shawn D. Glisson
Publikováno v:
American Journal of Clinical Oncology: Cancer Clinical Trials. 23:349-352
A phase I study was designed to evaluate the toxicity of escalating doses of gemcitabine along with fixed-dose paclitaxel in patients heavily pretreated with chemotherapy or radiotherapy. All patients had no prior therapy with the study drugs and pos
Publikováno v:
British Journal of Haematology. 97:768-774
The antiphospholipid syndrome (APS) is associated with production of autoantibodies with lupus anticoagulant (LA) activity. These antibodies cause prolongation of in vitro clotting tests by inhibition of the conversion of prothrombin to thrombin in t
Autor:
D. Ware Branch, A. E. Gharavi, Silvia S. Pierangeli, E. Nigel Harris, George H. Goldsmith, Jacqueline Dean
Publikováno v:
Journal of Laboratory and Clinical Medicine. 128:194-201
Recently it has been suggested that antiphospholipid antibodies may not be specific for phospholipids but directed to beta2glycoprotein 1 (beta2GP1), phospholipid-beta2GP1 complexes, prothrombin, or prothrombin-phospholipid complexes. To explore this
Publikováno v:
British Journal of Haematology. 87:548-554
Lupus anticoagulants, commonly found in the immunoglobulin fraction of patients with the antiphospholipid syndrome (APS), and the normal plasma protein beta 2-glycoprotein 1 (beta 2GP1) may both contribute to the in vitro impairment of prothrombin ac
Autor:
D W Branch, George H. Goldsmith, Azzudin E. Gharavi, E. N. Harris, W. L. Dean, Silvia Pierangeli
Publikováno v:
British Journal of Haematology. 85:124-132
Recent studies have suggested that the lupus anticoagulant (LA) may be specific for prothrombin, prothrombin-phospholipid complexes, or beta 2 glycoprotein 1 (beta 2GP1) rather than phospholipids. We performed a series of experiments to determine whe
Publikováno v:
Clinical Immunology and Immunopathology. 54:247-255
Neutrophil (PMN) adherence is a critical component of host defense against infection. We questioned whether abnormalities of PMN adherence may be responsible, in part, for the increased susceptibility to infection in the elderly. We examined the adhe